Circular RNA Pum_0014 Targets miR-146a-5p/NF2 Axis to Regulate VEGF/PAK1 Pathway and Reduce H2O2-induced Cardiomyocyte Apoptosis.

Circular RNAs (circRNAs) have emerged as essential regulators in cardiovascular disease, including acute myocardial infarction (AMI). This study investigated the role of circRNA Pum1_0014 in myocardial infarction (MI) and its underlying mechanisms using an H9C2 cell model. Through Sanger sequencing, nucleic acid electrophoresis, RNase R, and transcriptional inhibition experiments, Pum1_0014 was identified as a novel circRNA.

Complete mitochondrial genome of melon fly, (Diptera:Tephritidae) from Kunming, Southwest China and the phylogeny within subfamily Dacinae.

The melon fly, (Diptera:Tephritidae) is an important invasive pest and distributed throughout tropical, subtropical countries and areas. In this study, we report the complete mitochondrial genome of the fly with 15, 685 base pair in length, which includes 37 genes (the large and small ribosomal RNA subunits, 22 transfer RNA genes, 13 genes encoding mitochondrial proteins) and a non-coding A + T-rich control region. Molecular phylogeny indicated that there was a high bootstrap value supported among and belonging to the complex.

Complete mitochondrial genome of the black-winged fly, (Diptera: Tephritidae) and its phylogenetic relationship within family Tephritidae.

The black-winged fly, (Diptera: Tephritidae), is an insect pest of bamboo shoot, mainly distributed in Thailand, Malaysia and Yunnan Province and Guangxi Autonomous Region, China. The complete sequence of the mitogenome of has been determined in this study. The whole mitogenome sequence is 16,536 bp in length, which totally contains 13 protein-coding genes (PCGs), 2 rRNA genes, 22 tRNA genes, and a non-coding region (putative control region, CR).

Complete mitochondrial genome of the bamboo-shoot fruit fly, (Diptera: Tephritidae) and its phylogenetic relationship within family Tephritidae.

(Diptera: Tephritidae) is an insect pest of bamboo shoot and distributed in the Yunnan and Sichuan Provinces, Southwest China. Complete mitogenome sequence has been determined in this study. The circular genome is 15384 bp long and contains a standard gene complement, that is, the large and small ribosomal RNA subunits, 22 transfer RNA genes, 13 genes encoding mitochondrial proteins, and a non-coding A + T-rich control region.

Complete mitogenome for the ber fruit fly, (Diptera: Tephritidae) from Toksun, Northwest China and its phylogenetic relationship within family Tephritidae.

(Diptera: Tephritidae), commonly known as the ber fruit fly, is the most destructive insect pest of 'ber' (jujube) throughout Asia and Western Europe. Complete sequence of the mitogenome of has been determined in this study. The circular genome is 15,267 bp long and contains a standard gene complement, that is, the large and small ribosomal RNA subunits, 22 transfer RNA genes, 13 genes encoding mitochondrial proteins, and a non-coding A + T-rich control region.

[Expression of Peroxiredoxin-6 Gene in Patients with Acute Myeloid Leukemia and Its Clinical Significance].

Objective: To study the expression of Peroxiredoxin-6 (Prdx6) gene in elderly patients with acute myeloid leukemia (AML) and its clinical significance.

Methods: The expression level of Prdx6 in bone marrow cells of 33 cases of AML, 8 cases of CML and 11 cases of other blood diseases was detected by PCR. The correlation of the abnormal expression of Prdx6 with patient age and blood routine parameters was further analyzed.

Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.

Aim: To clarify the underlying mechanism of formin-like 3 (FMNL3) in the promotion of colorectal carcinoma (CRC) cell invasion.

Methods: The biological function analyses of FMNL3 were performed by gain- and loss-of function approaches. Changes in the F-actin cytoskeleton were detected by the technologies of phalloidin-TRITC labeling and confocal microscopy.

Characterization of mitochondrial genome and phylogenetic implications for Chinese black ant, (Hymenoptera: Formicidae).

Chinese black ant, Smith, also known as Roger has been used as a traditional edible insect and Chinese medicine in China and some southeast countries for thousands of years. In this study, Mitogenome of this species was assembled with high coverage using Illumina sequencing data and is 15,806 bp long in size. The base composition is 37.