Refined Industrial Tannins via Sequential Fractionation: Exploiting Well-Defined Molecular Structures for Controlled Performance in Pickering Emulsions Costabilized with Chitin Nanofibrils.

Tannins from (black wattle) are one of the few industrially available sources of nonlignin polyphenols. The intrinsic chemical heterogeneity and high dispersity of industrial tannins complicate their use in applications where the reactivity or colloidal interactions need to be precisely controlled. Here, we employ a solubility-centered sequential fractionation to obtain homogeneous tannin fractions with a dispersity index lower than 2.

Biodegradable exosome-engineered hydrogels for the prevention of peritoneal adhesions via anti-oxidation and anti-inflammation.

Peritoneal adhesions (PA) are a common and severe complication after abdominal surgery, impacting millions of patients worldwide. The use of anti-adhesion materials as physical barriers is an effective strategy to prevent postoperative adhesions. However, the local inflammatory microenvironment exerts a significant impact on the efficacy of anti-adhesion therapies.

-Derived Extracellular Vesicles Prevent Hepatocellular Carcinoma by Modulating the TGF-β1/Smad Signaling in Mice.

Background: The involvement of gut microbiota in carcinogenesis has gradually been highlighted in past decades. Bacteria could play its role by the secretion of extracellular vesicles (EVs); however, interrelationship between bacterial EVs and hepatocellular carcinoma (HCC) development has not been investigated much.

Methods: Diethylnitrosamine (DEN) was utilized to produce HCC model in mice, of which fecal was collected for detecting () with real-time polymerase chain reaction (PCR).

An injectable exosome-loaded hyaluronic acid-polylysine hydrogel for cardiac repair via modulating oxidative stress and the inflammatory microenvironment.

Myocardial infarction (MI) is a serious cardiovascular disease with complex complications and high lethality. Currently, exosome (Exo) therapy has emerged as a promising treatment of ischemic MI due to its antioxidant, anti-inflammatory, and vascular abilities. However, traditional Exo delivery lacks spatiotemporal precision and targeting of microenvironment modulation, making it difficult to localize the lesion site for sustained effects.

Chronological-Programmed Black Phosphorus Hydrogel for Responsive Modulation of the Pathological Microenvironment in Myocardial Infarction.

Electroactive hydrogels have garnered extensive interest as a promising approach to myocardial tissue engineering. However, the challenges of spatiotemporal-specific modulation of individual pathological processes and achieving nontoxic bioresorption still remain. Herein, inspired by the entire postinfarct pathological processes, an injectable conductive bioresorbable black phosphorus nanosheets (BPNSs)-loaded hydrogel (BHGD) was developed reactive oxide species (ROS)-sensitive disulfide-bridge and photomediated cross-linking reaction.

Climate change impacts on wastewater infrastructure: A systematic review and typological adaptation strategy.

Wastewater infrastructures play an indispensable role in society's functioning, human production activities, and sanitation safety. However, climate change has posed a serious threat to wastewater infrastructures. To date, a comprehensive summary with rigorous evidence evaluation for the impact of climate change on wastewater infrastructure is lacking.

Preoperative Risk Factor Analysis and Dynamic Online Nomogram Development for Early Infections Following Primary Hip Arthroplasty in Geriatric Patients with Hip Fracture.

Background: Hip arthroplasty is in increasing demand with the aging of the world population, and early infections, such as pneumonia, surgical site infection (SSI), and urinary tract infection (UTI), are uncommon but fatal complications following hip arthroplasty. This study aimed to identify preoperative risk factors independently associated with early infections following primary arthroplasty in geriatric hip fracture patients, and to develop a prediction nomogram.

Methods: Univariate and multivariate logistical analyses were performed to identify the independent risk factors for early infections, which were combined and transformed into a nomogram model.

The efficacy of Azotobacter chroococcum in altering maize plant-defense responses to armyworm at elevated CO concentration.

Elevated atmospheric carbon dioxide (eCO) concentrations can alter the carbon:nitrogen ratio and palatability of host plants for herbivorous insects, but rhizobacteria likely mitigate the alteration and influence physiological adaptation of insects. In this study, we conducted transcriptomic analysis of maize (Zea mays) response to Azotobacter chroococcum (AC) inoculation under eCO conditions in contrast to ambient CO (aCO), and studied the effects of plant-defense change of maize under eCO on the oriental armyworm, Mythimna separata. Results showed that there were 16, 14, 16 and 135 differentially expressed genes that were associated with plant-defense response in maize leaves between aCO-CK and aCO-AC, eCO-CK and eCO-AC, aCO-CK and eCO-CK, aCO-AC and eCO-AC, respectively.

Two-step pyrolysis biochar derived from agro-waste for antibiotics removal: Mechanisms and stability.

This study used acetone washing biochar (BCA) and nitric-acid washing biochar (BCN) derived from bagasse to remove sulfamethoxazole (SMX) and tetracycline (TC) in water. Higher specific surface area (1119.53 m g) and graphitization degree can significantly improve decontamination efficacy, of which BCN has the highest SMX and TC sorption capacities (274.

Temporal and spatial variations of soil C, N contents and C:N stoichiometry in the major grain-producing region of the North China Plain.

Soil C, N contents and C:N stoichiometry are important indicators of soil quality, the variation characteristics of which have great significance for soil carbon-nitrogen cycle and sustainable utilization. Based on 597 observations along with soil profiles of 0-20cm depth in the 1980s and the 2010s, the temporal and spatial variations of soil C, N contents and C:N stoichiometry in the major grain-producing region of the North China Plain were illustrated. Results showed that there were significant changes in soil C, N contents over time, with increasing rates of 60.

Antagonistic effects of multi-walled carbon nanotubes and BDE-47 in zebrafish (Danio rerio): Oxidative stress, apoptosis and DNA damage.

In natural environments, organisms are often exposed to several environmental pollutants at any one time, and the potential effects of such co-exposures on human and environmental health are of considerable concern. It is thought that multi-walled carbon nanotubes (MWCNTs) may interact with other pollutants in aquatic systems and induce considerably different effects compared with exposure to a single contaminant. The objective of this study was to evaluate the potential acute combined effects of mixtures of MWCNTs and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on embryonic development stages, oxidative stress, apoptosis and DNA damage in developing zebrafish (Danio rerio).

Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring.

Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a re-emerging environmental contaminant used as a suitable substitute for brominated flame retardants. The objective of this study was to evaluate the effects of TDCIPP on thyroid disruption and growth inhibition in zebrafish (Danio rerio) offspring after chronic parental exposure, and to examine the possible molecular mechanisms involved. When adult zebrafish (4 months old) were exposed to 5.