Surgical Efficacy and Prognosis of 54 Cases of Spinal Metastases from Breast Cancer.

Objective: To analyze the efficacy and complications of spinal metastasis surgery for breast cancer; to understand the survival and the influencing factors; and to verify the predictive ability of the currently used spinal metastasis cancer survival prediction scoring system on 1 year postoperative survival.

Methods: A retrospective study was conducted of 54 patients with spinal metastases from breast cancer who underwent open surgery after multidisciplinary consultation in our hospital from January 2017 to October 2020. Patient demographic-related variables, breast cancer-related variables, spinal disorder-related variables, and treatment-related variables were collected.

Efficacy and safety of apatinib in advanced sarcoma: an open-label, nonrandomized, single-center study of 45 patients.

Sarcoma is a rare tumor with more than 50 histologic subtypes. Patients with advanced sarcoma have a poor prognosis. The aim of this study was to evaluate the efficacy and safety of apatinib, an oral vascular endothelial growth factor receptor-2 inhibitor, as salvage treatment for advanced bone and soft tissue sarcomas.

Finite element analysis of a bone healing model: 1-year follow-up after internal fixation surgery for femoral fracture.

Finite element analysis was used to compare preoperative and postoperative stress distribution of a bone healing model of femur fracture, to identify whether broken ends of fractured bone would break or not after fixation dislodgement one year after intramedullary nailing. Method s: Using fast, personalized imaging, bone healing models of femur fracture were constructed based on data from multi-slice spiral computed tomography using Mimics, Geomagic Studio, and Abaqus software packages. The intramedullary pin was removed by Boolean operations before fixation was dislodged.

Use of gluteus maximus adipomuscular sliding flaps in the reconstruction of sacral defects after tumor resection.

Background: While performing sacrectomy from a posterior approach enables the en bloc resection of sacral tumors, it can result in deep posterior peritoneal defects and postoperative complications. We investigated whether defect reconstruction with gluteus maximus (GLM) adipomuscular sliding flaps would improve patient outcomes.

Methods: Between February 2007 and February 2012, 48 sacrectomies were performed at He Nan Cancer Hospital, Zhengzhou City, China.

Epiphysis preserving operations for the treatment of lower limb malignant bone tumors.

Purpose: To assess two epiphyseal sparing procedures for the treatment of lower limb malignant bone tumors.

Methods: Between January 2007 and January 2011, 15 patients, seven males and eight females with a mean age of 11.75 years (range, 7-24), underwent epiphysis preservation operations.

Open vertebroplasty in the treatment of spinal metastatic disease.

Background: Metastatic spine tumors can cause vertebral body (VB) osteolysis, microfractures, and/or compression fractures, and requires restabilization of the VB. Curative or curettage surgery, such as vertebrectomy and reconstruction, is currently the main method of treatment. In certain situations however, such as a patient's poor condition, multi-level involvement, or a limited life expiration, major surgery is not recommended.

Bone regeneration using an injectable calcium phosphate/autologous iliac crest bone composites for segmental ulnar defects in rabbits.

Background: Treatment of segmental bone loss remains a challenge in skeletal repair. A major therapeutic goal is the development of implantable materials that will promote bone regeneration.

Objective: We evaluate bone regeneration in grafts containing different concentrations autologous iliac crest bone (ACB) particles, carried in a new injectable calcium phosphate cement (CPC), in ulnar bone defects in rabbits.

An injectable cement: synthesis, physical properties and scaffold for bone repair.

Unlabelled: Micro-invasive bone grafting is to deliver bone graft materials to the desired site through local puncturation and injection. It has many advantages such as little injury, simple procedures and high efficiency of osteogenesis. Limited sources of graft materials and complicated procedures are the main factors affecting the development of the technique.