Publications by authors named "Wen-Hua Jia"
[Establishment of Mouse Model with Humanized Chronic Myeloid Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2016
Article Synopsis
- The study aimed to create a BALB/c nude mouse model to investigate human chronic myeloid leukemia (CML) for research purposes.
- Mice underwent specific treatments before being injected with bone marrow cells from CML patients, and various health indicators (like weight, appetite, and blood cell counts) were monitored over time.
- Results showed that mice receiving CML cells displayed significant health decline, with notable increases in leukemia cell counts and the presence of the BCR/ABL fusion gene, confirming the model's effectiveness for studying human CML.