Anti-inflammatory activity of chitosan nanoparticles carrying NF-κB/p65 antisense oligonucleotide in RAW264.7 macropghage stimulated by lipopolysaccharide.

The purpose of this present study is to prepare NF-κB/p65 antisense oligonucleotide loaded chitosan nanoparticles (NPs) and evaluate their physicochemical characterization and antisense effects in RAW264.7 macrophages. Condensed nanoparticles with mean particle size of 128±16nm, average Zeta potential of 19.

Synthesis, characterization and DFT studies of two new pi-conjugated-conjugated pyridine-based tetrathiafulvalene derivatives.

Two new pi-conjugated pyridine-based tetrathiafulvalene derivatives, 2-(2- (4,5-bis(methylthio)-1,3-dithiol-2-ylidene)-6-phenyl-[1,3]dithiolo[4,5-b][1,4]dithiin-5-yl)pyridine (2a) and 3-(2-(4,5-bis(methylthio)-1,3-dithiol-2-ylidene)-6-(pyridin-2-yl) -[1,3]dithiolo[4,5-b][1,4]dithiin-5-yl)quinoline (2b), have been synthesized and characterized by 1H NMR, elemental analysis and mass spectroscopies. The compound 2a has also been studied by X-ray crystallography and theoretical calculations using density functional theory (DFT) framework with B3LYP/6-311+G(d,p) level of theory. Its crystal structure is triclinic system, space group P1-.

Fluorescence enhancement and lifetime modification of single nanodiamonds near a nanocrystalline silver surface.

Fluorescent nanodiamond (FND) contains nitrogen-vacancy defect centers as fluorophores. The intensity of its fluorescence can be significantly enhanced after deposition of the particle (35 or 140 nm in size) on a nanocrystalline Ag film without a buffer layer. The excellent photostability (i.

The use of plasma progesterone profiles to predict the reproductive status of anestrous gilts and sows.

A plasma progesterone profile obtained from three consecutive blood samples with an interval of 7 days was evaluated for usefulness as the basis for the diagnosis and treatment of anestrous gilts and sows. Four reproductive statuses were categorized based on the plasma progesterone levels and pathological examination of the reproductive organs from 25 gilts and 12 sows with anestrus. Category 1: fluctuating (at least one sample <2.