Publications by authors named "Wen-Hui Liang"

Background: Wireless capsule endoscopy (WCE) has become an important noninvasive and portable tool for diagnosing digestive tract diseases and has been propelled by advancements in medical imaging technology. However, the complexity of the digestive tract structure, and the diversity of lesion types, results in different sites and types of lesions distinctly appearing in the images, posing a challenge for the accurate identification of digestive tract diseases.

Aim: To propose a deep learning-based lesion detection model to automatically identify and accurately label digestive tract lesions, thereby improving the diagnostic efficiency of doctors, and creating significant clinical application value.

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Article Synopsis
  • Breast cancer is a prevalent disease that causes over 3.7 million deaths annually; the study focuses on two molecules, DSCAM-AS1 and miR-204-5p, which play opposing roles in cancer progression.
  • DSCAM-AS1 is found to be overexpressed in breast cancer, promoting cell proliferation and invasion by downregulating miR-204-5p, which has anti-tumor effects, while RRM2 is also identified as being upregulated and contributing to aggressive cancer behavior.
  • The research suggests that targeting the interaction between DSCAM-AS1, miR-204-5p, and RRM2 could offer new therapeutic strategies for treating breast cancer.
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The asymmetric unit of the title compound, C(5)H(7)N(5) (2+)·2C(7)H(7)O(3)S(-)·H(2)O, consists of one diprotonated adeninium cation, two p-toluene-sulfonic acid anions and one water mol-ecule. In the crystal, the cations and anions are connected through N-H⋯O hydrogen bonds forming R(2) (2)(8) and R(2) (2)(9) graph-set motifs. The solvent water mol-ecule links cations and anions through O-H⋯O and N-H⋯O hydrogen bonds, generating a two-dimensional layer parallel to (10).

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In the title compound, C(17)H(18)ClN(3)O(3), the dihedral angle between the planes of the two benzene rings is 1.03 (7)°. The overall conformation of the mol-ecule is influenced, in part, by electron delocalization and by an intra-molecular bifurcated O-H⋯(O,N) hydrogen bonds.

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In the title compound, C(16)H(9)BrO(5)·2C(3)H(7)NO, the chromene ring system is essentially planar. The two dimethyl-formamide solvent mol-ecules are linked by inter-molecular O-H⋯O hydrogen bonds to the 6-bromo-3-hydr-oxy-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid molecules.

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In the title compound, C(11)H(13)N(2)O(+)·C(2)H(3)O(2) (-)·H(2)O, the dihedral angle between the benzene ring and the imidazole ring is 7.83 (6)°. In the crystal structure, N-H⋯O and O-H⋯O hydrogen bonds form a two-dimensional network.

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3,5-Dibromo-2-hydroxy-benzoic acid.

Acta Crystallogr Sect E Struct Rep Online

December 2007

The title compound, C(7)H(4)Br(2)O(3), has an intra-molecular O-H⋯O=C hydrogen bond and aggregates to form hydrogen-bonded dimers via O-H⋯O inter-actions. The formation of zigzag one-dimensional mol-ecular tapes via C-H⋯Br inter-actions and π-π stacking inter-actions (inter-planar separation = 3.42 Å) completes the crystal structure.

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The europium(III) ion in the title compound, [Eu(2)(C(8)H(6)NO(2))(6)(C(12)H(8)N(2))(2)]·5H(2)O, is coordinated by seven carboxyl-ate O atoms and two N atoms from one phenanthroline mol-ecule. The carboxyl-ate groups of 3-(3-pyrid-yl)acrylate link pairs of europium(III) ions, forming centrosymmetric dinuclear units, which further assemble into a sheet parallel to the (001) plane through hydrogen-bonding inter-actions involving the uncoordinated water mol-ecules. One water molecule is disordered.

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