Efficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy.

Background: The best tool for the management of pain associated with distal symmetric peripheral neuropathy (DSPN) is a matter of debate. Therefore, the study aimed to explore whether ultrasound-guided pulsed radiofrequency (PRF) therapy of the stellate ganglion (SG) in type 2 diabetes mellitus (T2DM) patients with painful DSPN could decrease pain severity and the need for analgesics.

Methods: Fifty-six T2DM patients with refractory painful DSPN were enrolled in this study, who then received bilateral ultrasound-guided PRF therapy of SG.

[Fat and fatty acid content in freshwater and saltwater fish in 4 provinces].

Objective: To explore the differences in fat and fatty acids content between freshwater and saltwater fish.

Methods: The fat and fatty acids content in 83 fish meat samples from four regions(Hainan, Jiangsu, Fujian, and Guangxi) were detected by national standard method. Mann-Whitney U tests and t-tests were used to compare the differences in fat and major fatty acid content between freshwater and saltwater fish.

[Differences and correlations in phenolic acid content in the pulp of various categories of fruits in Shenzhen].

Objective: To detect phenolic acid compounds in various fruits and explore the differences in phenolic acids among different types of fruits.

Methods: The collected 75 types of fruits were classified into 6 categories: citrus、melon、drupe、berry、tropical fruit and pome fruits. The phenolic acid compounds were detected by high performance liquid chromatography-mass spectrometry.

Correlations Between the Bacterial and Fungal Flora and Amino Acid Composition of the Zhuangzu Acid Congee Produced Around the Zuojiang River Basin, Guangxi.

In this study, the bacterial, fungal, and amino acid compositions of the Zhuangzu acid congee (ZAC) along the Zuojiang River of Guangxi were analyzed. A total of 14 samples of ZAC were collected in four regions: Fusui (F), Ningming (N), Xiashi (X), and Suxu (S). The predominant bacterial phyla of the four groups were Firmicutes and Proteobacteria.

Enhancement of far-infrared laser damage threshold in Ge-As-Se glass fiber.

The application of As-Se chalcogenide glasses in high-power laser delivery is hindered by their low damage threshold due to their weak chemical bonds. To solve this, we introduced germanium elements into the As-Se glasses and optimized the composition to raise the glass transition temperature (T) and enhance the laser damage threshold (LDT). From the correlation among various parameters including T, LDT, and fiber loss, we concluded an optimized composition of GeAsSe/GeAsSe glass.

DMEDH: diffusion model-boosted multiplane extrapolation for digital holographic reconstruction.

Digital holography can reconstruct the amplitude and phase information of the target light field. However, the reconstruction quality is largely limited by the size of the hologram. Multi-plane holograms can impose constraints for reconstruction, yet the quality of the reconstructed images continues to be restricted owing to the deficiency of effective prior information constraints.

[Determination of 13 kinds of free and bound phenolic acids in fruits by high-performance liquid chromatography-mass spectrometry].

Objective: To establish a high-performance liquid chromatography-mass spectrometry(HPLC-MS/MS) method for detecting 13 kind of free and bound phenolic acids(chlorogenic acid, protocatechuic acid, ferulic acid, p-coumaric acid, gallic acid, gentisic acid, vanillic acid, caffeic acid, syringic acid, sinapic acid, rosmarinic acid, salicylic acid, p-hydroxybenzoic acid) in fruits, and optimize the pre-treatment conditions to meet the detection requirements for phenolic acid content in various types of fruits.

Methods: Free phenolic acids in fruits were extracted using methanol through ultrasonic extraction. Conjugated phenolic acids in the centrifuged residue were released by alkaline hydrolysis and extracted with ethyl acetate.

Cross-layer importance evaluation for neural network pruning.

Filter pruning has achieved remarkable success in reducing memory consumption and speeding up inference for convolutional neural networks (CNNs). Some prior works, such as heuristic methods, attempted to search for suitable sparse structures during the pruning process, which may be expensive and time-consuming. In this paper, an efficient cross-layer importance evaluation (CIE) method is proposed to automatically calculate proportional relationships among convolutional layers.

Metabolite profiling of camel milk and the fermentation bacteria agent TR1 fermented two types of sour camel milk using LC-MS in relation to their probiotic potentials.

Camel milk is a nutrient-rich diet and fermentation affects its nutritional value and probiotic function. In this study, sour camel milk and oat jujube sour camel milk were prepared using fermentation bacteria agent TR1, and the metabolites of camel milk, sour camel milk and oat jujube sour camel milk were detected using a non-targeted metabolomics approach using liquid chromatography-mass spectrometry (LC-MS).The results showed that the partial least squares discriminant analysis (PLS-DA) with 100 % accuracy and good predictive power detected 343 components in positive ion mode and 220 components in negative ion mode.

[Study on the total flavonoid content and antioxidant activity of Morus nigra Linn. from different origins in Xinjiang].

Objective: Optimization of the extraction process of total flavonoids from Morus nigra Linn. based on response surface design, to compare the differences in total flavonoid content of Morus nigra Linn. from different origins in Xinjiang and its relationship with antioxidant activity.

A Combined UWB/IMU Localization Method with Improved CKF.

