Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy: a propensity score-weighted matching approach.

The study purpose was to assess the relationship between various grades of preterm birth (moderate preterm: 33-36 weeks; severe preterm: 27-32 weeks; extreme preterm: ≤ 26 weeks) in the first pregnancy and neonatal mortality (death within 28 days of birth; early: 0-7 days; late: 8-28 days) in the second pregnancy. Using the Missouri maternally-linked dataset (1989-2005), a population-based, retrospective cohort analysis with propensity score-weighted matching was conducted on mothers with two consecutive singleton live births (n = 310,653 women). Women with a prior preterm birth were more likely to subsequently experience neonatal death.

All-cause infant mortality and the risk for subsequent preterm birth.

Aim: The aim of this paper was to assess the association between all-cause infant mortality (death<365 days) in the first pregnancy and the risk of preterm birth (<37 weeks of gestation) in the second pregnancy.

Methods: Using the Missouri maternally linked dataset from 1989 to 2005 (N.=639134 singleton live births), we conducted a population-based retrospective cohort analysis with women who had two singleton births between 1989 and 2005.

Impact of sickle cell disease and thalassemias in infants on birth outcomes.

Objective: The contribution of sickle cell disease (SCD) and other common thalassemias in infants to adverse birth outcomes is under-studied. We therefore sought to compare adverse birth outcomes in infants with and without hemoglobinopathy.

Study Design: Retrospective cohort study utilizing a population-based dataset from Florida (1998-2007, n=1,564,038).

The association between female genital mutilation and intimate partner violence.

Objective: To determine whether female genital mutilation (FGM) is a risk factor for intimate partner violence (IPV) and its subtypes (physical, sexual and emotional).

Design: Population-based cross-sectional study.

Setting: The study used the 2006 Demographic and Health Survey (DHS) conducted in Mali.

Small size for gestational age and the risk for infant mortality in the subsequent pregnancy.

Purpose: To examine the association between small for gestational age (SGA) in the first pregnancy and risk for infant mortality in the second pregnancy.

Methods: This is a population-based, retrospective cohort study in which we used the Missouri maternally linked cohort dataset for 1978-2005. Analyses were restricted to women who had two singleton pregnancies during the study period.

Infant mortality and the risk of small size for gestational age in the subsequent pregnancy: a retrospective cohort study.

To examine the association between prior infant mortality and subsequent risk for small for gestational age (SGA). This population-based, retrospective cohort study used the Missouri maternally linked, longitudinal dataset (1989-2005). Analyses were restricted to women who had two singleton pregnancies during the study period.

The association between HIV/AIDS during pregnancy and fetal growth parameters in Florida: a population based study.

In this population-based retrospective study, we sought to investigate the association between HIV/AIDS during pregnancy and adverse birth outcomes, including low birth weight (LBW), very low birth weight (VLBW), preterm birth (PTB), very preterm birth (VPTB), and small for gestational age (SGA), among women in Florida by sociodemographic variables. Using data from Florida's maternally linked birth cohort files, we examined singleton live births in the state during 1998 to 2007 (N = 1,698,107). The study population was categorized based on the maternal HIV/AIDS status.

Cigarette smoking and fetal morbidity outcomes in a large cohort of HIV-infected mothers.

Background: Reproductive-age women comprise approximately 25% of all persons living with HIV/AIDS in the United States. HIV infection and smoking during pregnancy are independent risk factors for adverse fetal outcomes. We examined predictors of fetal growth restriction among infants born to HIV-infected mothers who smoke cigarettes in pregnancy.

The effect of paternal age on fetal birth outcomes.

Research investigating the role of paternal age in adverse birth outcomes is limited. This population-based retrospective cohort study used the Missouri maternally linked data set from 1989 to 2005 to assess whether paternal age affects fetal birth outcomes: low birth weight (LBW), preterm birth (PTB), stillbirth, and small size for gestational age (SGA). We examined these outcomes among infants across seven paternal age-groups (<20, 20-24, 25-29, 30-34, 35-39, 40-45, and >45 years) using the generalized estimating equation framework.

