Publications by authors named "Wen Yi"

Thermoelectrics have been limited by the scarcity of their constituent elements, especially telluride. The earth-abundant, wide-bandgap ( ≈ 46 ) tin sulfide (SnS) has shown promising performance in its crystal form. We improved the thermoelectric efficiency in SnS crystals by promoting the convergence of energy and momentum of four valance bands, termed quadruple-band synglisis.

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Aim: This study aimed to assess the relationship between compulsory citizenship behavior and nurses' silence.

Methods: A descriptive cross-sectional online study was conducted in October 2023, targeting 402 nurses working in Yichang Central People's Hospital, Hubei Province, China. Data were collected through a structured questionnaire comprising demographic details, the Compulsory Citizenship Behavior Scale, and the Nurses' Silence Scale.

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Pancreatic cancer is characterized by severe metabolic stress due to its prominent desmoplasia and poor vascularization. Integrin subunit alpha 3 (ITGA3) is a cell surface adhesion protein involved in tumor progression. However, the role of ITGA3 in pancreatic cancer progression, especially in metabolic reprogramming, remains largely unknown.

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  • * Current tests for measuring Lp(a) often assess total apo(a), which may not accurately reflect Lp(a) levels or the effects of new treatments.
  • * A new immunoassay developed for measuring Lp(a) particles showed better accuracy, indicating that muvalaplin's Lp(a)-lowering effects were previously underestimated by commercial tests, while lepodisiran's effects were consistent across both methods.
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Core fucosylation at N-glycans, which is uniquely catalyzed by fucosyltransferase FUT8, plays essential roles in post-translational regulation of protein function. Aberrant core fucosylation leads to neurological disorders in individuals with congenital glycosylation disorders (CDG). However, the underlying mechanisms for these neurological defects remain largely unknown.

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Arginine methylation of histones plays a critical role in regulating gene expression. The writers (methyltransferases) and readers of methylarginine marks are well-known, but the erasers-arginine demethylases-remain mysterious. Here we identify Myc-induced nuclear antigen 53 (Mina53), a jumonji C domain containing protein, as an arginine demethylase for removing asymmetric di-methylation at arginine 3 of histone H4 (H4R3me2a).

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  • The study focuses on accurately measuring ash, fixed carbon, and volatile matter in coal while accounting for the moisture content that affects the results.
  • Researchers used a method called PCA-PLS to analyze coal samples with moisture levels between 3% and 15% and found that higher moisture content increases prediction errors in the measurement models.
  • To improve accuracy, the team introduced an infrared CO laser technique to quickly dry moist coal samples, significantly reducing prediction errors and showcasing the method's potential for real-time detection in high-moisture coal environments.
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Maps are fundamental medium to visualize and represent the real word in a simple and philosophical way. The emergence of the big data tide has made a proportion of maps generated from multiple sources, significantly enriching the dimensions and perspectives for understanding the characteristics of the real world. However, a majority of these map datasets remain undiscovered, unacquired and ineffectively used, which arises from the lack of numerous well-labelled benchmark datasets, which are of significance to implement the deep learning techniques into identifying complicated map content.

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  • Epimedium plants, used in traditional Chinese medicine, faced a disease outbreak in August 2022, characterized by large necrotized leaf spots and fungal infections, leading to significant yield losses of over 20%.
  • Observations in Henan and Hubei provinces revealed the spread of white mycelia and sclerotia on infected plants, affecting 16.0% to 28.0% of the crops surveyed.
  • Laboratory analysis of symptomatic tissues resulted in the isolation of twelve fungal strains, which exhibited rapid growth and specific morphological characteristics indicative of their pathogenic potential.
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Persulfate-based advanced oxidation processes (PS-based AOPs), characterized by the coexistence of SO₄•⁻ and HO•, have been proven effective in treating a series of cyanide-bearing pollutants. However, the mechanisms of these reactive species in the degradation of cyanides, especially metal-cyanide complexes, remain unclear or contradictory. The degradation behavior of representative cyanides (including potassium cyanide and potassium ferricyanide) at different pH conditions (2, 7 and 12) in thermally activated persulfate system (T = 60 °C) was explored, and the roles of SO₄•⁻ and HO• in cyanide degradation were explored by leveraging the distinct characteristics of reactive species under different pH conditions.

