Publications by authors named "Wen-Jin Fan"
Front Cell Dev Biol
July 2022
Article Synopsis
- - Osteoarthritis (OA) is a widespread health issue with unclear causes, and there are currently no effective drugs that modify the disease; exosomes play a crucial role in its pathophysiology by influencing inflammation and cartilage degradation.
- - Exosomes are small vesicles that carry proteins, RNAs, and other molecules, which can be found in synovial fluid and plasma, and their levels change as OA progresses, indicating potential as diagnostic biomarkers.
- - Exosomes from mesenchymal stem cells show promise for therapeutic use in OA by promoting cartilage restoration and balancing inflammatory processes, especially when combined with materials like hydrogels for tissue engineering.
