Comparison of classical dermatoscopy and acrylic globe magnifier dermatoscopy.

Dermatoscopic asymmetry of melanocytic skin lesion is pivotal in most algorithms assessing the probability of melanoma. Larger lesions cannot be assessed by dermatoscopy and the Dermaphot in a single field of vision, but this can be performed using the acrylic globe magnifier. We examined the diagnostic accuracy of the acrylic globe magnifier and compared it with classical dermatoscopy.

Phytophotodermatitis in 19 children admitted to hospital and their differential diagnoses: Child abuse and herpes simplex virus infection.

Background: Phytophotodermatitis is a non-immunologic cutaneous reaction that can be provoked after contact with plants containing psoralens followed by sun exposure.

Objectives: The purpose of this study is to describe the clinical features of phytophotodermatitis and its differential diagnoses, especially child abuse and herpes virus infection.

Methods: Nineteen children seen in two county hospitals are described.

[Acute necrosis of the skin--a possible result from the bite of a Hobo-spider].

A 63-year-old male presented with painful erythema and bullae on his left knee. When working on his boat he suddenly felt a burning sensation followed by numbness of the area. The sensation wore off, but was followed by painful erythema and necrosis.

Poppyfield bleeding: a new dermatoscopic sign and its histopathological background.

Dermatoscopy increases the accuracy of diagnosis of melanoma. An atypical vascular pattern may be an indicator of cutaneous malignant melanoma (CMM). During dermatoscopy of certain CMMs numerous ruby droplets of blood appear when the dermatoscope is pressed firmly against the lesion.

[Dynamic dermoscopy].

Dermoscopy of early-stage melanoma can be challenging, and repeated examination at three-month intervals may disclose subtle changes. In patients with atypical nevus syndrome or more than 50 nevi, repetitive excision of benign lesions does not guarantee that melanomas will be identified at an early stage and exposes patients to potentially disfiguring surgery. We present the case of a high-risk patient where repeated dermoscopy of an in situ melanoma showed that part of the pigment network had coarsened, even though the lesion had not changed macroscopically.

[Imiquimod treatment of lentigo maligna to dermoscopic and histologic clearance].

Imiquimod is an immune system-modifying drug that switches the immune system to a Th1 response, enabling it to defeat virus-infected and neoplastic cells. We report on a 94-year-old woman with a large lentigo maligna (LM) on her cheek whom we treated with imiquimod 5% cream. Dermoscopy was used to identify the most suspect areas of the lesion for biopsy and in follow-up.

Neutrophil dermatosis of the dorsal hands.

Neutrophil dermatosis of the dorsal hands (NDDH) is a recently described skin manifestation regarded as a subset of acute febrile neutrophilic dermatotis (Sweet syndrome). We describe 5 cases with pustular and ulcerative plaques and/or bullae and vesicles of the dorsal hands. Three of the patients also had skin changes at sides other than the hands.

Incidence, clinical presentation and treatment of neurosyphilis in Denmark 1980-1997.

Neurosyphilis is now a rare disease in the developed countries. In Denmark 92 cases of neurosyphilis were identified in the period 1980-1997. We obtained the hospital records for 77 of these patients and studied the clinical presentation, treatment and result of the treatment.

Treatment of Bowen's disease of the penis with imiquimod 5% cream.

We present a case of persistent and progressive Bowen's disease (squamous cell carcinoma in situ) of the penis, in an otherwise healthy 56-year-old man. Treatment with imiquimod 5% cream was effective when applied once a day for 3 consecutive days followed by 4 days without treatment, over a period of 5 weeks.

[The shadow rule and appropriate sun behavior].

Introduction: Sun lotions have not been effective in preventing the alarming increase in the incidence of melanoma, possibly, because of incorrect use, lack of protection from UVA and increased exposure times caused by reduced penetration of erythemogenic UVB. Seeking shade prevents deleterious effects from the sun's ultraviolet rays.

Material And Methods: We examined the association between UV intensity and the ratio of shadow length to object height.

[Institutional scabies].

We describe an outbreak of scabies affecting 13 patients and staff members in a geriatric ward. The difficulties of diagnosis and treatment are discussed, and it is suggested that the local hygiene unit should be involved immediately if institutional scabies is suspected.

[Scabies].

The aim of this review is to draw attention to the fact that scabies still causes clinical problems and gives rise to epidemics in hospitals and institutions. We describe the clinical aspects of ordinary and crusted scabies and newer diagnostic methods, such as epiluminescence microscopy and PCR. The current treatment of scabies in Denmark is mentioned, and the importance of simultaneous preventative treatment of household contacts and hygienic measures in the surroundings is emphasised.

[Airborne contact allergy provoked by kathon in water-based plastic paint].

We describe two cases of airborne contact allergy to plastic paint containing Kathon. Two women with known kathon allergy, aged 33 and 50 years, developed severe dermatitis and systemic reactions after painting their homes with water-based plastic paint with Kathon as preservative. Both required treatment with systemic steroids.

Melanocytic proliferations associated with lichen sclerosus.

Objectives: To describe the clinicopathologic features of melanocytic proliferations associated with lichen sclerosus (LS) and to compare these findings with those in controls.

Design: Cohort study.

Setting: Academic and private practice dermatology and dermatopathology services.