Effects of Tratt on Ulcerative Colitis: An Integrated Analysis of Network Pharmacology and Experimental Validation.

Tratt is a traditional Chinese plant that has been used to treat different inflammatory diseases. The purpose of this study was to investigate the mechanism of action of Tratt extract (RRTE) against ulcerative colitis (UC) using network pharmacology and experimental validation. HPLC-Q/Orbitrap MS was used to rapidly identify the substances contained in RRTE after extracting the active components from the fruit.

[The Extract from Punica Granatum (Pomegranate) Leaves Promotes Apoptosis and Impairs Metastasis in Prostate Cancer Cells].

Objective: To investigate the effects of pomegranate leaves extract(PLE)on proliferation,apoptosis and metastasis of prostate cancer cells.

Methods: The proliferation of TRAMP-C1,DU145,PC3 prostate cancer cells treated with different concentrations of PLE (final mass concentrations were 12.5,25,50,100, 200 μg/mL,respectively) for different time (24,48,72 h) was detected by MTT assay.

[Determination of avermectin and ivermectin in swine muscular tissues using high performance liquid chromatography-tandem mass spectrometry].

Objective: To develop a method for simultaneous determination of avermectin (AVM) and ivermectin (IVM) in swine muscular tissues using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

Methods: The AVM and IVM were extracted with acetonitrile, cleaned with basic alumina solid phase extraction cartridges, separated through C8 column, and then detected by mass spectrometry in positive ion mode with multiple reaction monitoring (MRM) using an electrospray ionization interface, with quantitative ion pair of 890.4/305.

[A diabetic model for liver oxidant damage in mice].

Objective: To observe the liver oxidant damage for diabetic model in mice.

Methods: Male kunming mice were feed with high fat dietary for a week and then were randomly divided into two groups by weight, with 10 mice in each group. One group was induced by small dose streptozotocin (STZ) and obtained STZ-induced diabetic mice, and the other group was regarded as the control.

[Investigation of dietary fiber intakes and varies in 53 patients with diabetes].

Objective: To investigate the intakes of total dietary fiber (TDF), soluble dietary fiber (SDF) and insoluble dietary fiber (IDF) in Subjects With Type 2 Diabetes so as to provide the base for making the adequate intakes of dietary fiber.

Methods: The enzymatic-gravimetric methods for dietary fiber were established on basis of a collaborative study. Dietary intake was measured by means of 3-day food records through weighting and using food pictures.

[Analysis of lactase activities of small intestine mucous membrane by double labeled stable isotope technique in subjects with lactase deficiency].

Objective: Low lactase activity in small intestine mucosa is the main reason for the occurrence of lactose malabsorption (LM) and lactose intolerance (LI). It would be the basis for the research on LM and LI to find an accurate method to analyze the activity of lactase.

Methods: In this study, 43 volunteers were selected and divided into LM and LI group according to the results of H2 breath test and symptoms record.

Crystallographic and electrochemical characteristics of La(0.7)Mg(0.3)Ni(5.0-x)(Al(0.5)Mo(0.5)x hydrogen-storage alloys.

The structure, hydrogen-storage property and electrochemical characteristics of La(0.7)Mg(0.3)Ni(5.