Publications by authors named "Weiqiang Lan"
Article Synopsis
- * Berberine (BBR) shows promise for treating osteoporosis but struggles with poor solubility and instability, limiting its effectiveness.
- * Researchers developed a new nanocomplex, T-BBR, by using tetrahedral framework nucleic acids (tFNAs) to enhance the delivery of BBR, resulting in improved osteogenic and anti-osteoporosis effects through the Wnt signaling pathway.
Background: Sparc/osteonectin, cwcv and kazal-like domain proteoglycan 1 (SPOCK1) has been reported to function as an oncogene in a variety of cancer types. Increasing evidence suggests that SPOCK1 contributes to the metastatic cascade, including invasion, epithelial-mesenchymal transition (EMT) and micro-metastasis formation. As yet, however, the underlying mechanism is not clearly understood.
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