Swieteliacates S-U, phragmalin limonoids, from the leaves of .

Three novel phragmalin-type limonoids, swieteliacates S-U (1-3), were isolated from leaves, alongside four previously identified limonoids (4-7). The structures, encompassing absolute configurations, were delineated through 1D and 2D NMR analyses, high-resolution mass spectrometry (HR-MS), and NMR and ECD calculations. Swieteliacate S (1) is a distinctive cryptate comprising a tricyclo[4.

Limonoids from Swietenia macrophylla and their antitumor activities in A375 human malignant melanoma cells.

Swietelinins A - C (1-3) and swieteliacates F - R (4-16), sixteen new limonoids and 18 known limonoids (17-34) were isolated from Swietenia macrophylla. The absolute configurations of these compounds were defined by using a combination of electronic circular dichroism data analysis and single-crystal X-ray diffraction data. Swieteliacate J (10) is the first limonoid possessing an unusual 8β, 9β-epoxy ring system.

Kalshiolin A, new lignan from .

The Asian plant has been used as food and ethnologic medicine for over a thousand years. In this study, we isolated and identified one new lignan, kalshiolin A (), and 12 known lignans (). The structures were characterized by the comprehensive analyses of spectroscopic data (HR-ESI-MS, IR, 1D, and 2D-NMR) and the absolute configuration of was determined from ECD calculations.

Arahyside A, a new norsesquiterpene from .

Six compounds were isolated from the stems and leaves of , including a new norsesquiterpene, arahyside A (), and five known compounds, 4-(2-methoxyethyl)benzene-1,2-diol (), (1(,),2(,))-1-phenylpropane-1,2-diol (), tachioside (), 1,3-benzenediol (), demethylmedicarpin (). Extensive spectroscopic methods, containing HR-EI-MS, NMR and ECD were used for structural elucidation of this new compound . Furthermore, its cytotoxicity was evaluated by MTT assay.

Chemical Structures and Biological Activities of Limonoids from the Genus (Meliaceae).

is a genus in the plant family Meliaceae. This genus contains seven to eight known species, found in the tropical and subtropical regions of the Americas and West Africa. Thus far, more than 160 limonoids have been isolated from four species of the genus .