Association of Di(2-ethylhexyl) Phthalate Exposure with Reproductive Hormones in the General Population and the Susceptible Population: A Systematic Review and Meta-Analysis.

Di(2-ethylhexyl) phthalate (DEHP), an environmental endocrine disruptor, has hormone-like activity and endocrine-disrupting effects. However, the types of reproductive hormones associated with DEHP vary across the studies. Thus, we conducted a systematic review and meta-analysis to pool existing epidemiological evidence.

Effects of PM and Its Components on Disease Severity in Patients with Schizophrenia and the Mediating Role of Thyroid Hormones.

Studies have indicated the different effects of PM components on human health. However, specific components that influence the severity of disease in schizophrenia patients and their underlying mechanisms remain unclear. Therefore, a repeated measures study for schizophrenia was constructed based on Anhui Mental Health Center.

Quantifying the historical and future heat-related mortality above the heat alert thresholds of the inaugural Chinese national heat-health action plan.

Background: China published its inaugural national heat-health action plan (HHAP) in 2023, but the mortality burden associated with temperatures exceeding the heat alert thresholds specified by this HHAP (maximum temperatures >35, 37, or 40 °C) remains unknown. We aimed to estimate the historical and future mortality burden associated with temperatures above the heat alert thresholds of the Chinese national HHAP.

Methods: We conducted time-series analyses to estimate the mortality burden associated with temperatures exceeding the three heat alert thresholds from 2016 to 2019 in Jiangsu Province (including 13 cities, population ∼80.

Extreme temperatures, PM and trajectories of impaired thyroid hormone sensitivity: A longitudinal study of patients with schizophrenia.

Background: The climate change scenario has witnessed an increase in extreme temperature events (ETEs), including heat waves and cold spells, and a heightened occurrence of compounding with fine particulate matter (PM). However, the impact of this phenomenon on the sensitivity to thyroid hormones (THs) in humans is unclear, especially in a group as specific as schizophrenia.

Methods: A longitudinal study was constructed using longitudinal measurements of thyroid function in schizophrenia in the Anhui Mental Health Center.

Effects of socioeconomic status and regional inequality on the association between PM and its components and cardiometabolic multimorbidity: A multicenter population-based survey in eastern China.

Background: Despite evidence linking fine particulate matter (PM) to cardiometabolic multimorbidity (CMM), the impact of its components remains unclear. Socioeconomic status (SES) and regional disparities may confound their association. We aim to evaluate the associations between PM components and CMM and explore how socioeconomic status and regional disparities affect these relationships.

Impaired thyroid hormone sensitivity exacerbates the effect of PM and its components on dyslipidemia in schizophrenia.

Background: Dyslipidemia in schizophrenia causes a serious loss of healthy life expectancy, making it imperative to explore key environmental risk factors. We aimed to assess the effect of PM and its constituents on dyslipidemia in schizophrenia, identify the critical hazardous components, and investigate the role of impaired thyroid hormones (THs) sensitivity in this association.

Methods: We collected disease data on schizophrenia from the Anhui Mental Health Center from 2019 to 2022.

Does the morphology of residential greenspaces contribute to the development of a cardiovascular-healthy city?

Backgrounds: Greenspaces are indispensable for the construction of a healthy city. Research has shown that greenspaces contribute to the reduction of cardiovascular risks. However, the role of greenspace morphology in the development of a healthy city is not well understood.

Multimorbidity and emergency hospitalisations during hot weather.

Background: People with chronic diseases are a commonly listed heat-vulnerable group in heat-health action plans. While prior research identifies multiple health conditions that may increase vulnerability to ambient heat, there is minimal evidence regarding the implications of multimorbidity (two or more chronic diseases).

Methods: From the statewide hospital registry of Queensland, Australia, we identified people aged ≥15 years who had emergency hospitalisation(s) between March 2004 and April 2016 and previously had 0, 1, 2, or ≥3 of five chronic diseases: cardiovascular disease, diabetes, mental disorders, asthma/COPD, and chronic kidney disease.

Heatwave characteristics complicate the association between PM components and schizophrenia hospitalizations in a changing climate: Leveraging of the individual residential environment.

Background: In the era characterized by global environmental and climatic changes, understanding the effects of PM components and heatwaves on schizophrenia (SCZ) is essential for implementing environmental interventions at the population level. However, research in this area remains limited, which highlights the need for further research and effort. We aim to assess the association between exposure to PM components and hospitalizations for SCZ under different heatwave characteristics.

Green space and its types can attenuate the associations of PM and its components with prediabetes and diabetes-- a multicenter cross-sectional study from eastern China.

Background: The effect of fine particulate matter (PM) components on prediabetes and diabetes is of concern, but the evidence is limited and the specific role of different green space types remains unclear. This study aims to investigate the relationship of PM and its components with prediabetes and diabetes as well as the potential health benefits of different types and combinations of green spaces.

Methods: A multicenter cross-sectional study was conducted in eastern China by using a multi-stage random sampling method.

A systematic analysis of chronic kidney disease burden attributable to lead exposure based on the global burden of disease study 2019.

Aim: As an important toxic heavy metal, lead exposure can lead to the occurrence of chronic kidney disease (CKD). However, the analysis of its disease burden pattern on a global scale is lacking. This study aimed to analyze the CKD burden attributable to lead exposure globally, regionally and temporally, as well as to examine the role of socio-economic factors.

Association of outdoor artificial light at night with metabolic syndrome and the modifying effect of tree and grass cover.

