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View Article and Find Full Text PDFThe elevation of the low-temperature oxidation activity for Pt/CeO catalysts is challenging to meet the increasingly stringent requirements for effectively eliminating carbon monoxide (CO) from automobile exhaust. Although reducing activation is a facile strategy for boosting reactivity, past research has mainly concentrated on applying H as the reductant, ignoring the reduction capabilities of CO itself, a prevalent component of automobile exhaust. Herein, atomically dispersed Pt/CeO was fabricated and activated by CO, which could lower the 90% conversion temperature () by 256 °C and achieve a 20-fold higher CO consumption rate at 200 °C.
View Article and Find Full Text PDFBackground: Human society has entered the age of artificial intelligence, medical practice and medical education are undergoing profound changes. Artificial intelligence (AI) is now applied in many industries, particularly in healthcare and medical education, where it deeply intersects. The purpose of this paper is to overview the current situation and problems of "AI+medicine/medical" education and to provide our own perspective on the current predicament.
View Article and Find Full Text PDFFlorpyrauxifen-benzyl is a novel herbicide used to control weeds in paddy fields. To clarify and evaluate its hydrolytic behavior and safety in water environments, its hydrolytic characteristics were investigated under varying temperatures, pH values, initial mass concentrations and water types, as well as the effects of 40 environmental factors such as microplastics (MPs) and disposable face masks (DFMs). Meanwhile, hydrolytic products were identified by UPLC-QTOF-MS/MS, and its hydrolytic pathways were proposed.
View Article and Find Full Text PDFPorous fibers as excellent carriers can be used to prepare photoluminescence materials. Herein, cellulose nanocrystals (CNCs) were derived from microcrystalline cellulose (MCC) by sulfuric acid hydrolysis. After CNCs were squeezed into a coagulating bath containing silicon precursors obtained by the hydrolysis of tetraethyl orthosilicate, porous cellulose fibers were constructed through self-assembly and then incorporated with graphene carbon quantum dots (GQDs) to prepare porous photoluminescence cellulose fibers.
View Article and Find Full Text PDFBackground: Alcohol dependence has become a major problem that poses a serious threat to public health. Long-term heavy alcohol consumption can lead to brain functional disorders. This study aimed to investigate the relationship of the severity of cerebral white matter lesions (WMLs), serum neurofilament light (NfL) and inflammatory factors, tumour necrosis factor alpha (TNF-α) and Interleukin-1β (IL-1β), with the cognitive function of patients with alcohol dependence.
View Article and Find Full Text PDFThe reactive oxygen species (ROS) involved photocatalytic ozonation of gaseous n-hexane to heterocyclic compounds has been recently reported. However, whether such heterocyclization reaction happens on other alkanes and what is the contributing mechanism of ROS to the heterocyclic compound formation are still unclear. In present study, photocatalytic ozonation of three n-hexane's isomers (i.
View Article and Find Full Text PDFObjective: The goals of this study are to assess the correlation between 24-hour ambulatory blood pressure (BP) variability and white matter lesions (WML) in patients with cerebral small vascular disease (CSVD) and to provide guidance for the prevention of WML.
Methods: A total of 136 patients diagnosed with CSVD and essential hypertension were recruited and divided into two groups. The Fazekas scale was used to quantify the severity of WML.
Objective: This study was designed to explore the characteristics of retinal microangiopathy in patients with cerebral small vessel disease (CSVD) and clarify its interaction with the risk factors for CSVD.
Methods: Sixty patients with CSVD and 15 healthy individuals were enrolled. Demographic data, risk factors, and medical history were recorded, and magnetic resonance imaging was performed to detect and analyze the characteristics of retinal microangiopathy in the two groups.
Objective: To explore the value of brain structure magnetic resonance imaging combined with APOE-4 genotype in the early diagnosis and disease progression of elderly patients with vascular cognitive impairment no dementia (VCIND).
Methods: The first stroke patients admitted to our hospital from March 2017 to December 2018 were collected, including 130 cases of vascular cognitive impairment no dementia (VCIND group) and 50 cases of the control group (NC group). The basic information of all subjects was recorded, and APOE-4 alleles of all subjects were detected.
Background: Cerebrovascular disease is a common clinical illness. Many patients with cerebrovascular disease can be accompanied by cognitive impairment. The exosomal microRNA (miRNA)-223-3p is related to vascular endothelial injury, synaptic function, inflammatory response, and other mechanisms.
View Article and Find Full Text PDFDue to their low-symmetry lattice characteristics and intrinsic in-plane anisotropy, 2D pentagonal materials, a new class of 2D materials composed entirely of pentagonal atomic rings, are attracting increasing research attention. However, the existence of these 2D materials has not been proven experimentally until the recent discovery of PdSe . Herein, penta-PdPSe, a new 2D pentagonal material with a novel low-symmetry puckered pentagonal structure, is introduced to the 2D family.
