Publications by authors named "Wen-Hao Ma"

Simultaneous detection of multiple tumor markers is of great significance for an accurate diagnosis and early treatment of cancer. Electrochemical homogeneous biosensing strategies have been shown to have advantages, such as high sensitivity and no electrode modification, but they are still a challenge in the field of simultaneous detection of multiple tumor markers. The ER, PR, HER2, and Ki67 proteins are the standard biomarkers for the clinical molecular typing of breast cancer.

View Article and Find Full Text PDF
Article Synopsis
  • - This study looked at how cannabis and alcohol use affects sleep quality in individuals with anxiety, analyzing data from 347 participants over 30 days.
  • - Findings showed that participants generally experienced better sleep after using cannabis alone or in combination with alcohol, while alcohol alone did not improve sleep.
  • - The research suggests that those who use alcohol and cannabis more frequently tend to sleep better after using cannabis-only, indicating that usage patterns might influence sleep outcomes.
View Article and Find Full Text PDF

Aim: To evaluate the potential of two trabecular meshwork (TM)-specific promoters, Chitinase 3-like 1 (Ch3L1) and matrix gla protein (MGP), for improving specificity and safety in glaucoma gene therapy based on self-complementary AAV2 (scAAV2) vector technologies.

Methods: An scAAV2 vector with C3 transferase (C3) as the reporter gene (scAAV2-C3) was selected. The scAAV2-C3 vectors were driven by Ch3L1 (scAAV2-Ch3L1-C3), MGP (scAAV2-MGP-C3), enhanced MGP (scAAV2-eMGP-C3) and cytomegalovirus (scAAV2-CMV-C3), respectively.

View Article and Find Full Text PDF

Introduction: The loss of retinal pigment epithelial (RPE) cells is associated with the etiology of diabetic retinopathy (DR). This study investigated the effects of circular RNA ZNF532 (circZNF532) on apoptosis and pyroptosis of RPE cells.

Materials And Methods: Blood samples were collected from patients with DR and healthy volunteers.

View Article and Find Full Text PDF

Objective: To summarize the endoscopic screening findings in high-risk population of esophageal and gastric carcinoma and analyze influential factors related to screening.

Methods: In seven selected cities and counties with high incidences of esophageal carcinoma, people at age of 40-69 were set as the target population. Those with gastroscopy contradictions were excluded, and all who were voluntary and willing to comply with the medical requirements were subjected to endoscopic screening and histological examination for esophageal, gastric cardia and gastric carcinoma in accordance with national technical manual for early detection and treatment of cancer.

View Article and Find Full Text PDF