StUdy of Gestational diabetes And Risk using Electronic Data (SUGARED): a population-based cohort study-study protocol.

Introduction: The incidence of gestational diabetes mellitus (GDM) in Australia has tripled in the last 20 years. Consequently, over 40 000 pregnancies are now diagnosed as 'higher risk' each year. This has increased antenatal surveillance and obstetric intervention, often in the form of delivery earlier than 39 weeks gestation.

Xylazine-Associated Necrotic Upper-Extremity Wounds: A Single Hospital System's Experience with 82 Patients and 125 Wounds.

Background: The rise in xylazine-adulterated heroin and fentanyl poses novel challenges to hand surgeons and a rising epidemic of necrotic upper-extremity wounds. While prior case studies have focused on particularly severe and complex xylazine-associated necrotic (XAN) wounds, the aim of this consecutive case series was to characterize the variability of presentations (ranging from mild to severe) at a single institution at the epicenter of the xylazine epidemic.

Methods: Patients presenting to a tertiary referral center for XAN upper-extremity wounds were retrospectively identified from emergency department visits and hospital admissions between January 2021 and December 2023.

Macroprolactinoma in an adolescent female with primary amenorrhoea.

Summary: Paediatric pituitary adenomas are rare in children and adolescents and differ from adults in both clinical presentation and management. We present the case of a 14-year-old female with primary amenorrhoea secondary to a macroprolactinoma, showing a modest radiological and biochemical response to dopamine agonist (DA) therapy. Despite a 10-month duration of increasing DA therapy, initial symptoms of primary amenorrhoea and hyperprolactinaemia persisted, with new symptoms of weight gain, lethargy and low mood.

Skin necrosis following digital wart intralesional injection of cantharidin.

A right-hand-dominant female presented 5 weeks following a right middle finger intralesional cantharidin injection for a common wart by a dermatologist. The patient experienced progressive stiffness, blistering, swelling, pain, and ultimately, full-thickness skin necrosis surrounding the injection site. Careful debridement followed by a full-thickness skin graft was performed with no evidence of involvement of the germinal matrix or terminal extensor tendon.

Is Butyrate Concentration in the Equine Gastrointestinal Tract Altered During and After Surgery for Treatment of Large Colon Obstruction?

A major cause of morbidity and mortality in horses with large colon obstructive lesions is injury to the colonic mucosal barrier from ischemic injury. Since butyrate has been shown to play a critical role in the maintenance of a healthy mucosal barrier, it may play a role in the recovery process. This study's objective was to determine whether the differences in butyrate concentrations existed between horses with surgical large colon obstructive lesions and healthy horses both during and after surgery.

The Performance of a Customized Generative Pre-trained Transformer on the American Society for Surgery of the Hand Self-Assessment Examination.

Introduction:  Multimodal large language models (MLLMs), such as OpenAI's ChatGPT (San Francisco, CA), have the potential to improve medical care delivery and education, although important shortcomings in accuracy and image interpretation have been noted. The aim of this study was to assess the multimodal performance of a ChatGPT model customized with hand surgery-specific knowledge.

Methods: A customized generative pre-trained transformer (GPT) was trained using peer-reviewed literature recommended by the American Society for Surgery of the Hand (ASSH).

Mesiodistal tip expression of mandibular anterior teeth in patients with mandibular incisor extraction treated with Invisalign aligners.

Introduction: Extraction of a single mandibular incisor may be prescribed in conjunction with clear aligner orthodontic treatment. The accuracy of therapeutic mesiodistal tooth positioning for the remaining mandibular anterior teeth for such patients has not been comprehensively evaluated. This retrospective study compared the predicted and achieved mesiodistal tooth movements in the mandibular anterior region for patients treated with Invisalign (Align Technology, Santa Clara, Calif), along with the influence of aligner attachments and the frequency of aligner change.

Impact of a Pulse-Enriched Human Cuisine on Functional Attributes of the Gut Microbiome Using a Preclinical Model of Dietary-Induced Chronic Diseases.

Introducing grain legumes, i.e., pulses, into any food pattern effectively increases dietary fiber and other bioactive food components of public health concern; however, the impact depends on the amount consumed.

Efficacy of planned moderate to severe torque changes in mandibular central incisors with an initial series of Invisalign aligners: a retrospective cohort study.

Objectives: To determine whether the achieved mandibular central incisor lingual root torque (LRT) changes matched the planned changes after treatment with an initial series of Invisalign aligners when ≥10° of torque change was planned.

Materials And Methods: A sample of adult patients who underwent treatment with the Invisalign appliance between 2013 and 2021 were evaluated. The pretreatment, planned, and achieved posttreatment digital models were measured using Geomagic Control X metrology software.

Comparison of the In Vitro Iron Bioavailability of Tempeh Made with to Beef and Plant-Based Meat Alternatives.

Iron is an essential mineral that supports biological functions like growth, oxygen transport, cellular function, and hormone synthesis. Insufficient dietary iron can lead to anemia and cause fatigue, cognitive impairment, and poor immune function. Animal-based foods provide heme iron, which is more bioavailable to humans, while plant-based foods typically contain less bioavailable non-heme iron.

Euler-angle norms for tooth rotation, torque and tip.

Intro: The aim of the current study was to develop and describe a new measuring system for the orientation of a tooth in a digitalized cast of a jaw and provide new angular values for the rotation, torque and tip of maxillary and mandibular teeth.

Methods: This retrospective cross-sectional study involved the utilization of a sub-group of extrinsic Euler-angles to derive optimal norm values per tooth in three different planes of orientation ('rotation', 'torque' and 'tip') by evaluating the digital representations of the teeth derived from a database containing over 17,500 patients. The process involved the entry of the .