View Article and Find Full Text PDFIt is a formidable challenge to use the traditional trial-and-error method to identify suitable catalysts for the photocatalytic degradation of volatile organic compounds (VOCs). In this work, by performing density functional theory calculations, we designed three Z-scheme g-CN/MCO (M = Hf, Zr, and Sc) heterostructures, which not only exhibit favorable structure stability but also show promising ability for photocatalytic degradation of VOCs. The enhancement of the photocatalytic activity of these three Z-scheme systems can be ascribed to the low recombination rate of electron-hole pairs because photoelectrons migrated from the g-CN layer to the MCO layer as well as the internal electric fields in the Z-scheme heterojunction.
View Article and Find Full Text PDF2D noble-transition-metal chalcogenides (NTMCs) are emerging as a promising class of optoelectronic materials due to ultrahigh air stability, large bandgap tunability, and high photoresponse. Here, a new set of 2D NTMC: Ta PdS atomic layers is developed, displaying the excellent comprehensive optoelectronic performance with an ultrahigh photoresponsivity of 1.42 × 10 A W , detectivity of 7.
View Article and Find Full Text PDFIntroduction: Neurogranin is known to be significantly elevated in patients with Alzheimer's disease (AD) and may be an effective clinical predictor of cognitive decline and neurodegeneration. Amnestic mild cognitive impairment (aMCI) is an intermediate disease state between normal cognitive ageing and dementia, the latter of which can easily revert to AD. There remains significant uncertainty regarding the conversion of aMCI to AD, and therefore, elucidating such progression is paramount to the field of cognitive neuroscience.
View Article and Find Full Text PDFThis paper uses resting-state functional magnetic resonance imaging (rs-FMRI) to construct a whole-brain binary functional network through a complex brain network analysis theory based on graph theory to explore the functional network of patients with type 2 diabetes (T2DM). Changes in topological properties and their potential relationships with fasting blood glucose (FBG), glycated haemoglobin (HbAlc), and cognitive function scale, and further explore the diagnostic value of rs-FMRI technology for central nervous system damage in T2DM patients, for clinical diagnosis and treatment Provide objective radiological evidence. In the range of sparsity (Sp) of 0.
View Article and Find Full Text PDFThis study used hydrogen proton magnetic resonance imaging to detect the changes of white matter and the medial cortex in the prefrontal cortex of patients with type 2 diabetes, analyzed its relationship with cognitive function and blood glucose level, and discussed the recognition of patients with type 2 diabetes from the perspective of brain metabolism. We discuss the neural mechanisms affected by the disorder. The experiment recruited 65 volunteers, including 32 control subjects and 33 patients with type 2 diabetes.
View Article and Find Full Text PDFThe development of a stringent sensor to detect low levels of acetone, yielding the potential for the point-of-care clinical diagnosis of diabetes, is still a great challenge but is urgently required. Most studies have focused on TiCT , yet other types of MXenes with good performance are rare. Herein, an emerging kind of MXene, VCT , has been prepared from VAlC the selective etching of the Al layer using aqueous HF at room temperature (RT), and its performance as an acetone sensor is presented.
View Article and Find Full Text PDFAlzheimer's disease (AD), the most common form of dementia, is a neurodegenerative disease characterized by neuronal atrophy in various brain regions. The expression of miR-107 is down-regulated in AD patients and target genes of miR-107 have been shown to directly involved in AD. In this study, we aimed to investigate the potential neuroprotective effects of miR-107.
View Article and Find Full Text PDFJ Geriatr Psychiatry Neurol
November 2019
As an enrichment strategy supplemented by the diagnostic framework of subjective cognitive decline (SCD), SCD identifies features that may increase the likelihood of including future-Alzheimer's disease (AD) patients. This study aimed to identify the shared and distinct atrophy patterns between patients specified by SCD and amnestic mild cognitive impairment (aMCI, a prodromal stage of AD) and to investigate the extent that automated brain magnetic resonance imaging (MRI) volumetry can differentiate patients with SCD from normal control (NC) participants and patients with aMCI. We acquired structural MRI brain scans from 44 patients with aMCI, 40 patients with SCD (who met the major criteria of SCD ), and 48 NC participants.
View Article and Find Full Text PDFBackground: Since subjective cognitive decline (SCD) was standardized in 2014, many studies have investigated its features. However, the risk of SCD () progressing to AD is much higher, and yet there have been few studies reporting the risk factors and neuropsychological assessment characteristics of SCD ().
Objective: To characterize SCD () by comparing it with normal control (NC), amnesic mild cognitive impairment (aMCI), and Alzheimer Disease (AD) regarding their demographics, lifestyle, family history of dementia, multimorbidity and the neuropsychological assessments.