Effect of biodegradable microplastics and Cd co-pollution on Cd bioavailability and plastisphere in soil-plant system.

Biodegradable plastics (BPs) are regarded as ecomaterials and are emerging as a substitute for traditional non-degradable plastics. However, the information on the interaction between biodegradable microplastics (BMPs) and cadmium (Cd) in agricultural soil is still limited. Here, lettuce plants were cultured in BMPs (polylactic acid (PLA) MPs and poly(butylene-adipate-co-terephthalate) (PBAT) MPs) and Cd co-polluted soil for 35 days.

Effects of Decabromodiphenyl Ethane and Cadmium Coexposure on Their Bioaccumulation, Oxidative Stress, Root Metabolism, and Rhizosphere Soil Microorganisms in a Soil-Rice System.

Decabromodiphenyl ethane (DBDPE) and cadmium (Cd) are typical pollutants in e-waste, seriously threatening crop growth. This study investigated the bioaccumulation and toxicity mechanisms of DBDPE and Cd in a soil-rice system. The results showed that 50 mg/kg DBDPE could reduce the level of accumulation of Cd in rice roots.

Chitosan-Copper Hybrid Nanoflowers: A Novel Nanopesticide for Controlling Infection in Crops.

Copper-based nanomaterials are effective alternatives to traditional pesticides due to their antibacterial properties. However, the high cost and low dispersity limit their application. In this study, we synthesized cost-effective, eco-friendly, and stable chitosan-copper hybrid nanoflowers (CS-Cu HNFs) through facile self-assembly to manage agricultural diseases caused by the fungal pathogen ().

Huang-Jin-Shuang-Shen Decoction promotes CD8+ T-cell-mediated anti-tumor immunity by regulating chemokine CXCL10 in gastric cancer.

Background: Research on immunotherapy for gastric cancer is currently receiving significant attention, with particular emphasis on the role of CD8+ T cells in anti-tumor immune responses. In recent years, the importance of the chemokine CXCL10 in promoting anti-tumor immunity has been increasingly recognized because it plays a crucial role in recruiting CD8+ T cells to the tumor microenvironment. The Huang-Jin-Shuang-Shen (HJSS) Decoction, a Chinese medicine, has been used as an adjuvant drug for gastric cancer chemotherapy.

Causal relationship between depression and metabolic dysfunction-associated steatotic liver disease: a bidirectional Mendelian randomized study.

Background: With the global rise in obesity, metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common chronic liver disease. Concurrently, depression is a highly prevalent mental disorder. As the incidence of MASLD and depression continues to increase, a growing body of research indicates a potential association between the two conditions.

Causal associations between estradiol and mouth ulcers: A Mendelian randomization study.

People have difficulty in eating and speaking when they are suffering from mouth ulcers. Some studies suggest that estradiol is associated with the development and treatment of mouth ulcers, while some do not. To clarify the effect of estradiol on mouth ulcers, we performed 2-sample Mendelian randomization and multivariable Mendelian randomization (MVMR) analysis to evaluate their relationship.

Nonalcoholic Fatty Liver Disease: Changes in Gut Microbiota and Blood Lipids.

Background And Aims: The global prevalence of nonalcoholic fatty liver disease (NAFLD) is 25%. This study aimed to explore differences in the gut microbial community and blood lipids between normal livers and those affected by NAFLD using 16S ribosomal deoxyribonucleic acid sequencing.

Methods: Gut microbiome profiles of 40 NAFLD and 20 non-NAFLD controls were analyzed.

[Baicalin induces ferroptosis in HepG2 cells by inhibiting ROS-mediated PI3K/Akt/FoxO3a signaling pathway].

This study aims to investigate whether baicalin induces ferroptosis in HepG2 cells and decipher the underlying mechanisms based on network pharmacology and cell experiments. HepG2 cells were cultured in vitro and the cell viability was detected by the cell counting kit-8(CCK-8). The transcriptome data of hepatocellular carcinoma were obtained from the Cancer Genome Atlas(TCGA), and the ferroptosis gene data from FerrDb V2.

Copper-based nanomaterials: Opportunities for sustainable agriculture.

The exponential growth of the global population has resulted in a significant surge in the demand for food worldwide. Additionally, the impact of climate change has exacerbated crop losses caused by pests and pathogens. The transportation and utilization of traditional agrochemicals in the soil are highly inefficient, resulting in significant environmental losses and causing severe pollution of both the soil and aquatic ecosystems.

