Publications by authors named "Weitao Li"

Methyl orange (MO) is an organic synthetic dye widely used in laboratory and industrial applications. In laboratory settings, it serves as an acid-base indicator due to its distinct color change in both acidic and alkaline environments. Industrially, it is primarily utilized in the textile industry for its ultraviolet (UV) absorption properties.

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The increasing threat of biological invasion poses significant challenges to global ecosystems, necessitating urgent management measures. This study investigated the potential of biochar derived from invasive plant , produced through anaerobic digestion, as a tool for mitigating the soil legacy effects of this species and restoring the plant community. Soil samples were collected from artificially constructed plots of invasive plant communities and were subjected to treatments with different levels of fungicide and biochar addition.

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Purpose: To evaluate the effects of axial length and slot-to-slot distance of double-slot microwave antenna (DSMA) with frequency of 433 MHz on the size and shape of ablation zones created under different input microwave powers.

Materials And Methods: The design of double slot microwave antennas (DSMAs) with axial lengths (70 mm, 30 mm) and slot-to-slot distance (49 mm, 10 mm) were optimized by numerical simulation and ex vivo liver experiments. Finite-element method simulations and forty ablations of swine liver were employed to obtain the temperature distributions within liver tissue using DSMAs at the 433 MHz operating frequency in a range of heating powers (20, 30, 40 and 50W) for 600 s.

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Hydrogen peroxide (HO) is a ubiquitous signal regulating many biological processes, including innate immunity, in all eukaryotes. However, it remains largely unknown that how transcription factors directly sense HO in eukaryotes. Here, we report that rice basic/helix-loop-helix transcription factor bHLH25 directly senses HO to confer resistance to multiple diseases caused by fungi or bacteria.

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Low-frequency non-syndromic hearing loss (LFNSHL) is a rare auditory disorder affecting frequencies ≤ 2000 Hz. To elucidate its genetic basis, we conducted whole-exome sequencing on nine Chinese families (31 affected individuals) with LFNSHL. Four heterozygous pathogenic variants, including two novel variants, were identified in common LFNSHL-related genes (WFS1, DIAPH1) and less common genes (TNC, EYA4), achieving a 44% genetic diagnosis rate.

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Research on the waterlogging tolerance mechanisms of helps us to further understand these mechanisms in the root system and enhance its root bark and oil yields in southern China. In this study, root morphological identification, the statistics of nine physiological and biochemical indicators, and a comparative transcriptome analysis were used to investigate the waterlogging tolerance mechanism in this plant. As flooding continued, the roots' vigor dramatically declined from 6 to 168 h of waterlogging, the root number was extremely reduced by up to 95%, and the number of roots was not restored after 96 h of recovery.

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Plants mount induced resistance and adult-plant resistance against different pathogens throughout the whole growth period. Rice production faces threats from multiple major diseases, including rice blast, sheath blight, and bacterial leaf blight. Here, we report that the miR172a-SNB-MYB30 module regulates both induced and adult-plant resistance to these three major diseases via lignification in rice.

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Studies show that movement observation (MO), movement imagery (MI), or movement execution (ME) based brain-computer interface systems are promising in promoting the rehabilitation and reorganization of damaged motor function. This study was aimed to explore and compare the motor function rehabilitation mechanism among MO, MI, and ME. 64-channel electroencephalogram and 4-channel electromyogram data were collected from 39 healthy participants (25 males, 14 females; 18-23 years old) during MO, ME, and MI.

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Article Synopsis
  • Peanuts are a vital source of vegetable oils and proteins, but understanding how their oil and protein contents are regulated is still a challenge.
  • Researchers analyzed peanut seeds from two different varieties, "YH15" (high in oil) and "KB008" (high in protein), at four developmental stages using metabolomics and transcriptome analysis.
  • They discovered 984 differential metabolites and identified key gene modules linked to the differences in oil and protein contents, providing insights for future peanut variety cultivation with improved nutritional value.
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  • The Bighead carp, a significant aquaculture species in China, faces threats from overfishing and environmental changes, leading to concerns about its genetic diversity.
  • A study using RAD-seq analyzed 14 populations of Bighead carp from the Yangtze River and Illinois River, revealing variations in genetic diversity and deficiencies in some populations.
  • The research provides important data for managing genetic resources to ensure sustainable aquaculture practices and biodiversity conservation for the species.
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The loss and gain of OsNAS3 function both positively influence plant disease resistance. Overexpression of OsNAS3 boosts blast resistance by promoting nicotianamine accumulation, thereby enhancing blast resistance. Conversely, knockout of OsNAS3 increases ethylene biosynthesis, also contributing to improved blast resistance.

