Different patterns of structural network impairments in two amyotrophic lateral sclerosis subtypes driven by F-fluorodeoxyglucose positron emission tomography/magnetic resonance hybrid imaging.

The structural network damages in amyotrophic lateral sclerosis patients are evident but contradictory due to the high heterogeneity of the disease. We hypothesized that patterns of structural network impairments would be different in amyotrophic lateral sclerosis subtypes by a data-driven method using F-fluorodeoxyglucose positron emission tomography/magnetic resonance hybrid imaging. The data of positron emission tomography, structural MRI and diffusion tensor imaging in fifty patients with amyotrophic lateral sclerosis and 23 healthy controls were collected by a F-fluorodeoxyglucose positron emission tomography/magnetic resonance hybrid.

Altered Volume and Structural Connectivity of the Hippocampus in Alzheimer's Disease and Amnestic Mild Cognitive Impairment.

: Hippocampal atrophy is a characteristic of Alzheimer's disease (AD). However, alterations in structural connectivity (number of connecting fibers) between the hippocampus and whole brain regions due to hippocampal atrophy remain largely unknown in AD and its prodromal stage, amnestic mild cognitive impairment (aMCI). : We collected high-resolution structural MRI (sMRI) and diffusion tensor imaging (DTI) data from 36 AD patients, 30 aMCI patients, and 41 normal control (NC) subjects.

Establishing a predictive model for aspirin resistance in elderly Chinese patients with chronic cardiovascular disease.

Background: Resistance to anti-platelet therapy is detrimental to patients. Our aim was to establish a predictive model for aspirin resistance to identify high-risk patients and to propose appropriate intervention.

Methods: Elderly patients (n = 1130) with stable chronic coronary heart disease who were taking aspirin (75 mg) for > 2 months were included.

[The experimental study of simvastatin on improving aspirin resistance in diabetic rats].

Objective: The purpose of the present study was to investigate the effects of the combination of aspirin, simvastatin in diabetic rat on platelet function.

Methods: Eight-week-old male Wistar rats were selected and randomly divided into diabetic group (=48) and normal control group (=48). Diabetic rats were injected with 1% STZ (65mg/kg, dissolved in 0.

Correlation between sex hormone levels and obesity in the elderly male.

Objective: To investigate the levels of sex hormones and androgen receptor (AR) in elderly male patients and to explore a possible correlation with obesity.

Methods: The cross-sectional study included 314 Elderly males (age ≥ 65 year). Of these subjects, 104 were healthy (age range 65-92 year; mean 71.

Correlation of sex hormone and androgen receptor with diabetes mellitus in elderly men.

Aim: To investigate sex hormone and androgen receptor (AR) levels and to evaluate their relationship with diabetes mellitus (DM) in senile men.

Methods: The cross-sectional study included 492 elderly men comprising 104 healthy subjects (mean age 71.4 ± 5.

[Analysis of Liqi decoction for treatment of false intestinal obstruction caused by retroperitoneal hematoma].

Objective: To study the efficiency of Liqi decoction on false intestinal obstruction caused by retroperitoneal hematoma.

Methods: Seventy-five patients were randomly divided into two groups involving Liqi groups and control group. In Liqi group, therer were 45 patients including 28 males and 17 females with an average age of (41.