Organic matters adsorbed on goethite inhibited the heterogeneous aggregation and adsorption of CdSe quantum dots: Experiments and extended DLVO theory.

The widespread use of Cd-based quantum dots (Cd-QDs) has led to their inevitable release into the environment, and the prevalent iron oxides and natural organic matter (NOM) are the key factors affecting the environmental behavior and fate of Cd-QDs. However, the impact of NOM adsorbed on iron oxides on the behavior of Cd-QDs with iron oxides and the mechanism of its interaction are not clear. In this study, two kinds of water-soluble QDs (CdSe QDs and core-shell CdSe/ZnS QDs) were selected to study the aggregation and adsorption behavior on goethite (Goe) and goethite-humic acid/fulvic acid composites (Goe-HA/FA).

Beta-elemene: A phytochemical with promise as a drug candidate for tumor therapy and adjuvant tumor therapy.

Background: β-Elemene (IUPAC name: (1 S,2 S,4 R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl) cyclohexane), is a natural compound found in turmeric root. Studies have demonstrated its diverse biological functions, including its anti-tumor properties, which have been extensively investigated. However, these have not yet been reviewed.

Megafossils of Betulaceae from the Oligocene of Qaidam Basin and their paleoenvironmental and phytogeographic implications.

Understanding the paleoenvironment and phytogeographical history of the Tibetan Plateau, China relies on discovering new plant fossils. The Qaidam Basin has long been regarded as an ideal 'field laboratory' to investigate the paleoclimate and paleobiological evolution of the northern Tibetan Plateau. However, fossil angiosperms from the Qaidam Basin are rare, and our knowledge of its paleovegetation is poor.

Regulator of G protein signaling 1 is a potential target in gastric cancer and impacts tumor-associated macrophages.

Regulator of G protein signaling 1 (RGS1) is closely associated with the tumor immune microenvironment and is highly expressed in various tumors and immune cells. The specific effects of RGS1 in the dynamic progression from chronic gastritis to gastric cancer have not been reported, and the role of tumor-associated macrophages (TAMs) is also unclear. In the present study, RGS1 was identified as an upregulated gene in different pathological stages ranging from chronic gastritis to gastric cancer by using Gene Expression Omnibus (GEO) screening together with pancancer analysis of The Cancer Genome Atlas and clinical prognostic analysis.

Applications and synergistic degradation mechanisms of nZVI-modified biochar for the remediation of organic polluted soil and water: A review.

Increasing organic pollution in soil and water has garnered considerable attention in recent years. Nano zero-valent iron-modified biochar (nZVI/BC) has been proven to remediate the contaminated environment effectively due to its abundant active sites and unique reducing properties. This paper provides a comprehensive overview of the application of nZVI/BC in organic polluted environmental remediation and its mechanisms.

Appendicitis in pregnant women: A systematic review and meta-analysis of the diagnostic performance of ultrasonography.

Objectives: The accuracy of ultrasound in the detection of appendicitis in pregnant women was examined in a meta-analysis.

Methods: Pregnant women with suspected acute appendicitis were evaluated using ultrasound in a systematic search of PubMed, EMBASE, and Cochrane Library databases from January 1, 2011 to August 10, 2023. The sensitivity and specificity values and diagnostic odds ratios were obtained using the pooled data.

Stabilization of Ni by rhamnolipid modified nano zero-valent iron in soil: Effect of simulated acid rain and microbial response.

Nickel (Ni), as one of the essential micronutrients, exists widely in nature, but high concentration of Ni in soil can pose certain biological toxicity. Nano zero-valent iron (nZVI) and rhamnolipid modified nZVI (RL@nZVI) can effectively stabilize Ni in soil. In this study, the stabilization effect of nZVI and RL@nZVI on the Ni-polluted soil under simulated acid rain and the microbial community response during the soil remediation under different Ni levels (200, 600, and 1800 mg/kg) were investigated.

Contamination characteristics and potential health risk of brominated flame retardants in paddy soils and rice plants around a typical e-waste recycling site in south China.

Brominated flame retardants (BFRs) are widely used in various productions. As typical BFRs, polybrominated diphenyl ethers (PBDEs) are prohibited because of their toxicity and persistence. Some of the alternatives to PBDEs, new brominated flame retardants (NBFRs), have also been found in the environment and some have assigned hazardous properties and were categorized as persistent.

