[Effects of heroin and purine nucleotide compensation on neutral alpha-glucosidase in rat epididymides].

Objective: To study the changes of neutral alpha-glucoside activity in the epididymis of heroin-dependent and heroin-withdrawal rats, and to investigate the effects of intervention with purine nucleotide (AMP and GMP).

Methods: Eighty Wistar rats were randomly divided into 8 groups of equal number, control, nucleotide, heroin, heroin + nucleotide, 3 d withdrawal, 9 d withdrawal, 3 d nucleotide (nucleotide administrated for 3 days after heroin withdrawal) and 9 d nucleotide (nucleotide administrated for 9 days after heroin withdrawal). Neutral alpha-glucosidase activity in the epididymis was detected in each group of rats.

[Autosomal DAZL single nucleotide polymorphisms not associated with male infertility in northeast China].

Objective: To investigate the association of male infertility with single nucleotide polymorphisms of the autosomal DAZL gene.

Methods: Semen samples were collected from infertile men (infertility group, n=144) and healthy fathers (fertility group, n=53) in the northeast of China, and the former was further divided into 5 subgroups according to the WHO diagnostic criteria for oligoasthenoteratozoospermia (1999) i.e.

[The effect of semen antisperm antibody on human sperm acrosin activity].

Objectives: To study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.

Methods: AsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.

Results: AsAb positive rate was 10.