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  • Inflammasomes are key in fighting infections, and the study focuses on how HSV-1, a contagious virus, uniquely interacts with the host's immune response.
  • The researchers discovered that a gene called TET3 is critical for HSV-1 infection, as it helps activate a specific inflammasome in the nucleus by binding to caspase-1.
  • Blocking TET3’s interactions can hinder the virus’s ability to spread, suggesting potential new treatments for HSV-1 infections in the future.
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  • Messenger RNA modifications are crucial for RNA biology, and this study reveals how ac4C modification influences translational reprogramming in plants during immune responses to pathogens like Magnaporthe oryzae.* -
  • Researchers found that ac4C modifies mRNA at specific locations, particularly enhancing codon stability, which plays a vital role in regulating protein synthesis during pathogen attacks.* -
  • The increased expression of the ac4C writer enzyme OsNAT10/OsACYR leads to stronger immune responses in plants, including boosting jasmonic acid production, highlighting the importance of ac4C in plant immunity.*
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The Ideal Plant Architecture 1 (IPA1) transcription factor promotes rice yield and immunity through phosphorylation at its amino acid residue Ser163 as a switch. Although phosphorylated IPA1 mimic, IPA1(S163D), directly targets the promoter of immune response gene WRKY45, it cannot activate its expression. Here, we identified a co-activator of IPA1(S163D), a RING-finger E3 ligase IPA1 interactor 7 (IPI7), which fine-tunes the transcriptional activity of IPA1 to timely promote plant immunity and simultaneously maintain growth for yield.

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Cardiac mesoderm enhancer-associated non-coding RNA (CARMN), an evolutionarily conserved long non-coding RNA (lncRNA), serves as the host gene for the miR143/145 cluster. It plays a crucial role in cardiovascular cell differentiation and the maintenance of vascular smooth muscle cell (VSMC) homeostasis, which are vital for normal physiological processes. Specifically, CARMN is associated with the pathological progression of cardiovascular diseases such as atherosclerosis, abdominal aortic aneurysm, and chronic heart failure.

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The colonization of alien plants in new habitats is typically facilitated by microorganisms present in the soil environment. However, the diversity and structure of the archaeal, bacterial, and fungal communities in the latitudinal spread of alien plants remain unclear. In this study, the rhizosphere and bulk soil of Chromolaena odorata were collected from five latitudes in Pu' er city, Yunnan Province, followed by amplicon sequencing of the soil archaeal, bacterial, and fungal communities.

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  • Immunity and flowering in rice are energy-intensive processes, and the study reveals how the E3 ligase IPI1 regulates both through distinct mechanisms.
  • IPI1 prevents the degradation of the E3 ligase APIP6 without using its own E3 ligase activity, which in turn helps in degrading APIP6's targets through the ubiquitin-proteasome system.
  • Additionally, IPI1 directly ubiquitinates OsELF3-1 and OsELF3-2, leading to their degradation and causing IPI1 knockout plants to flower early but lose resistance to rice blast disease.
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Very-long-chain fatty acids (VLCFAs) regulate biophysical properties of cell membranes to determine growth and development of eukaryotes, such as the pathogenesis of the rice blast fungus Magnaporthe oryzae. The fatty acid elongase Elo1 regulates pathogenesis of M. oryzae by modulating VLCFA biosynthesis.

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As a new type of porous crystalline composite material, MOF-COF has shown great advantages in metal separation. Herein, a CoMOF-COF was designed for highly selective separation of trace Pb ions. The designed CoMOF-COF has a high density of nitrogen-oxygen functional groups and can selectively separate metal ions.

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Surface enhanced Raman spectroscopy (SERS) is a highly sensitive analytical detection method commonly employed in biochemical and environmental analysis. Nevertheless, the rapid movement of analytes and interfering components in flow systems can impact the real-time, online detection capability of Raman spectroscopy. To address this issue, we developed an innovative approach utilizing covalent organic framework (COF), a robust porous material with excellent water stability, to coat the surface of Ag nanowire (AgNW) for synthesizing AgNW@COF hybrid.

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Elastography is a noninvasive technique for characterizing the mechanical properties of biological tissues. Conventional methods have limitations in resolution and sensitivity, hindering disease detection in clinical diagnostics. To address these issues, this study developed an optical-resolution photoacoustic microelastography (OR-PAME) system.

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This paper presents the development of a fiber-optic-based fluorescence detection system for multi-scale monitoring of drug distribution in living animals. The integrated system utilized dual laser sources at the wavelengths of 488 nm and 650 nm and three photomultiplier channels for multi-color fluorescence detection. The emission spectra of fluorescent substances were tracked using the time-resolved fluorescence spectroscopy module to continuously monitor their blood kinetics.

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Pyrethroid pesticides (PYRs) have found widespread application in agriculture for the protection of fruit and vegetable crops. Nonetheless, excessive usage or improper application may allow the residues to exceed the safe limits and pose a threat to consumer safety. Thus, there is an urgent need to develop efficient technologies for the elimination or trace detection of PYRs from vegetables.

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Auxin is an important phytohormone that regulates diverse biologic processes, including plant growth and immunity. Indole-3-acetic acid (IAA), known as one of the main forms of auxin, is able to activate plant immunity. However, it is unknown whether IAA enhances plant resistance and/or suppresses the growth of the fungal pathogen .

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Pelvic girdle pain (PGP) is a common problem during pregnancy and postpartum and negatively affects women's well-being. Yet it is not well known in China. This study assessed PGP's intensity, location, and quality and the status of daily activities on postpartum women with pain, and explored the relationship between pain and the prevalence of depressive symptoms.

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