Effects of triple semicircular canal plugging on hearing in patients with Meniere's disease: A systematic review and meta-analysis.

Introduction: Triple semicircular canal plugging is effective in controlling vertigo in patients with Meniere's disease, however, whether the rate of causing hearing loss during treatment is still not uniform. This study aimed to evaluate the effects of Triple semicircular canal plugging (TSCP) on hearing in Meniere's disease (MD) patients.

Methods: Databases Reviewed were PubMed, EMBASE, Scopus, Clinical Trials, Web of Science, Cochrane Library, CNKI, Wanfang, and VIP.

Superconductivity in an infinite-layer nickelate superlattice.

Recent observations of superconductivity in infinite-layer nickelates offer insights into high-temperature superconductivity mechanisms. However, defects and dislocations in doped films complicate the realization of superconductivity, limiting current research to superconducting nickelate heterostructures. The lack of research on superconductivity in superlattices composed of ultrathin nickelates severely impedes not only the exploration of the interface effect on superconductivity, but also the utilization of heterostructure engineering for exploring higher superconducting temperature T.

Bilateral Symmetric non-Euclidean multi-frequency invisibility.

Light propagation in non-Euclidean geometry has become a hot topic in recent years, while transformation optics theory demonstrates unique advantages in this respect. A notable application of transformation optics in non-Euclidean space is non-Euclidean invisibility cloak which avoids the challenges of negative refraction and anisotropic materials. In this work, we propose another configuration for non-Euclidean invisibility, capable of achieving invisible across a wide spectrum.

Photothermal-assisted S-scheme heterojunction of NiPS nanosheets modified ZnInS microspheres for promoting photocatalytic hydrogen evolution.

Exploring high-efficiency photocatalysts for solar hydrogen (H) generation through water splitting is of great significance for addressing both energy shortage and environmental contamination. In this work, a facile self-assembly strategy was developed to couple NiPS nanosheets (NPS NSs) with ZnInS (ZIS) microspheres to synthesize NPS NSs/ZIS (NPS/ZIS) composites, featuring a characteristic of S-scheme charge transfer mechanism. The NPS/ZIS composites possess broad-spectrum light absorption property, improved photothermal effect and efficient charge transfer, showcasing exceptional solar-to-chemical energy conversion capability for visible-light-driven photocatalytic hydrogen evolution (PHE).

Genetic characterization and selection of litter size traits of Guizhou Black goat and Meigu goat.

The aim of this study is to explore the genetic characteristics of Guizhou Black goats and Meigu goats and their relationship to reproductive performance through population structure analysis, genetic diversity assessment, and selection signal analysis. Blood samples of 19 Guizhou Black goats and 11 Meigu goats were collected for whole-genome high-throughput sequencing. Using PCA and ADMIXTURE analyses, their population structure and genetic relationships were revealed.

Comprehensive screening of industrially relevant components at genome scale using a high-quality gene overexpression collection of Corynebacterium glutamicum.

Development of efficient microbial strains for biomanufacturing requires deep understanding of the biology and functional components responsible for the synthesis, transport, and tolerance of the target compounds. A high-quality controllable gene overexpression strain collection was constructed for the industrial workhorse Corynebacterium glutamicum covering 99.7% of its genes.

Association between home literacy environment and eye movements during storybook reading: Implications for vocabulary and word reading in Chinese preschoolers.

This study explored the impact of different components of the Home Literacy Environment (HLE) -stimulation to use language, reading books and cultural engagement, joint activities and conversation, interactive reading, and zone-of-proximal development stimulation-on Chinese preschoolers' eye movements during storybook reading. Eighty-seven children aged 4-6 were assessed for vocabulary and word reading skills, while their eye movements were tracked during storybook reading. Their parents completed a questionnaire on personal background and frequency of HLE activities.

Nutrient responses of vascular plants to N-fixing tree Alnus hirsuta encroachment in a boreal peatland.

The N-fixing trees Alnus spp. have been widely encroaching into boreal peatlands, but the nutrient responses of native vascular plants remain unclear. Here, we compared nutrient concentrations and isotope signal of six common plants (Betula fruticosa, Salix rosmarinifolia, Vaccinium uliginosum, Rhododendron tomentosum, Chamaedaphne calyculata, and Eriophorum vaginatum) between Alnus hirsuta island and open peatland and assessed plant nutrient responses to A.

ZDHHC9-mediated Bip/GRP78 S-palmitoylation inhibits unfolded protein response and promotes bladder cancer progression.

Recent studies have highlighted palmitoylation, a novel protein post-translational modification, as a key player in various signaling pathways that contribute to tumorigenesis and drug resistance. Despite this, its role in bladder cancer (BCa) development remains inadequately understood. In this study, ZDHHC9 emerged as a significantly upregulated oncogene in BCa.

BIG coordinates auxin and SHORT ROOT to promote asymmetric stem cell divisions in Arabidopsis roots.

BIG regulates ground tissue formative divisions by bridging the auxin gradient with SHR abundance in Arabidopsis roots. The formative divisions of cortex/endodermis initials (CEIs) and CEI daughter cells (CEIDs) in Arabidopsis roots are coordinately controlled by the longitudinal auxin gradient and the radial SHORT ROOT (SHR) abundance. However, the mechanism underlying this coordination remains poorly understood.

Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y Receptor Antagonists for Inflammatory Bowel Disease Treatment.

The P2Y receptor has been proven to be a potential target for IBD. Herein, we designed and synthesized a series of 4-amide-thiophene-2-carboxyl derivatives as novel potent P2Y receptor antagonists based on the scaffold hopping strategy. The optimized compound (5-((5-fluoropyridin-2-yl)oxy)-4-(4-methylbenzamido)thiophene-2-carboxylic acid) exhibited subnanomolar antagonistic activity (IC: 0.

Urea regulates soil nematode population by enhancing the nematode-trapping ability of nematode-trapping fungi.

As the most abundant animal in the soil, nematodes are directly or indirectly involved in almost all soil ecological processes. Studying soil nematode population regulation is essential to understanding soil ecological processes. This study found urea combines nematode-trapping fungi to regulate the population of soil nematodes.

Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.

Background: Bacterial infections pose a considerable threat to skin wounds, particularly in the case of challenging-to-treat diabetic wounds. Systemic antibiotics often struggle to penetrate deep wound tissues and topically applied antibiotics may lead to sensitization, necessitating the development of novel approaches for effectively treating germs in deep wound tissues. Neutrophils, the predominant immune cells in the bloodstream, rapidly release an abundance of molecules via degranulation upon activation, which possess the ability to directly eliminate pathogens.