[Experimental teaching reform of polymer molar mass determination using gel permeation chromatography coupled with light scattering].

Gel permeation chromatography coupled with light scattering (GPC-LS) is among the most common methods for determining the molar masses of polymers. GPC-LS is widely used in polymer science research and has been adopted for many industrial applications owing to its high sensitivity, accuracy, and precision. The determination of polymer molar masses using GPC-LS is an important experimental component of the "Polymer Physics Experiments" course.

[Moisture content measurement model of whole package of Chinese medicinal materials based on microwave transmission technology].

In view of the relatively low representativeness of manual sampling inspection, and long time-consuming in oven detection of moisture content, which delayed the subsequent production period, this paper proposed a scheme for rapid moisture quantitative detection for Chinese medicinal materials by microwave transmission technology, and took 8 different types of Chinese medicinal mate-rials as examples to analyze the feasibility and reliability of the scheme for the detection results of moisture content of the whole package of Chinese medicine. In the experiment, the least square method was used to establish the measurement model of microwave absorption rate-moisture content for each kind of medicinal material. The results showed that the microwave transmission measurement of moisture content achieved high-precision measurement of the moisture content of Schisandrae Chinensis Fructus, Ziziphi Spinosae Semen, Poria, Pheretima, Lilii Bulbus, Scutellariae Radix, and Galli Gigerii Endothelium Corneum.

N--Feruloyloctopamine Wakes Up BBC3, DDIT3, CDKN1A, and NOXA Signals to Accelerate HCC Cell Apoptosis.

N--Feruloyloctopamine (FO), a natural compound, was reported in our previous study to inhibit a tumor cell malignant phenotype by AKT- and EMT-related signals and might be used as a promising drug for HCC treatment. However, the specific targets and detailed mechanisms still need to be clarified. Screening with RNA-Seq in Huh7 cells treated with FO revealed that 317 genes were modulated, of which 188 genes were upregulated and 129 genes were downregulated.

Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts.

This study investigated the effects of X-ray irradiation on primary rat cardiac fibroblasts (CFs) and its potential mechanism, as well as whether sodium tanshinone IIA sulfonate (STS) has protective effect on CFs and its possible mechanism. Our data demonstrated that X-rays inhibited cell growth and increased oxidative stress in CFs, and STS mitigated X-ray-induced injury. Enzyme-linked immuno-sorbent assay showed that X-rays increased the levels of secreted angiotensin II (Ang II) and brain natriuretic peptide (BNP).

Design and performance of tapered cubic anvil used for achieving higher pressure and larger sample cell.

In order to increase the maximum cell pressure of the cubic high pressure apparatus, we have developed a new structure of tungsten carbide cubic anvil (tapered cubic anvil), based on the principle of massive support and lateral support. Our results indicated that the tapered cubic anvil has some advantages. First, tapered cubic anvil can push the transfer rate of pressure well into the range above 36.

[Role of the marginal division of human neostriatum in working memory capacity for numbers received through hearing: a functional magnetic resonance imaging study].

Objective: With the help with functional magnetic resonance imaging (fMRI) technique, we aim to clarify whether the marginal division of the striatum (MrD) is involved in the working memory function of human brain for remembering numbers received through hearing.

Methods: Thirteen healthy volunteers were instructed to undertake both a working memory task, in which the subjects were asked to remember as many numbers read to them as possible, and a non-working memory control task, in which the subjects were not asked to remember the numbers. FMRI of the brain was performed in the 2 groups while the tests were being carried out separately, and the activity of the brain regions was compared between these 2 tasks.

[Expression of immediate-early genes c-fos and c-jun in the marginal division of striatum during learning and memory].

Objective: To study the expression of immediate-early genes c-fos and c-jun in the marginal division (MrD) of rat striatum during learning and memory.

Methods: After Y-maze training in rats, the expression of immediate-early genes c-fos and c-jun in the MrD was investigated immunocytochemically.

Results: After 1 h of Y- maze training, the expression of c-Fos and c-Jun proteins was significantly enhanced in the MrD, where c-Jun protein in particular was more intensely expressed than in other parts of the striatum.

[Effects of hypoxia on AChE and NADPH-d levels in the marginal division and learning and memory functions of rats].

Objective: To observe the pathological changes and changes in acetylcholinesterase (AChE) and reduced nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) levels in the marginal division (MrD) following hypoxia, and explore the relation of hypoxia to damages of learning and memory functions.

Methods: Hypoxia models were established in 40 SD rats by treatment with the mixture of 8% oxygen and 92% nitrogen 5 times daily for 5 consecutive days, and the sham-hypoxia group was constituted by 10 rats receiving normal oxygen supply in the same manner as above. Another 10 untreated rats were used as normal control.