Unmasking cerebral infarction: hemianopia and heavy menstrual bleeding in a patient with adenomyosis and vascular abnormalities.

Background: Adenomyosis, typically associated with heavy menstrual bleeding and pelvic pain, is rarely linked to neurological complications. This case presents a rare instance of ischemic stroke in a young patient with adenomyosis and vascular abnormalities, underscoring the role of anemia, hypercoagulability, and vascular factors as potential contributors to cerebral infarction.

Case Presentation: We describe a 41-year-old female with a history of adenomyosis who presented with right-sided hemianopia and dizziness following severe menstrual bleeding.

Swirl sign score system: a novel and practical tool for predicting hematoma expansion risk after spontaneous intracerebral haemorrhage.

Objective: To methodically analyse the swirl sign and construct a scoring system to predict the risk of hematoma expansion (HE) after spontaneous intracerebral haemorrhage (sICH).

Methods: We analysed 231 of 683 sICH patients with swirl signs on baseline noncontrast CT (NCCT) images. The characteristics of the swirl sign were analysed, including the number, maximum diameter, shape, boundary, minimum CT value of the swirl sign, and the minimum distance from the swirl sign to the edge of the hematoma.

Atomic-scale observation of calcium occupation in spinel cobalt ferrite towards the regulation of intrinsic magnetic properties.

Spinel ferrites have drawn intensive attention because of their adjustable magnetic properties by ion doping, among which calcium (Ca) is an essential dopant that is widely employed in massive production. However, its exact lattice occupation and relationship with intrinsic magnetic properties remain unclear. Here, we successfully prepared Ca-doped cobalt ferrite (CoFeO) nanoparticles by electrospinning.

A novel clinical-radscore nomogram for predicting ruptured intracranial aneurysm.

Objectives: Our study aims to find the more practical and powerful method to predict intracranial aneurysm (IA) rupture through verification of predictive power of different models.

Methods: Clinical and imaging data of 576 patients with IAs including 192 ruptured IAs and matched 384 unruptured IAs was retrospectively analyzed. Radiomics features derived from computed tomography angiography (CTA) images were selected by -test and Elastic-Net regression.

Comparison of Ruptured Intracranial Aneurysms Identification Using Different Machine Learning Algorithms and Radiomics.

Different machine learning algorithms have different characteristics and applicability. This study aims to predict ruptured intracranial aneurysms by radiomics models based on different machine learning algorithms and evaluate their differences in the same data condition. A total of 576 patients with intracranial aneurysms (192 ruptured and 384 unruptured intracranial aneurysms) from two institutions are included and randomly divided into training and validation cohorts in a ratio of 7:3.

Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram.

Hypertensive intracerebral hemorrhage (HICH) is the most common type of spontaneous intracerebral hemorrhage in China which is associated with high mortality and disability. We sought to develop and validate a noncontrast computed tomography (NCCT)-based nomogram model to achieve short-term prognostic prediction for patients with HICH. We retrospectively studied 292 patients with HICH from two medical centers, and they were divided into training ( = 151), validation ( = 66), and testing cohorts ( = 75).

FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade.

Morphologically distinct TDP-43 aggregates occur in clinically different FTLD-TDP subtypes, yet the mechanism of their emergence and contribution to clinical heterogeneity are poorly understood. Several lines of evidence suggest that pathological TDP-43 follows a prion-like cascade, but the molecular determinants of this process remain unknown. We use advanced microscopy techniques to compare the seeding properties of pathological FTLD-TDP-A and FTLD-TDP-C aggregates.

Abnormal corpus callosum induced by overt hepatic encephalopathy impairs interhemispheric functional coordination in cirrhosis patients.

Background: Although overt hepatic encephalopathy (OHE) patients were shown to have bilaterally symmetrical structural and functional abnormalities in the whole brain, few studies have focused on the bilateral cerebral hemisphere commissural fibers and measured functional coordination between bilateral hemispheres. This study aimed to investigate the structural changes of the corpus callosum (CC) and interhemispheric functional coordination in patients with OHE and to test the hypothesis that abnormal CC induced by OHE impairs interhemispheric functional coordination in cirrhosis patients.

Methods: The microstructural integrity and the volumes of each subregion of the CC were analyzed by diffusion tensor imaging (DTI) and three-dimensional T1-weighted imaging.

An individualized prediction of time to cognitive impairment in Parkinson's disease: A combined multi-predictor study.

Background: Cognitive impairment (CI) is important for the prognosis of Parkinson's disease (PD). Early prediction whether and when cognitive decline from normal cognition (NC) will occur is crucial for preventing or delaying the progression timely. The current study aimed to provide a personalized risk assessment of CI by using baseline information and establishing a multi-predictor nomogram.

Differentiating Parkinson's disease motor subtypes: A radiomics analysis based on deep gray nuclear lesion and white matter.

Objective: To investigate the feasibility of radiomics analysis of brain MR images to differentiate Parkinson's disease motor subtypes.

Methods: 42 postural instability gait difficulty (PIGD) patients, 92 tremor-dominant (TD) patients and 96 healthy controls were included from the Parkinson's Progressive Marker Initiative public database. For each subject, 4850 radiomic features from 148 cortical and 14 subcortical brain regions were extracted.

