Synopsis of recent research by authors named "Wen-Hai Shao"
- Wen-Hai Shao's research primarily focuses on the pathogenesis of systemic lupus erythematosus (SLE) and its complications, particularly lupus nephritis (LN), emphasizing the role of transcription factors and epigenetic alterations in disease progression and potential therapeutic interventions
- His findings highlight the involvement of Axl receptor tyrosine kinase and its regulatory networks in renal cell proliferation and survival, which contributes to the development of lupus nephritis, with implications for targeted therapies in glomerulonephritis
- Shao's work also extends to understanding the broader mechanisms of immune dysregulation in SLE, examining the epigenetic modifications in immune cells and their contribution to autoimmune pathologies, thus offering insights into potential genetic and epigenetic targets for therapeutic development