Harnessing the power of collective intelligence in dentistry: a pilot study in Victoria, Australia.

Background: In many dental settings, diagnosis and treatment planning is the responsibility of a single clinician, and this process is inevitably influenced by the clinician's own heuristics and biases. Our aim was to test whether collective intelligence increases the accuracy of individual diagnoses and treatment plans, and whether such systems have potential to improve patient outcomes in a dental setting.

Methods: This pilot project was carried out to assess the feasibility of the protocol and appropriateness of the study design.

Effect of polyethylene, polyamide, and polylactic acid microplastics on Cr accumulation and toxicity to cucumber (Cucumis sativus L.) in hydroponics.

Microplastics (MPs) in farmland soil may affect the environmental fate and toxicity of heavy metals; however, how non-biodegradable and biodegradable MPs change the accumulation and phytotoxicity of Cr(VI) to the plants is still unknown. In this study, we explored the impacts of Cr(VI) concentrations (0, 20, 50, 100, 200, and 500 μmol/L), MP types (polyethylene (PE), polyamide (PA), and polylactic acid (PLA)), sizes (13, 48, and 500 µm), and concentrations (40, 200, and 1000 mg/L) on the Cr accumulation and toxicity to cucumber (Cucumis sativus L.) under hydroponic conditions for 14 days.

Polyamide microplastics as better environmental vectors of Cr(VI) in comparison to polyethylene and polypropylene microplastics.

The adsorption, desorption, and their influence factors of Cr(VI) by microplastics (MPs) in the solution was investigated in this study. The results demonstrated that UV aging promoted adsorption, while the increase of salinity and natural organic matter (NOM) inhibited adsorption. The particle size affected the total Cr(VI) active adsorption sites on MPs, while the pH changed the electrostatic force.

Simultaneous immobilization of arsenic, lead, and cadmium in soil by magnesium-aluminum modified biochar: Influences of organic acids, aging, and rainfall.

Magnesium-aluminum modified biochar (MABs) has an outstanding effect on the simultaneous immobilization of arsenic (As), lead (Pb), and cadmium (Cd) in soil, but the stability of remediation effect of MAB under various natural conditions is still unknown. In this study, we investigated the effects of organic acids, dry-wet cycles (DW), freeze-thaw cycles (FT), and rainfall (pH 4, 7, and 8) on the immobilization of As, Pb, and Cd by MAB. The results showed that oxalic acid decreased the immobilization efficiencies of As, Pb, and Cd by 15.

Simultaneous stabilization of Pb, Cd, and As in soil by rhamnolipid coated sulfidated nano zero-valent iron: Effects and mechanisms.

Sulfidation effectively improves the electron transfer efficiency of nanoscale zero-valent iron (nZVI), but decreases the specific surface area of nZVI. In this study, sulfidated nZVI (S-nZVI) coated with rhamnolipid (RL-S-nZVI) was synthesized and used to stabilize Pb, Cd, and As in combined polluted soil. The stabilization efficiency of 0.

Exogenous iron alters uptake and translocation of CuO nanoparticles in soil-rice system: A life cycle study.

The abundant iron in farmland soil may affect the environmental fate of metal-based nanoparticles (MNPs). In this study, the effect of FeSO and nano-zero-valent iron (nZVI) as exogenous iron on the uptake and translocation of CuO nanoparticles (NPs) in soil-rice system was performed in a life cycle study. The results show that exogenous iron basically elevated the soil pH and electrical conductivity but lowered the redox potential.

A comparative and modeled approach for three biochar materials in simultaneously preventing the migration and reducing the bioaccessibility of heavy metals in soil: Revealing immobilization mechanisms.

The effectiveness and feasibility of the three biochar materials for remediation of arsenic (As) and lead (Pb) contaminated soil were explored in this study. Significant reduction of bioaccessibility and migration risks of both heavy metals have been explained mechanistically by incubation, column experiments and numerical simulation. Langmuir equation fitted As and Pb sorption isotherms better in the control and biochar (BC) amended soils, while Freundlich model was more suitable for iron modified biochar (Fe-BC) and sulfur/iron modified biochar (S/Fe-BC) amended soils, indicating that modified biochar promoted chemical adsorption process for As and Pb.