Publications by authors named "Wen-Jiang Qian"

Bone marrow mesenchymal stem cells (BMSC) are promising candidates for the treatment of trans-territory perforator flap necrosis. However, the low retention and survival rate of engrafted BMSCs limit their therapeutic efficacy. Strategies either modifying BMSCs or alleviating the inflammatory environment may solve this problem.

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Article Synopsis
  • The study investigates using adipose-derived stem cells (ADSCs) alongside chondrocytes to improve cartilage tissue engineering for craniofacial defects.
  • It evaluates how these cells grow and differentiate when co-cultured with transforming growth factor-beta (TGF-β3) compared to being cultured alone.
  • Results show that co-culturing ADSCs with chondrocytes promotes better cell growth and cartilage formation, indicating potential for improved cartilage repair strategies.
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Objective: To find a satisfied and applicable repairing method for big auricle defect.

Methods: an auricular posterior flap with has two subcutaneous pedicles on mastoidea, was applied for repairing of big auricle defect. A framework of rib cartilage was embedding into the flap to shape auricle.

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