Publications by authors named "Wen-Long Xing"
Article Synopsis
- The study aimed to assess the impact of Kuanxiong Aerosol (KXA) on coronary microcirculation in patients with unstable angina undergoing elective percutaneous coronary intervention (PCI).
- Patients were divided into a trial group receiving KXA and a control group, with evaluations of coronary microcirculation resistance (IMR) and cardiac markers both before and after the procedure.
- Results showed that the trial group had a significantly lower IMR after PCI, suggesting KXA may improve coronary microvascular dysfunction, although differences in myocardial injury rates were not statistically significant.
Objective: To investigate the involvement of endothelial cells (ECs)-derived exosomes in the anti-apoptotic effect of Danhong Injection (DHI) and the mechanism of DHI-induced exosomal protection against postinfarction myocardial apoptosis.
Methods: A mouse permanent myocardial infarction (MI) model was established, followed by a 14-day daily treatment with DHI, DHI plus GW4869 (an exosomal inhibitor), or saline. Phosphate-buffered saline (PBS)-induced ECs-derived exosomes were isolated, analyzed by miRNA microarray and validated by droplet digital polymerase chain reaction (ddPCR).
Background: Peri-procedural myocardial injury (PMI) is a common complication of percutaneous coronary intervention (PCI), which cannot be entirely avoided using available treatments. The findings of earlier research have shown that Shen-Yuan-Dan (SYD) capsules, a traditional Chinese medicine, can potentially alleviating PMI. This study aimed to confirm further this hypothesis in a rigorous, well-designed randomized controlled study.
View Article and Find Full Text PDFObjective: To evaluate the effect of Danhong Injection (, DH) on the index of microcirculatory resistance (IMR) and myocardial injury in patients with unstable angina undergoing elective percutaneous coronary intervention (PCI).
Methods: Seventy-eight patients with unstable angina were randomly divided into DH group (39 cases) and the control group (39 cases) during elective PCI. Randomization was performed using a random-number table.
Objective: To explore the effectiveness of Danhong Injection () on improving microcirculatory injury after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD).
Methods: A randomized controlled trial was conducted and 90 patients were enrolled. A random sequence was generated using statistical analysis software.
Article Synopsis
- The study aimed to analyze trends in patient characteristics, treatments, and outcomes for acute myocardial infarction (AMI) in tertiary Chinese medicine hospitals in China from 2006 to 2013.
- Data was collected from two nationwide surveys involving 2,311 AMI patients, revealing an increase in younger patients and higher prevalence of risk factors like hypertension and diabetes over the years.
- Although hospital mortality rates slightly decreased, the use of advanced treatments like reperfusion and revascularization significantly increased, indicating improved treatment capabilities in these hospitals.
Background: Peri-procedural myocardial injury (PMI) during percutaneous coronary intervention (PCI) will result in an unfavorable clinical prognosis in patients, thus urgently necessitating effective drug treatment measures. Shen-Yuan-Dan (SYD) capsules are a traditional Chinese medicine (TCM) preparation that have been found to have potential myocardial protection effects during the peri-procedural phase of PCI in previous clinical and basic research; however, there is a lack of rigorous, randomized, and controlled studies. The aim of this study is to evaluate the efficacy and safety of SYD in decreasing PMI.
View Article and Find Full Text PDFAdditives can have a significant impact on the pyrolysis process. The effects of three additives (CaO, MSW char and biomass) on the pyrolysis characteristics of municipal solid waste (MSW) were investigated using a fixed-bed reactor. In addition, the effects of additives and temperature on the MSW pyrolysis product yield, the composition of MSW pyrolysis gases, and the composition of MSW pyrolysis tar were investigated using fixed bed reactor, GC-MS and FTIR, respectively.
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