Publications by authors named "Weilian Hou"
Malnutrition substantially contributes to adverse clinical outcomes. However, no national survey has been conducted to characterize its epidemiology in hospital settings in China. We conducted the China Nutrition Fundamental Data 2020 project among a multistage stratified cluster sample of adult inpatients from 291 study sites across 30 provinces, autonomous regions and municipalities (except for Hong Kong, Macao, Taiwan Province, and the Xizang Autonomous Region, please see MATERIALS AND METHODS for details of the causes) of China to generate reliable data on the prevalence of malnutrition and explore the associated risk factors.
View Article and Find Full Text PDFMMP10 alleviates non-alcoholic steatohepatitis by regulating macrophage M2 polarization.
Int Immunopharmacol
November 2023
Background: Non-alcoholic steatohepatitis (NASH), the most severe form of non-alcoholic fatty liver disease (NAFLD), is currently untreatable with a clinically validated treatment. Matrix Metallopeptidase 10 (MMP10) is a common host-response-gene involved in the immune response. However, it remains unknown whether and how MMP10 influences NASH development by modulating macrophage function.
View Article and Find Full Text PDFArticle Synopsis
- The study highlighted the significant prevalence of hospital-acquired influenza (HAI), showing it occurred in 11.38% of influenza cases, with an increase noted after 2012.
- Patients with HAI tended to be older and more likely to have chronic conditions, particularly metabolic disorders, which posed the highest risk for acquiring HAI.
- HAI cases resulted in longer hospital and ICU stays, with a higher likelihood of hospitalization and death within 30 days, indicating severe impacts on patient outcomes.