Extracorporeal Shock Wave Therapy for Limb Dysfunction after Stroke: A Systematic Review and Meta-analysis.

Objective: Recently, extracorporeal shock wave therapy (ESWT) has emerged as a novel and noninvasive approach for alleviating spasticity and pain, improving motor dysfunction after stroke. To determine the effectiveness of ESWT and the effects of shock wave parameters in relieving spasticity, pain, and motor dysfunction following stroke.

Design: We conducted a systematic search of PubMed, EBSCOhost, Embase, Cochrane Library, and Web of Science databases for randomized controlled trials on ESWT for limb dysfunction after stroke from inception until February 1, 2023.

Resistance to Naïve and Formative Pluripotency Conversion in RSeT Human Embryonic Stem Cells.

One of the most important properties of human embryonic stem cells (hESCs) is related to their primed and naïve pluripotent states. Our previous meta-analysis indicates the existence of heterogeneous pluripotent states derived from diverse naïve protocols. In this study, we have characterized a commercial medium (RSeT)-based pluripotent state under various growth conditions.

GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation.

Growth differentiation factor 15 (GDF15) belongs to the Transforming growth factor β(TGF-β) superfamily. The decrease of GDF15 in the serum of pregnant women was associated with miscarriage. Both IHC and ELISA assays showed that GDF15 in trophoblast tissue and serum of pregnant women who miscarried was significantly lower than in those who had a live birth.

Two layered galloborates from centric to acentric structures: syntheses and NLO properties.

Two layered galloborates (GBOs), NaGaBO (1) and NaGa[BO(OH)]·2B(OH) (2), have been solvothermally made. 1 exhibits an unprecedented layer built by GaO tetrahedra and BO clusters. 2 was made by raising the ratio of B/Ga and the reaction temperature of 1, featuring a 2D acentric layer built by GaO groups and BO(OH) clusters.

Two new Cu-based borate catalysts with cubic supramolecular cages for efficient catalytic hydrogen evolution.

Focusing on renewable energy, we are devoted to developping efficient, robust and low cost water reduction catalysts (WRCs). Two new Cu-based borate catalysts, namely HNaK[(μ-O)Cu@BO(OH)]·21HO (1) and HRbK[(μ-O)Cu@BO (OH)]·15HO (2), with cubic supramolecular cages were synthesized under a hydrothermal condition. Moreover, new copper complexes were applied as water reduction catalysts (WRCs) in the presence of [Ir(ppy)(dtbbpy)][PF] as photosensitizer and triethanolamine (TEOA) as the sacrificial electron donor.

Serum interleukin-33 as a novel marker for long-term prognosis and recurrence in acute ischemic stroke patients.

Objectives: Interleukin-33, a newly identified member of interleukin-1 family, had been confirmed to play a crucial role in regulating inflammatory responses in various disease. However, the exact role of interleukin-33 in the disease process of acute ischemic stroke still remains unclear. This study aims to demonstrate the relationship between interleukin-33 levels and long-term functional outcome as well as ischemic stroke recurrence.

The association of matrix metalloproteinase-1 genetic polymorphism (-1607 1G>2G) with colorectal cancer: a meta-analysis.

Several case-control studies on the relation between matrix metalloproteinase (MMP)-1 gene -1607 1G>2G polymorphism and colorectal cancer do not have similar conclusions. The previous two meta-analyses focusing on the same issue also were inconsistent. To further evaluate the relation between the MMP-l gene polymorphism and colorectal cancer, we selected eight case-control studies related to MMP-1 gene polymorphism and colorectal cancer by searching MEDLINE, Embase, CANCERLIT, American Association for Cancer Research, Chinese Biomedical Literature Database, Chinese CNKI, and Wanfang database.

[Pharmacokinetics and bioequivalence of domestic trimetazidine formulations].

Objective: To compare the pharmacokinetics and bioequivalence between domestic hydrochloric trimetazidine capsules and imported hydrochloric trimetazidine tablets in healthy male Chinese volunteers after single oral administration.

Methods: A single oral dose (test and reference formulations) was given to 24 healthy male Chinese subjects according to an open randomized crossover design. The blood samples were collected before and after administration.

CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer.

CD146 has been regarded as a novel potential therapeutic target for multiple cancers. The aim of the study was to investigate the expression of CD146 in gastric cancer and evaluate its clinical-pathological and prognostic significance. The expression of CD146 and three epithelial-mesenchymal transition (EMT)-related proteins (E-cadherin, β-catenin and vimentin) was examined in 144 gastric cancers by immunohistochemistry.

Isolated pancreatic granulocytic sarcoma: a case report and review of the literature.

Granulocytic sarcoma (GS) is an extramedullary tumor mass consisting of immature myeloid cells. Isolated pancreatic granulocyte sarcoma is extremely rare. We report a very unusual pancreatic granulocytic sarcoma in a patient without acute myeloid leukemia.

Pharmacokinetic interaction between cefaclor and bromhexine in healthy Chinese volunteers.

Objective: To determine the pharmacokinetic interaction between cefaclor and bromhexine in healthy Chinese volunteers.

Methods: Twelve subjects received a cefaclor (CEF) treatment, a bromhexine (BHX) treatment, and a co-treatment of CEF and BHX with a 3 x 3 Latin square design. The wash-out time between periods was 14 days.

[The fabrication and chroma study of a kind of custom shade guide with metal substrate].

Purpose: This study was to explore the chroma of a custom shade guide with metal substrate.

Methods: A custom shade guide sample was fabricated using the central maxillary incisor as a model,which was corresponding to the colour of VITAPAN shade guide.The colour of each shade tab was measured with PR-650 spectrophotometer when every porcelain was added.

[Comparison of color character of VITA shade guide and the custom shade guide].

Objective: To compare the color character of VITA shade guide and the custom shade guide with metal substrate.

Methods: Color of 9 sites of 5 series of VITA shade guides and custom shade guides with metal substrate were measured by means of PR-650 spectrophotometer.

Results: The color range of VITA shade guide were that L* was 56.

[Lymph node micrometastases and expression of metastasis-related gene proteins in patients with colorectal cancer].

Objective: To study lymph node micrometastases (LNMM), expression of nm23-H(1), MMP(9), TIMP(2) proteins, and their relationship and clinical significance in patients with stage Dukes B colorectal cancer.

Methods: Thirty patients with stage Dukes B colorectal cancer were studied. LNMM in these patients was detected by immunohistochemical anti-cytokeratin 20 (CK20) staining.