Radiomics-based classification models for HBV-related cirrhotic patients with covert hepatic encephalopathy.

Introduction: The significant abnormalities of precuneus (PC), which are associated with brain dysfunction, have been identified in cirrhotic patients with covert hepatic encephalopathy (CHE). The present study aimed to apply radiomics analysis to identify the significant radiomic features in PC and their subregions, combine with clinical risk factors, then build and evaluate the classification models for CHE diagnosis.

Methods: 106 HBV-related cirrhotic patients (54 had current CHE and 52 had non-CHE) underwent the three-dimensional T1-weighted imaging.

Aberrant brain structural network and altered topological organization in minimal hepatic encephalopathy.

Purpose: We aimed to investigate the multilevel impairments of brain structural network in patients with minimal hepatic encephalopathy (MHE).

Methods: Twenty-two patients with MHE and 22 well-matched healthy controls (HC) underwent structural magnetic resonance imaging (MRI) brain scans and neuropsychological evaluations. Individual brain structural networks were constructed using diffusion tensor imaging.

Structural Brain Network Alteration and its Correlation With Structural Impairments in Patients With Depression in and Drug-Naïve Parkinson's Disease.

Depression is common in Parkinson's disease (PD) and is correlated with the severity of motor deficits and quality of life. The present study aimed to investigate alterations in the structural brain network related to depression in Parkinson's disease (d-PD) and their correlations with structural impairments of white matter (WM). Data were acquired from the Parkinson Progression Markers Initiative (PPMI) database.

Abnormal spontaneous brain activity in minimal hepatic encephalopathy: resting-state fMRI study.

Purpose: We aimed to assess the abnormality of baseline spontaneous brain activity in minimal hepatic encephalopathy (MHE) by amplitude of low frequency fluctuation (ALFF) and fraction ALFF (fALFF).

Methods: A total of 14 MHE patients and 14 healthy controls were included in our study. Both ALFF and fALFF of functional magnetic resonance imaging were calculated for statistical analysis.

The Value of Proton Magnetic Resonance Spectroscopy in High-Intensity Focused Ultrasound Treatment of Experimental Liver Cancer.

High-intensity focused ultrasound (HIFU) is a rapidly developing, non-invasive technique for local treatment of solid tumors that produce coagulative tumor necrosis. This study is aimed to investigate the feasibility of proton magnetic resonance spectroscopy (MRS) on early assessing treatment of HIFU ablation in rabbit with VX2 liver tumor. HIFU ablation was performed on normal liver and VX2 tumor in rabbit, and MRS was performed on normal liver and VX2 tumor before and 2 days after 100% HIFU ablation or 80% ablation in tumor volume.

[1H magnetic resonance spectroscopy in the evaluation of high intensity focused ultrasound ablation for primary liver cancer].

To investigate the clinical value of 1H magnetic resonance spectroscopy (1H MRS) in the evaluation of high intensity focused ultrasound (HIFU) ablation for primary liver cancer. Routine magnetic resonance sequences, contrast-enhanced magnetic resonance imaging and respiratory-triggered single voxel point resolved spectroscopy sequence (PRESS) were performed on 24 patients with primary liver cancer before and after HIFU ablation. A respiratory-triggered axial T2 weighted imaging (T2WI) was used as localizer for PRESS.

Evaluation of short-term response of high intensity focused ultrasound ablation for primary hepatic carcinoma: utility of contrast-enhanced MRI and diffusion-weighted imaging.

Objective: To explore the significance of contrast-enhanced MRI (CE-MRI) and diffusion-weighted imaging (DWI) in evaluating the short-term response of high intensity focused ultrasound (HIFU) ablation for primary hepatic carcinoma (PHC).

Methods: Thirty-nine lesions in the livers of 27 patients were performed HIFU ablation. Conventional MRI sequences, CE-MRI and DWI were performed 1 week before HIFU and 1 week, 3 months after the therapy, respectively.

Accuracy and reliability of thyroid volumetry using spiral CT and thyroid volume in a healthy, non-iodine-deficient Chinese adult population.

Objective: The purpose of this study was to assess the accuracy and reliability of thyroid volumetry using spiral CT and to investigate thyroid volumes for a healthy, non-iodine-deficient adult population in southwestern region of China.

Materials And Methods: Spiral CT was performed in phantoms and adult subjects with normal thyroid, and the volumes were measured by observers with 5 years or more of CT experience. The phantom volumes and the thyroid volumes of all subjects were noted.

[The application of 3D liver acquisition volume acceleration integrated with array spatial sensitivity encoding technique in liver dynamic-enhancement scanning].

Objective: To evaluate the application of 3D liver acquisition volume acceleration (3D-LAVA) integrated with array spatial sensitivity encoding technique (ASSET) in liver dynamic-enhancement scanning.

Methods: One hundred forty-seven patients underwent conventional plain and contrast enhancement liver MR imaging. 3D-LAVA and 2D fast spoiled gradient recalled echo were used for contrast enhancement liver MR scanning in 90 and 57 patients respectively.