Publications by authors named "Weiqi Zai"
Angew Chem Int Ed Engl
September 2024
Article Synopsis
- Researchers developed a dual-targeting peptide, DBCO-pYCCK6, that quickly attaches to cancer cell membranes and enhances the delivery of type-I photosensitizers (PSs) for cancer treatment.
- * This method improves the labeling speed and targeting of PSs, leading to the effective generation of reactive oxygen species (ROS) upon light exposure, which induces a specific form of cell death called pyroptosis.
- * In vivo tests showed that this peptide and PS combination significantly reduced tumor growth while promoting immune responses from CD8 cytotoxic T cells, demonstrating a new approach for cancer therapy.
