Anthocyanin metabolites and related regulatory genes analysis in leaves of Acer Pseudosieboldianum mutant during different periods of color change.

Background: Acer pseudosieboldianum (Pax) Komarov, is a colorful leaf species belonging to the family Aceraceae, mainly distributed in Northeast China, Russia, and northern Korea. The leaves of Acer pseudosieboldianum are green in spring and summer, and turning red in autumn, which is of high ornamental value. In previous study, a mutant maple was selected with alternating red-green leaf color in spring and summer.

Heme oxygenase-1: potential therapeutic targets for periodontitis.

Periodontitis is one of the most prevalent inflammatory disease worldwide, which affects 11% of the global population and is a major cause of tooth loss. Recently, oxidative stress (OS) has been found to be the pivital pathophysiological mechanism of periodontitis, and overactivated OS will lead to inflammation, apoptosis, pyroptosis and alveolar bone resorption. Interestingly, heme oxygenase-1 (HO-1), a rate-limiting enzyme in heme degradation, can exert antioxidant activites through its products-carbon monoxide (CO), Fe, biliverdin and bilirubin in the inflammatory microenvironment, thus exhibiting anti-inflammatory, anti-apoptotic, anti-pyroptosis and bone homeostasis-regulating properties.

Relationship between GTP binding protein RAB10, toll-like receptor 4, and nuclear factor kappa-B and prognosis in patients with breast cancer.

The objective of this study was to investigate the correlation between Rab10 (GTP binding protein RAB10), TLR4 (Toll-like receptor 4), and NF-κB (nuclear factor kappa-B) levels and therapeutic effects in peripheral blood of patients with breast cancer after surgery. The study included 160 patients with stage I-III breast cancer who underwent surgical treatment at our hospital's Department of Breast Surgery and Oncology between January 2021 and June 2021. ELISA was used to assess Rab10, TLR4, and NF-κB levels in peripheral blood.

Characterization of the complete mitogenome of Tiarella polyphylla, commonly known as Asian foamflower: insights into the multi-chromosomes structure and DNA transfers.

Background: Tiarella polyphylla D. Don has been traditionally used to cure asthma and skin eruptions. However, the sequence and the structure of the mitogenome of T.

Control ultrafiltration membrane fouling in Chlorella-laden water treatment by integrated heat-activated peroxydisulfate pre-oxidation and coagulation treatment.

The membrane fouling induced by algal extracellular organic matter (EOM) remain a bottleneck in restricting ultrafiltration (UF) application during harmful algal-water treatment. In current study, the application of heat-activated peroxydisulfate (PMS) and coagulation (Aluminum chlorohydrate, PACI) on membrane fouling behavior during Chlorella-laden water treatment was investigated. The membrane fouling mechanism was analyzed using the extended Derjaguin-Landau-Verwey-Over-beek (XDLVO) theory.

Multi-omics reveal toxicity mechanisms underpinning nanoplastic in redclaw crayfish (Cherax quadricarinatus).

We investigated the effects of different nanoplastic (NP, size = 100 nm) concentrations on red crayfish (Cherax quadricarinatus) and examined toxicity mechanisms. We established four concentration groups (control (CK): 0 μg/L; Low: 100 μg/L; Medium: 500 μg/L; and High: 1000 μg/L) and analyzed toxicity effects in C. quadricarinatus hepatopancreas using histopathological, transcriptomic, metabolomic, and fluorescence methods.

Effects of Substituting and as Feed on Growth, Flesh Quality and Intestinal Microbiota of Red Swamp Crayfish ().

This study aimed to evaluate the impact of substituting a portion of feed with (TM) and (EN) on crayfish culture. A total of 270 crayfish (5.1 ± 0.

Effects of four types of natural bait on water quality, feeding, growth, and antioxidant enzyme activity of in a recirculating aquaculture system.

Monopterus albus is one of China's renowned and superior aquaculture species, with its seedlings mainly sourced from wild capture. One of the bottlenecks in aquaculture is the high mortality rate and low feeding initiation rate from stocking wild fry to the initiation of feeding. In production, trash fish is commonly used to wean juveniles onto feeding.

Comparative studies on the intestinal health of wild and cultured ricefield eel ().

Fish intestinal health under intensive aquaculture mode plays an important role in growth, development, and immune function. The present study was aimed to systematically investigate the differences of intestinal health between wild and cultured by biochemical parameters, histomorphology, and molecular biology. A total of 15 healthy per group, with an average body weight of 45 g, were sampled to analyze intestinal health parameters.

Effects of dietary melatonin supplementation on growth performance and intestinal health of rice field eel (Monopterus albus).

The objective was to assess the impact of melatonin supplementation on the growth performance and intestinal health of rice field eel, Monopterus albus. Three hundred and sixty fish (28.46 ± 0.

Effects on growth performance and immunity of after high temperature stress.

To investigate the impact of the effect of high temperature stimulation on larvae after a certain period of time, five experimental groups were established at different temperatures. Then, the under high temperature stress was fed at 30°C for 70 days. After that, the growth index of the was counted and analyzed.

Gradual effects of gradient concentrations of perfluorooctane sulfonate on the antioxidant ability and gut microbiota of red claw crayfish (Cherax quadricarinatus).

Perfluorooctane sulfonate (PFOS) is a typical persistent organic pollutant that is characterized by environmental persistence, bioaccumulation, and toxicity. In this study, we investigated the gut microbial response of the red claw crayfish Cherax quadricarinatus after 28 days of exposure to 0 ng/L, 1 ng/L, 10 μg/L, or 10 mg/L of PFOS as a stressor. We measured oxidative stress-related enzyme activities and expression of molecules related to detoxification mechanisms to evaluate the toxic effects of PFOS.

