World J Gastroenterol
July 2005
Aim: To investigate the damaging effect of high-intensity focused ultrasound (HIFU) on cancer cells and the inhibitory effect on tumor growth.
Methods: Murine H22 hepatic cancer cells were treated with HIFU at the same intensity for different lengths of time and at different intensities for the same length of time in vitro, the dead cancer cells were determined by trypan blue staining. Two groups of cancer cells treated with HIFU at the lowest and highest intensity were inoculated into mice.
Sichuan Da Xue Xue Bao Yi Xue Ban
January 2004
Objective: To investigate the killing effect of high intensity focused ultrasound (HIFU) on human tumor cells and study the mechanism of its action.
Methods: Human breast cancer cells MCF-7 were treated with different intensity of HIFU in vitro and incubated. The killing effect and proliferation inhibition effect of HIFU on tumor cells were investigated with the methods of trypan blue exclusion assay, MTT assay and colony formation assay.