Background: Epidemiological studies show that outdoor artificial light at night (ALAN) is linked to metabolic hazards, but its association with metabolic syndrome (MetS) remains unclear. We aimed to investigate the association of outdoor ALAN with MetS in middle-aged and elderly Chinese.

Methods: From 2017-2020, we conducted a cross-sectional study in a total of 109,452 participants living in ten cities of eastern China.

Association between ambient air pollution and thyroid hormones levels: A systematic review and meta-analysis.

Background: Growing studies have focused on the effects of ambient air pollution on thyroid hormones (THs), but the results were controversial. Therefore, a systematic review and meta-analysis was conducted by pooling current evidence on this association.

Methods: Four databases were searched for studies examining the associations of particulate matter [diameter ≤10 μm (PM) or ≤2.

The association between greenery type and gut microbiome in schizophrenia: did all greenspaces play the equivalent role?

In recent years, attention has been focused on the benefit of greenspace on mental health, and it is suggested this link may vary with the type of greenspace. More and more studies have emphasized the influence of the gut microbiome on schizophrenia (SCZ). However, the effects of greenspaces on the gut microbiota in SCZ and the effect of different types of greenspaces on the gut microbiota remain unclear.

The ratio of monocyte count and high-density lipoprotein cholesterol mediates the association between urinary tungsten and cardiovascular disease: a study from NHANES 2005-2018.

Tungsten (W) is an emerging contaminant that can damage multiple systems in humans. However, studies of its effects on cardiovascular disease (CVD) are limited. The monocyte count to high-density lipoprotein cholesterol ratio (MHR) is a composite inflammatory index of great concern in recent years, derived from lipid and cell inflammation parameters, that is used to indicate the risk of CVD.

Characterization of airborne microplastics at different workplaces of the poly(ethylene:propylene:diene) (EPDM) rubber industry.

Microplastics (MPs) as an emerging air pollutant have received widespread attention, but research on airborne MPs at occupational sites is still limited, especially in the rubber industry. Hence, indoor air samples were collected from three production workshops and an office of a rubber factory producing automotive parts to analyze the characteristics of airborne MPs in different workplaces of this industry. We found MP contamination in all air samples from the rubber industry, and the airborne MPs at all sites mainly showed small-sized (< 100 μm) and fragmented characteristics.

The global burden of schizophrenia and the impact of urbanization during 1990-2019: An analysis of the global burden of disease study 2019.

Background And Hypothesis: The burden of schizophrenia is increasing. Assessing the global distribution of schizophrenia and understanding the association between urbanization factors and schizophrenia are crucial.

Study Design: We conducted a two-stage analysis utilizing public data from GBD (global burden of disease) 2019 and the World Bank.

Built environment and schizophrenia re-hospitalization risk in China: A cohort study.

Background: Built environment exposure, characterized by ubiquity and changeability, has the potential to be the prospective target of public health policy. However, little research has been conducted to explore its impact on schizophrenia. This study aimed to investigate the association between built environmentand and schizophrenia rehospitalization by simultaneously considering substantial built environmental exposures.

Association of PM Components with Acceleration of Aging: Moderating Role of Sex Hormones.

Fine particulate matter (PM) has been linked to aging risk, and a lack of knowledge about the relationships between PM components and aging risk impeded the development of healthy aging. Participants were recruited through a multicenter cross-sectional study in the Beijing-Tianjin-Hebei region in China. Middle-age and older males and menopausal women completed the collection of basic information, blood samples, and clinical examinations.

Sunshine duration and risks of schizophrenia hospitalizations in main urban area: Do built environments modify the association?

Background: Although studies have explored the relationship between sunshine duration and schizophrenia, the evidence was ambiguous. Different built environments may alter the effect of sunlight on schizophrenia, thus the purpose of this study was to investigate the effects of built environments on the sunshine duration-schizophrenia association.

Materials And Methods: Daily schizophrenia hospitalizations data during 2017-2020 in Hefei's main urban area, China, and corresponding meteorological factors as well as ambient pollutants were collected.

Phenotypic aging mediates the association between blood cadmium and depression: a population-based study.

Depression is a serious public health problem today, especially in middle-aged and older adults. Although the etiology of the disease has not been fully elucidated, environmental factors are increasingly not negligible. Cadmium is widely used in industrial production.

Associations of polycyclic aromatic hydrocarbons, water-soluble ions and metals in PM with liver function: Evidence from schizophrenia cohort.

Background: Fine particulate matter (PM) was reported to impact liver function, but the roles of specific PM chemical components remained to be explored. Besides, severe liver dysfunction in schizophrenia patients deserves attention.

Objective: To investigate the associations of short-term PM components with liver function in schizophrenia patients.

Premature mortality attributable to NO exposure in cities and the role of built environment: A global analysis.

Background: Environmental risks accumulate in cities, including polluted air and health disparities, but these risks can be reduced through scientific city planning. The purpose of this study was to investigate the global burden of premature mortality attributable to NO exposure in urban areas and the role of the built environment in this regard.

Methods: An approach based on health impact assessment was used to estimate the premature mortality burdens associated with NO exposure in 13,169 urban areas around the world using globally gridded NO and population estimates, baseline mortality, and epidemiologically derived exposure-response functions.

The impact of hazes on schizophrenia admissions and the synergistic effect with the combined atmospheric oxidation capacity in Hefei, China.

Objectives: Currently, most epidemiological studies on haze focus on respiratory diseases, cardiovascular diseases, etc. However, the relationship between haze and mental health has not been adequately explored. The purpose of this study was to investigate the influence of hazes on schizophrenia admissions and to further explore the potential interaction effect with the combined atmospheric oxidative indices (O and O).