Pentraxin3 exacerbates acute pancreatitis injury by inhibiting oxidative phosphorylation pathway.

Local pancreatic necrosis and systemic inflammatory response caused by acute pancreatitis (AP) are closely related to the disease prognosis and severity. This study aimed to explore whether pentraxin 3 (PTX3) regulates AP pancreatic necrosis and reveals the underlying mechanism. By using AP time gradient transcriptomics, proteomics and liquid phase chip analysis, we found a close association between PTX3 and AP.

[Thyroid nodules with calcification and thyroid carcinoma].

Objective: To investigate the significance of thyroid calcification for diagnosis of thyroid carcinoma.

Methods: Retrospective analysis of 817 thyroid nodules' pre-operative ultrasonic and postoperative pathologic results.

Results: Total ultrasonic thyroid calcification ratio was 18.

[Single-dose ceftriaxone versus multiple-dose cefuroxime for prophylaxis of surgical site infection].

Objective: To compare the effects and pharmacoeconomics of single-dose of ceftriaxone versus 3-day cefuroxime prophylaxis in patients undergoing gastric or colorectal resection.

Methods: Three hundred and five consecutive patients with gastric or colorectal cancer from 5 medical centers were randomly divided into ceftriaxone group (n = 153, receiving intravenously 1 g ceftriaxone 0.5 - 1 h prior to operation only) and cefuroxime group (n = 152, receiving 0.

[Non-functional islet-cell tumor: analysis of 237 cases].

Objective: To summarize the clinical aspects of nonfunctional islet-cell tumor (NIT) reported in Chinese periodicals.

Methods: Articles in Chinese on NIT were screened from the Chinese Bio-Medical Database (1981.1 - 1999.