Publications by authors named "Wen Leng"

Objective: To observe the therapeutic effect of scalp acupuncture on cognitive dysfunction of traumatic brain injury.

Methods: Seventy patients with cognitive dysfunction of traumatic brain injury were randomly divided into an observation group and a control group, 35 cases in each group. After treatment, 5 cases dropped off in each group.

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This paper addresses the two-dimensional (2D) direction-of-arrival (DOA) estimation problem with two novel methods for mixed noncircular and circular signals. The first proposed method is named the two-stage direction-of-arrival matrix (TSDOAM) method, and the other is called the two-stage rank reduction (TSRARE) method. The proposed methods utilize both the circularity and the direction-of-arrival differences between the noncircular and circular sources to estimate the 2D directions-of-arrival (DOAs).

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Glutamate neurotoxicity is one of the causative factors leading to neural degeneration including retina. Inhibition of NMDA receptors has been shown neuroprotective effects. However, specifically inhibition of glycine subunit in NMDA receptors and its effects on retina neural protection has not been tested.

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We recently identified TL1A, an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3. To elucidate the signaling events triggered by TL1A-DR3 interaction and to understand the molecular mechanisms regulating DR3-mediated apoptosis, we have studied the effect of TL1A and an agonistic DR3 monoclonal antibody in human erythroleukemic TF-1 cells, which express DR3 endogenously. TL1A induced the formation of a DR3 signaling complex containing TRADD, TRAF2, and RIP and activated the NF-kappaB and the ERK, JNK, and p38 mitogen-activated protein kinase pathways.

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