Aiming at the problem that ultra-wide band (UWB) cannot be accurately localized in environments with large noise variations and unknown statistical properties, a combinatorial localization method based on improved cubature (CKF) is proposed. First, in order to overcome the problem of inaccurate local approximation or even the inability to converge due to the initial value not being set near the optimal solution in the process of solving the UWB position by the least-squares method, the Levenberg-Marquardt algorithm (L-M) is adopted to optimally solve the UWB position. Secondly, because UWB and IMU information are centrally fused, an adaptive factor is introduced to update the measurement noise covariance matrix in real time to update the observation noise, and the fading factor is added to suppress the filtering divergence to achieve an improvement for the traditional CKF algorithm.

[Analysis on vitamin B_1 and vitamin B_2 proficiency testing assessment in China disease control and prevention system].

Objective: To evaluate the detection ability of vitamin B_1 and vitamin B_(2 )in rice flour in the laboratories of disease control and prevention system, by conducting the proficiency testing(PT)activity.

Methods: Before the vitamin B_1 and vitamin B_2 quality control samples were distributed to the laboratories of disease control and prevention system, the uniformity and stability of samples were analyzed by one-way ANOVO respectively. High performance liquid chromatography(HPLC) method was required to determine vitamin B_1(GB 5009.

Formate Might Be a Novel Potential Serum Metabolic Biomarker for Type 2 Diabetic Peripheral Neuropathy.

Background: As one of the most frequent complications of type 2 diabetes mellitus (T2DM), diabetic peripheral neuropathy (DPN) shows a profound impact on 50% of patients with symptoms of neuropathic pain, numbness and other paresthesia. No valid serum biomarkers for the prediction of DPN have been identified in the clinic so far. This study is to investigate the potential serum biomarkers for DPN firstly based on H-Nuclear Magnetic Resonance (H-NMR)-based metabolomics technique.

Development of a sensitive simultaneous analytical method for 26 targeted mycotoxins in coix seed and Monte Carlo simulation-based exposure risk assessment for local population.

Coix seed, a versatile agricultural product, is known for its nutritional and functional components. However, the common contamination with mycotoxins represents a potential risk for human health. A sensitive analytical method was developed and validated to simultaneously determine 26 mycotoxins, including regulated and emerging, using stable-isotope-dilution-assay and LC-MS/MS.

Analysis of metabolites of bactrain camel milk in Alxa of China before and after fermentation with fermenting agent TR1 based on untargeted LC-MS/MS based metabolomics.

Camel milk produces many beneficial functional compounds and affects body health through metabolism. The differential metabolites of bactrain camel milk in Alxa before and after fermentation were identified by liquid chromatography-tandem mass spectrometry based metabolomics (LC-MS/MS). The differential metabolite pathway types were also identified in this paper.

[Determination of 21 polyphenols in fruits by high performance liquid chromatography].

Objective: To establish a high performance liquid chromatography(HPLC) method for simultaneous determination of flavonoids(epicatechin, isoorientin, eriocitrin, hyperoside, narirutin, naringin, hesperidin, neohesperidin, quercetin, didymin, naringenin and hesperetin), phenolic acids(gallic acid, chlorogenic acid, caffeic acid, ferulic acid, sinapic acid and p-coumaric acid), terpenoids(limonin), stilbenes(piceatannol and resveratrol) in fruits.

Methods: Add ethanol-water(4∶1, V/V) solution to the fruit pulp sample, ultrasonic extraction at 55 ℃ for 10 min, after centrifugation, the supernatant was dried and re-dissolved, and then eluted with ZORBAX Eclipse XDB-C_(18)(4.6 mm×100 mm, 3.

MBFQuant: A Multiplier-Bitwidth-Fixed, Mixed-Precision Quantization Method for Mobile CNN-Based Applications.

Deploying Convolutional Neural Network (CNN)-based applications to mobile platforms can be challenging due to the conflict between the restricted computing capacity of mobile devices and the heavy computational overhead of running a CNN. Network quantization is a promising way of alleviating this problem. However, network quantization can result in accuracy degradation and this is especially the case with the compact CNN architectures that are designed for mobile applications.

Design of an Efficient CNN-based Cough Detection System on Lightweight FPGA.

Precisely and automatically detecting the cough sound is of vital clinical importance. Nevertheless, due to privacy protection considerations, transmitting the raw audio data to the cloud is not permitted, and therefore there is a great demand for an efficient, accurate, and low-cost solution at the edge device. To address this challenge, we propose a semi-custom software-hardware co-design methodology to help build the cough detection system.

A simple and versatile strategy for sensitive SIDA-UHPLC-MS/MS analysis of Alternaria toxins in olive oil.

Alternaria toxins are naturally occurring contaminants found in natural products. Given the prevalence of Alternaria toxins and the complexity of oil-rich matrices, achieving ultra-trace analysis has become a daunting task. A new sample pretreatment technique, i.

[Development of nutrient profiling model include nutrients and food groups evaluation].

Objective: To develop the nutrient profiling model based on the nutrition and health status of Chinese residents, and comprehensively evaluate the nutritional quality of food and dietary pattern.

Methods: Nutrient-and food group-indexes closely related to the main health problems of Chinese residents were screened and determined based on the level of evidence. Different food and dietary patterns were taken as examples to calculate the nutrient dense score.