Potential nervous threat of nanoplastics to Monopterus albus: Implications from a metabolomics study.

Nanoplastics, as a new class of environmental pollutants, have been frequently detected in environmental media and organisms. Monopterus albus (M. albus) is an important economic aquatic product with a high dietary consumption.

Geometrically Constrained Organoboron Species as Lewis Superacids and Organic Superbases.

This report unveils an advancement in the formation of a Lewis superacid (LSA) and an organic superbase by the geometrical deformation of an organoboron species towards a T-shaped geometry. The boron dication [2] supported by an amido diphosphine pincer ligand features both a large fluoride ion affinity (FIA>SbF ) and hydride ion affinity (HIA>B(C F ) ), which qualifies it as both a hard and soft LSA. The unusual Lewis acidic properties of [2] are further showcased by its ability to abstract hydride and fluoride from Et SiH and AgSbF respectively, and effectively catalyze the hydrodefluorination, defluorination/arylation, as well as reduction of carbonyl compounds.

Polystyrene nanospheres-induced hepatotoxicity in swamp eel (Monopterus albus): From biochemical, pathological and transcriptomic perspectives.

As ubiquitous emerging pollutants, microplastics (MPs) in aquatic environments have aroused critical global concerns. Despite the occurrence and characteristics of MPs in freshwater agroecosystems well-described by our previous study, their ecotoxicological implications in Monopterus albus remains unfathomed. Herein, we dissected toxic effects and mechanisms of PS-NPs exposure against M.

Dietary polystyrene nanoplastics exposure alters hepatic glycolipid metabolism, triggering inflammatory responses and apoptosis in Monopterus albus.

Microplastics and nanoplastics (MPs and NPs) are abundant, persistent, and widespread environmental pollutants that are of increasing concern as they pose a serious threat to ecosystems and aquatic species. Identifying the ecological effects of NPs pollution requires understanding the effects of changing nanoplastics concentrations in aquatic organisms. Monopterus albus were orally fed three different concentrations of 100 nm polystyrene nanoplastics (PS-NPs): 0.

The relationship between the interactive behavior of industry-university-research subjects and the cooperative innovation performance: The mediating role of knowledge absorptive capacity.

Introduction: Industry-university-research cooperation innovation, which is often characterized by resource complementarity and the sharing technology, has become one of the most preferred innovation cooperation methods for enterprises. However, various problems still occur in the process of industry-university-research cooperations, such as poor innovation performance and difficulty in sustaining cooperation. Existing studies mostly focus on the macroscopic perspectives of geographic location, cooperation scale, concentration, and diversification of industry-university-research cooperation subjects, and fail to explore the microscopic behavioral mechanisms.

Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancer.

Despite neoadjuvant/conversion chemotherapy, the prognosis of cT4a/bN+ gastric cancer is poor. Immune checkpoint inhibitors (ICIs) and antiangiogenic agents have shown activity in late-stage gastric cancer, but their efficacy in the neoadjuvant/conversion setting is unclear. In this single-armed, phase II, exploratory trial (NCT03878472), we evaluate the efficacy of a combination of ICI (camrelizumab), antiangiogenesis (apatinib), and chemotherapy (S-1 ± oxaliplatin) for neoadjuvant/conversion treatment of cT4a/bN+ gastric cancer.

Impact of shift work on surgical outcomes at different times in patients with acute type A aortic dissection: A retrospective cohort study.

Background: To investigate the effect of shift work on surgical outcomes at different times in patients with acute type A aortic dissection (ATAAD).

Materials And Methods: Patients with ATAAD who underwent total arch replacement at Qilu Hospital of Shandong University from January 2015 to March 2022 were retrospectively analyzed. All patients were managed according to the green channel emergency management strategy, and a professional cardiac team was arranged during off-hours.

Investigation of membrane fouling and mechanism induced by extracellular organic matter during long-term exposure to pharmaceuticals and personal care products.

This study investigated ultrafiltration membrane fouling by extracellular organic matter (EOM) and the mechanism operating during long-term exposure to pharmaceuticals and personal care products. The results indicated that carbamazepine and diclofenac in algal-laden water altered the filtration flux and membrane fouling by EOM. Exposure to low-concentration carbamazepine (0.

Asian Swamp eel Population Structure and Genetic Diversity in China.

The Asian swamp eel () is one of the most widely distributed freshwater fish in China. In this study, we identified the single nucleotide polymorphisms (SNPs) of from 19 wild populations in China using restriction-site associated DNA sequencing (RAD-seq), and used SNP markers to investigate the swamp eel the genetic diversity and population genetic structure. A total of 8941794 SNPs were identified.

Effects of reduced salinity caused by reclamation on population and physiological characteristics of the sesarmid crab Chiromantes dehaani.

Reduced salinity is a major factor that causes macrobenthic degradation in reclaimed wetlands. We investigated populations of the sesarmid crab Chiromantes dehaani in reclaimed and natural wetlands. Then, in the laboratory, we exposed male and female crabs to four salinity levels (0, 6, 12 and 18) for 96 h to analyse the effects of reduced salinity on osmoregulatory enzyme activities in the posterior gills and digestive and immune enzyme activities in the hepatopancreas of C.

Diatomite Dynamic Membrane Fouling Behaviour during Dewatering of in Aquaculture Wastewater.

Combined microalgal and membrane filtration could effectively treat aquaculture wastewater; however, the membrane fouling induced by extracellular organic matter (EOM) during the dewatering process is an issue. This study investigated diatomite dynamic membrane (DDM) fouling behaviour during the dewatering of under the influence of copper ions. The results indicate that copper ion heavy metals in aquaculture wastewater significantly affected purification and algae dewatering by DDM.