Publications by authors named "Wen-Bin Duan"

Article Synopsis
  • This study investigated how Dalbergia cochinchinensis could improve coronary microvascular dysfunction induced by microsphere embolization in rats using advanced visualization and metabolomics techniques.
  • A total of sixty male SD rats were divided into five groups, including control and varying doses of the D. cochinchinensis extract administered over seven days.
  • Results indicated that D. cochinchinensis significantly improved blood flow, reduced fibrinogen levels, and decreased myocardial enzyme levels compared to the control group, suggesting potential therapeutic effects.
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Background: Lenvatinib or Sorafenib combined with programmed cell death protein-1 (PD-1) inhibitor as recommend treatment of advanced hepatocellular carcinoma (HCC) with extrahepatic metastasis (EHM). We aimed to compared the prognosis of Lenvatinib plus PD-1 inhibitor (Len+PD-1) versus Sorafenib plus PD-1 (Sora+PD-1) as an initial therapy for HCC with EHM.

Methods: Incorporating a sum of 229 HCC patients with EHM were encompassed within this study, with 127 in the Sora+PD-1 group and 102 in the Len+PD-1 group.

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Background: The evidence of radiofrequency ablation (RFA) following transarterial chemoembolisation (TACE) combined with sorafenib for intermediate-stage recurrent hepatocellular carcinoma (RHCC) is limited. Patient responses to this treatment vary because of the heterogeneous nature of RHCC, making it important to identify patients who are most likely to benefit from this combination therapy. The aim of this study was to evaluate the efficacy of RFA following TACE and sorafenib for the intermediate-stage RHCC.

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Two new benzophenone derivatives ( and ), named Pogonatone and pogonatone , were isolated from the moss . Their structures were elucidated by spectroscopic data analyses. The cytotoxicity of compounds for HepG2, HCT-116, A-549 and PANC-1 cells line was also evaluated by using the MTT method.

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Article Synopsis
  • The study aimed to compare high-flow nasal cannula oxygen therapy (HFNC) with conventional nasal cannula oxygen therapy (CNC) in high-risk patients with obstructive sleep apnea during prostate biopsies under anesthesia.
  • Results showed that patients receiving HFNC had significantly better oxygen levels and fewer instances of hypoxia and other airway complications compared to those on CNC.
  • Overall, HFNC was found to be a more effective option for improving oxygenation and managing airways in these patients without affecting surgery time or anesthesia dosage.
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This study aims to compare the effects of feeding haw pectin (HP), haw pectin hydrolyzates (HPH), and haw pectin pentasaccharide (HPPS) on the cholesterol metabolism of hypercholesterolemic hamsters induced by high-cholesterol diets. The animals were fed a standard diet (SD), high-cholesterol diet (HCD), or HCD plus HP, HPH, or HPPS at a dose of 300mg/kg body weight for 4weeks. Results showed that HPPS was more effective than HP and HPH in decreasing the body weight gain (by 38.

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