Deep overbite reduction in adolescent patients treated with Invisalign: A retrospective analysis.

Introduction: Data regarding the efficacy of deep overbite correction with clear aligner therapy in adolescent patients are lacking. This study aimed to investigate the efficacy of deep overbite reduction in adolescent patients treated with Invisalign (Align Technology, San Jose, Calif) aligners.

Methods: This retrospective study investigated a sample of 102 patients aged 10-17 years from a large database.

Analysis of predicted and achieved root angulation changes in teeth adjacent to maxillary premolar extraction sites in patients treated with the Invisalign appliance.

Introduction: This study aimed to investigate the expression of root angulation in canine, premolar, and first molar teeth adjacent to first and second premolar extraction sites in the maxilla after treatment with an initial series of Invisalign aligners (Align Technology, Santa Clara, Calif).

Methods: Adult patients (aged ≥18 years) with at least 1 first and/or second premolar extraction in the maxilla and satisfying strict selection criteria were evaluated. Digital models representing pretreatment, predicted, and posttreatment were obtained from Align Technology's digital interface, ClinCheck.

Efficacy of planned moderate to severe torque changes in maxillary central incisors with the Invisalign appliance: A retrospective investigation.

Introduction: This study aimed to investigate whether there was a difference between the planned and achieved lingual root torque of the maxillary central incisors in patients treated with an initial series of Invisalign (Align Technology, Santa Clara, Calif) aligners in which >10° change in the inclination of these teeth was prescribed via the ClinCheck facility.

Methods: The pretreatment, planned, and the digital models after wear of the initial series of aligners regarding adult patients who satisfied selection criteria and were treated using the Invisalign appliance were measured using the Geomagic Control X software (version 2017.0.

Comparison of digital study model superimposition methods using implant-supported crowns and best-fit algorithms.

Introduction: Research regarding orthodontic changes using the superimposition of digital study models (DSMs) is commonplace. Information regarding the accuracy of data processing by superimposition software is limited. The study aimed to compare different methods of superimposing DSMs using implant-supported crowns (ISC) as a stable reference structure.

Preoperative opioid use is associated with worse two-year patient-reported outcomes after hand surgery: A retrospective cohort study.

Introduction: Opioid overprescribing has caused a substantial increase in opioid related deaths and billions of dollars in additional healthcare costs. Orthopaedic surgeons commonly prescribe opioids in the perioperative period; however, research has shown preoperative opioid use may be associated with worse postoperative outcomes. Despite this body of evidence, there are few studies investigating the association between preoperative opioid use and two-year outcomes after hand surgery.

A Cross-Sectional Survey of the Use of Clear Aligners by General Dentists in Australia.

Objectives: The primary aim of the investigation was to survey clear aligner therapy (CAT) use among general dentists in Australia. A secondary aim was to evaluate the factors that influenced general dentists in Australia not to provide CAT.

Material And Methods: General dentists registered with the Australian Health Practitioner Regulation Agency were invited to participate in a structured cross-sectional electronic survey.

Clear Aligner Therapy Concerns: Addressing Discrepancies Between Digitally Anticipated Outcomes and Clinical Ground Realities.

Expeditious strides in the fields of biomaterials, computer-aided design, and manufacturing have catapulted clear aligner therapy (CAT) to become a comprehensive orthodontic treatment modality. The efficiency of achieving planned tooth movement with clear aligners is a significant consideration while setting up the final treatment goals, as well as calculating treatment times and costs based on the available evidence. Contemporary research outcomes confirm that one of the most commonly reported clinical concerns with CAT is the discrepancy between the prescribed outcome in the digital treatment plan and the clinically achieved outcome from a given series of aligners.

Planned and achieved overjet and overbite changes following an initial series of Invisalign® aligners: A retrospective study of adolescent patients.

Objective: The aim of the present study was to compare the changes in overjet and overbite measurements achieved in adolescent patients following an initial series of Invisalign® aligners (Align Technology, San Jose, California) with those planned by orthodontists via its ClinCheck® digital treatment planning facility.

Methods: Data provided by Align regarding patients who had completed an initial series of Invisalign® aligner treatment and were less than 18-years old were assessed in relation to pre-treatment, planned and achieved overjet and overbite measurements. Descriptive statistics, Wilcoxon rank-sum, Mann Whitney calculations were computed.

The Performance of ChatGPT on the American Society for Surgery of the Hand Self-Assessment Examination.

Background: This study aims to compare the performance of ChatGPT-3.5 (GPT-3.5) and ChatGPT-4 (GPT-4) on the American Society for Surgery of the Hand (ASSH) Self-Assessment Examination (SAE) to determine their potential as educational tools.

A systematic review of the effects of maternal obesity on neonatal outcomes in women with gestational diabetes.

Maternal obesity and gestational diabetes mellitus (GDM) prevalence are increasing, with both conditions associated with adverse neonatal outcomes. This review aimed to determine the risk of adverse outcomes in women with obesity and GDM, compared with women with obesity alone. A systematic search identified 28 eligible articles.

Invisalign Lite: a cross-sectional investigation of orthodontist treatment-planning practices.

Objectives: To survey treatment-planning practices of orthodontists related to the Invisalign Lite clear aligner appliance (Align Technology, San Jose, Calif).

Materials And Methods: Patients satisfying inclusion and exclusion criteria and treated with Invisalign Lite were selected from a database containing more than 17,000 patients. Relevant data regarding treatment-planning practices were obtained from Align Technology's treatment-planning facility, ClinCheck, and evaluated.