[The postresuscitation changes in the permeability of the hemato-encephalic barrier and their possible pathogenetic significance].

Experiments were conducted on rats with temporary (10-min) clamping of the thoracic vascular bundle and subsequent resuscitation to study the permeability of the blood-brain barrier (BBB) to plasma albumins and globulins and to blood plasma immunoglobulins in different stages of the postresuscitation period. Mild increase of BBB permeability was detected 3 minutes after the beginning of recirculation. Permeability increased markedly in 24 hours and continued growing by the 72nd hour.