Impact of prior bariatric surgery on maternal and fetal outcomes among obese and non-obese mothers.

Purpose: To assess the association between bariatric surgery and pregnancy-related outcomes among obese and non-obese women in the state of Florida.

Methods: We conducted a population-based, retrospective cohort analysis using vital records and hospital discharge data in Florida during 2004-2007. Women were categorized based on prior bariatric surgery and pre-pregnancy obesity status.

Prevalence and temporal trends of hepatitis B, hepatitis C, and HIV/AIDS co-infection during pregnancy across the decade, 1998-2007.

Background: Limited data are available on hepatitis rates during pregnancy by socio-demographic characteristics. This study examined temporal trends in hepatitis B virus (HBV) and hepatitis C virus (HCV) mono-infections and HIV/HBV and HIV/HCV co-infections in subpopulations among pregnant women in Florida between 1998 and 2007.

Methods: We analyzed all Florida live births from 1998 to 2007 using hospital discharge data linked to birth records.

Infant mortality and subsequent risk of stillbirth: a retrospective cohort study.

Objective: To examine the association between infant mortality in a first pregnancy and risk for stillbirth in a second pregnancy.

Design: Population-based, retrospective cohort study.

Setting: Maternally linked cohort data files for the state of Missouri.

Neonatal outcomes of successful VBAC among obese and super-obese mothers.

Objective: We sought to evaluate neonatal morbidity and mortality among women who experienced successful vaginal births after previous cesarean delivery (VBAC) by obesity subtypes.

Methods: Missouri maternally linked cohort data files were utilized. Analyses were restricted to successful singleton VBACs.

Temporal trends in cardiomyopathy in pregnancy and association with feto-infant morbidity outcomes.

Objective: To examine temporal trends of cardiomyopathy in pregnancy and its association with feto-infant morbidity outcomes.

Design And Methods: We performed a population-based retrospective cohort analysis utilizing the Florida hospital discharge data linked to vital statistics for 1998 to 2007 (N = 1 738 860). Prevalence rates and trend statistics of cardiomyopathy were computed.

Maternal hepatitis B and hepatitis C carrier status and perinatal outcomes.

Background And Aims: To examine the association between maternal hepatitis B and C mono- and co-infections with singleton pregnancy outcomes in the state of Florida.

Methods: We analysed all Florida births from 1998 to 2007 using birth certificate records linked to hospital discharge data. The main outcomes of interest were selected pregnancy outcomes including preterm birth, low birth weight (LBW), small for gestational age (SGA), fetal distress, neonatal jaundice and congenital anomaly.

Stillbirth as a risk factor for subsequent infant mortality.

Background: Infant mortality is an important indicator of the health and wellness of a society. Multiple risk factors for infant mortality have been identified and investigated; however, the influence of prior pregnancy experience on subsequent infant mortality is under-researched.

Aims: To examine the association between stillbirth in the first pregnancy and risk for infant mortality in the second pregnancy in a large population-based dataset.

Maternal HIV/AIDS status and neurological outcomes in neonates: a population-based study.

This study sought to examine the association between maternal HIV/AIDS infection and neonatal neurologic conditions in the state of Florida. We analyzed all births in the state of Florida from 1998 to 2007 using hospital discharge data linked to birth certificate records. The main outcomes of interest included selected neonatal neurologic complications, namely: fetal distress, cephalohematoma, intracranial hemorrhage, seizure, feeding difficulties, and other central nervous system complications.

The impact of obesity on maternal morbidity and feto-infant outcomes among macrosomic infants.

Objective: To estimate the contribution of obesity to maternal complications, neonatal morbidity and mortality among macrosomic births.

Design: A population-based retrospective cohort design using State of Missouri maternally linked birth cohort files.

Methods: Using pre-gravid body mass index (BMI), we categorized mothers of 116,976 singleton macrosomic live births as non-obese (BMI < 30) or obese (BMI ≥ 30).