Publications by Welwyn Cotta

Publications by authors named "Welwyn Cotta"

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Conditional disruption of Axin1 leads to development of liver tumors in mice.

Gui Jie Feng Welwyn Cotta Xiao Qing Wei Oliver Poetz Rebecca Evans

Gastroenterology

December 2012

Background & Aims: Mutations in components of the Wnt signaling pathway, including β-catenin and AXIN1, are found in more than 50% of human hepatocellular carcinomas (HCCs). Disruption of Axin1 causes embryonic lethality in mice. We generated mice with conditional disruption of Axin1 to study its function specifically in adult liver.

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