Treatment of refractory giant macular hole by vitrectomy with internal limiting membrane transplantation and autologous blood.

Aim: To investigate the effect of internal limiting membrane transplantation and autologous blood on treating refractory giant macular hole.

Methods: Thirty-seven eyes with giant macular hole of the smallest hole diameter >700 µm, the maximum diameter of the substrate >1000 µm and hole formation factor <0.6 underwent surgical treatment.