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  • Aerobic glycolysis and immune evasion are important characteristics of cancer that are linked through the glycolytic enzyme enolase-1 (ENO1), which undergoes specific modifications known as O-GlcNAcylation.
  • Glycosylation at threonine 19 (T19) on ENO1 enhances its glycolytic function, while glycosylation at serine 249 (S249) inhibits its interaction with PD-L1, a protein that helps tumors evade the immune system.
  • Targeting the glycosylation of both sites on ENO1 can decrease tumor growth, improve immune response, and may enhance the effectiveness of PD-L1 monoclonal antibody therapy in treating colorectal cancers.
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  • ANGPTL3/4/8 proteins regulate lipoprotein lipase (LPL) activity, with ANGPTL8 forming complexes that influence ANGPTL4's function; however, their association with cardiovascular outcomes is under-researched.
  • This study involved measuring various ANGPTL proteins and complexes in two large population studies (LURIC and getABI) focusing on cardiovascular health and outcomes over several years.
  • Findings showed that while ANGPTL3/8 inhibited LPL activity and correlated with increased LDL-C and triglycerides, they did not predict cardiovascular death; however, ANGPTL4/8 and CD-ANGPTL4 were linked to higher diabetes prevalence and increased cardiovascular mortality risk.
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The COVID-19 pandemic and the International Maritime Organization's (IMO) 2020 fuel-switching policy have profoundly impacted global maritime activities, leading to unprecedented changes in shipping emissions. This study aimed to examine the effects from different scales and investigate the underlying drivers. The big data model Ship Emission Inventory Model (SEIM) was updated and applied to analyze the spatiotemporal pattern of global ship emissions as well as the main contributors in 2019 and 2020.

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  • Ideal thermoelectric materials should have a high average ZT, which is affected by carrier mobility and density; traditional doping techniques make it hard to optimize performance across different temperatures.
  • This study shows that combining lattice plainification with dynamic doping can significantly enhance the average ZT of N-type PbSe by improving carrier mobility and allowing for better control over carrier concentration.
  • The modified PbSe, incorporating both Sn and a small amount of Cu, achieves a maximum ZT of about 1.7 at 800 K and demonstrates a promising 7.7% power generation efficiency, making it a strong candidate for commercial use.
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Objectives: The coexistence of intrauterine twin pregnancy and ectopic pregnancy (EP), known as heterotopic pregnancy, is a rare but potentially life-threatening condition. In this study, we aimed to investigate the pregnancy outcomes in women with intrauterine twin pregnancies complicated with EP after assisted reproductive technology.

Methods: This retrospective study analyzed the medical records of 42 women diagnosed with intrauterine twin pregnancies complicated with EP via ultrasound or surgery at our hospital between January 2005 and December 2020.

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In recent years, the precision of exposure assessment methods has been rapidly improved and more widely adopted in epidemiological studies. However, such methodological advancement has introduced additional heterogeneity among studies. The precision of exposure assessment has become a potential confounding factors in meta-analyses, whose impacts on effect calculation remain unclear.

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  • Core fucosylation is an important protein modification involved in various biological processes, but existing detection methods lack specificity due to cross-reactivity with other fucosylations.
  • A new chemoenzymatic strategy has been developed that uses a specific galactosyltransferase enzyme to selectively target core fucosylated glycans for detection.
  • This method can detect core fucosylated glycoproteins from complex mixtures and live cells, making it useful for profiling protein-specific fucosylation levels and identifying disease biomarkers.
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  • Scientists have created a new method called UP-ChIP to study plants' DNA and how it's changed by environment.
  • It works better and is cheaper than the old method, ChIP-seq, and can use tiny amounts of plant samples.
  • UP-ChIP helps researchers learn about important DNA changes in different plant types, making it easier to see how plants grow and respond to their surroundings.
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Intradialytic hypotension (IDH) is common in hemodialysis patients and can lead to several complications. Risk factors for IDH include demographic characteristics, comorbidities, dialysis procedure factors, and so on. Clinical studies on predictive models for dialysis-induced hypotension have shown inconsistent results.

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  • A novel virus named "Rehmannia torradovirus virus" (ReTV) was identified in a crucial medicinal plant native to China, showing symptoms like mosaic patterns and leaf yellowing.
  • High-throughput sequencing techniques were used to obtain complete viral sequences, revealing substantial variations in amino acid alignments compared to known viruses.
  • ReTV was detected in all tested samples, indicating its potential risk to the plant and the need for ongoing monitoring in agricultural settings.
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  • The study looked at how ultrasound can help diagnose and treat a rare type of pregnancy called heterotopic intramural pregnancy (HIMP), where an embryo grows in the wall of the uterus after an embryo transfer.
  • Eight women were included in the study, and most were diagnosed correctly through ultrasound; many had successful pregnancies with healthy babies.
  • The researchers suggest that using only one embryo for transfer can lower the chance of getting HIMP, and that careful monitoring can help manage these pregnancies effectively.
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Head and neck cancer (HNC) is a highly aggressive type of tumor characterized by delayed diagnosis, recurrence, metastasis, relapse, and drug resistance. The occurrence of HNC were associated with smoking, alcohol abuse (or both), human papillomavirus infection, and complex genetic and epigenetic predisposition. Currently, surgery and radiotherapy are the standard treatments for most patients with early-stage HNC.

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  • This study examines the history and current pharmacological research of rhubarb, focusing on how various processing methods impact its active compounds, health effects, and possible toxicity, as well as its clinical uses.
  • The literature review utilized multiple databases to analyze terms related to rhubarb processing and its effects on health, highlighting the significance of traditional Chinese medicine and different rhubarb concoctions in treating diseases.
  • Findings reveal that rhubarb’s active compounds offer benefits such as anti-inflammatory and antibacterial properties, and specific concoctions can enhance therapeutic effects, which are rooted in traditional Chinese medicine principles, showcasing the evolving methods of rhubarb use from historical times to present.
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