Ecotoxicology of microplastics in Daphnia: A review focusing on microplastic properties and multiscale attributes of Daphnia.

The ubiquitous presence of microplastics in aquatic environments is considered a global threat to aquatic organisms. Species of the genus Daphnia provide an important link between aquatic primary producers and consumers of higher trophic levels; furthermore, these organisms exhibit high sensitivity to various environmental pollutants. Hence, the biological effects of microplastics on Daphnia species are well documented.

Microplastics can affect the trophic cascade strength and stability of plankton ecosystems via behavior-mediated indirect interactions.

The negative effects of microplastics on the normal growth of aquatic organisms have been well studied, but relatively little is known about their potential adverse effects on the function and stability of aquatic ecosystems. We investigated here the effects of polyethylene (PE) microplastics on several aspects of plankton ecosystems, including Daphnia magna behavior, the grazing rate of D. magna on Chlorella vulgaris cells, trophic-cascade effects in the C.

ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.

Recent studies have shown that the phosphorylation and dephosphorylation of ULK1 and ATG13 are related to autophagy activity. Although ATG16L1 is absolutely required for autophagy induction by affecting the formation of autophagosomes, the post-translational modification of ATG16L1 remains elusive. Here, we explored the regulatory mechanism and role of ATG16L1 phosphorylation for autophagy induction in cardiomyocytes.