Publications by authors named "Weijia Yao"
Article Synopsis
- - Retained fetal membranes (RFM) in dairy cows is a reproductive condition related to the adhesion of placenta tissue, significantly involving collagen type IV (COL-IV) breakdown, crucial for placental expulsion.
- - The study aimed to explore the role of the focal adhesion kinase (FAK) signaling pathway in regulating COL-IV, with tissue samples collected from healthy cows and those with RFM for comparison.
- - Results showed that in RFM cows, levels of key FAK pathway proteins (FAK, Src, MMP-2, and MMP-9) were lower while COL-IV levels were higher, indicating a potential pathway disruption related to RFM that could influence future treatment strategies.
Cancer classification from the gene expression profiles by Discriminant Kernel-PLS.
J Bioinform Comput Biol
December 2010
Cancer diagnosis depending on microarray technology has drawn more and more attention in the past few years. Accurate and fast diagnosis results make gene expression profiling produced from microarray widely used by a large range of researchers. Much research work highlights the importance of gene selection and gains good results.
View Article and Find Full Text PDFThe gene of phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) has been implicated as an oncogene in ovarian cancer [L. Shayesteh et al., Nat.
View Article and Find Full Text PDFVascular endothelial growth factor (VEGF) has been implicated as a potent regulator of angiogenesis in tumors, and its protein exists as at least five isoforms with distinct biologic activities and clinical significance. Tumors under metabolic stress conditions dramatically increase VEGF expression due to both increased transcription and decreased mRNA degradation. However, it is not known how stress conditions regulate expression of each VEGF isoform.
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