Alkaloids constituents from the roots of (Cav.) Trin. ex Steud. with their cytotoxic activities.

Two new alkaloids, phranisines AB (), along with two known compounds, N-p-Coumaroyl serotonin () and N-p-coumaroyl-tryptamine (), were isolated from the roots of . The structures of were established on the basis of extensive spectroscopic. The absolute configuration of compounds were identified through quantum-chemical electronic circular dichroism (ECD) calculation compared with their experimental CD.

and induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway.

Oxysophoridine (OSR) is a major active alkaloid extracted from L. The aim of the present study was to investigate the induction of the apoptotic effects of OSR on colorectal cancer cells and . The results of the MTT and colony formation assays demonstrated that the proliferation of HCT116 cells was inhibited by OSR .

Synthesis and evaluation of 26-amino acid methyl ester substituted sarsasapogenin derivatives as neuroprotective agents for Alzheimer's disease.

Sarsasapogenin, extracted from Anemarrhena asphodeloides Bunge., has been reported to protect neurons from HO-induced damage. In the current study, four series of 26-amino acid methyl ester substituted sarsasapogenin derivatives (5a-5e, 5f-5j, 6a-6e and 7a-7e) were synthesized and tested for neuroprotective activity by evaluating their neuroprotective ratio against SH-SHY5Y cell lines.

[Effects of temperature and heating time on armco iron spectral emissivity in atmospheric environment].

The spectral emissivity of pure iron at 1.55 μm was investigated systematically by using our self-designed reflective experimental apparatus based on the Kirchhoff's law, and the influences of temperature and heating time on the spectral emissivity of pure iron were also discussed. The experimental data showed that the spectral emissivity of pure iron increased with temperature rising and its peak value and valley value appeared at certain temperatures.