ACS Appl Mater Interfaces
October 2024
Developing a high-energy-density cathode material (LiNiCoMnO, NCM) for lithium-ion batteries is crucial to the electric vehicle and energy storage industries. However, the continuous insertion/extraction of Li generates diffusion-induced stress, causing NCM particles to crack or even pulverize, leading to battery capacity loss and limiting its wider commercial application. Current experimental studies are primarily postmortem examinations, and it is difficult to capture the particle cracking evolution.
View Article and Find Full Text PDFBackground: Pectus carinatum (PC) mainly present at the growth spurt time of the early teenage years or the puberty. Poor outer appearance is a major reason for seeking help for surgeons to increase self-confidence and self-esteem. At present, minimally invasive repair (MIR) is one of effective ways to correct the chest wall deformity.
View Article and Find Full Text PDFThe first deoxygenative Heck reactions are described, as illustrated by formate-mediated -substitutions of vinyl triflates with aryl iodides. The collective data corroborate a mechanism in which Pd(OAc) and BuNI form the dianionic iodide-bridged dimer [PdI][NBu], which, under reducing conditions, serves as a precursor to the palladium(I) complex [PdI][NBu]. Dinculear oxidative addition of aryl iodide forms [PdI(Ar)][NBu], which dissociates to the monometallic complex [PdI(Ar)][NBu].
View Article and Find Full Text PDFThe first use of 1,4-pentadiene and 1,5-hexadiene as allylmetal pronucleophiles in regio-, -diastereo-, and enantioselective carbonyl addition from alcohol proelectrophiles is described. As corroborated by deuterium labeling experiments, primary alcohol dehydrogenation delivers a ruthenium hydride that affects alkene isomerization to furnish a conjugated diene, followed by transfer hydrogenative carbonyl addition. Hydrometalation appears to be assisted by the formation of a fluxional olefin-chelated homoallylic alkylruthenium complex , which exists in equilibrium with its pentacoordinate η form to enable β-hydride elimination.
View Article and Find Full Text PDFRuthenium-catalyzed hydrogen auto-transfer reactions for the direct enantioselective conversion of lower alcohols to higher alcohols are surveyed. These processes enable completely atom-efficient carbonyl addition from alcohol proelectrophiles in the absence of premetalated reagents or metallic reductants. Applications in target-oriented synthesis are highlighted, and a brief historical perspective on ruthenium-catalyzed hydrogen transfer processes is given.
View Article and Find Full Text PDFThe first enantioselective ruthenium-catalyzed carbonyl vinylations via hydrogen autotransfer are described. Using a ruthenium-JOSIPHOS catalyst, primary alcohols - and 2-butyne are converted to chiral allylic alcohols - with excellent levels of absolute stereocontrol. Notably, 1°,2°-1,3-diols participate in site-selective C-C coupling, enabling asymmetric carbonyl vinylation beyond premetalated reagents, exogenous reductants, or hydroxyl protecting groups.
View Article and Find Full Text PDFAsian J Endosc Surg
July 2021
Transdiaphragmatic duplication of digestive tract in infants is very rare. Open surgery is the main surgical treatment. We report the clinical data of a child with gastrointestinal duplication across the diaphragm who underwent thoraco-laparoscopic surgery at 12 days were retrospectively analyzed, and to explore the experience of thoraco-laparoscopic surgery in the treatment of alimentary tract duplication across the diaphragm in children, we believe minimally invasive surgical resection using thoracolaparoscopy is safe, effective and clinically feasible, focusing on the skilled use of the technique to achieve the ideal surgical effect and appearance.
View Article and Find Full Text PDFA lipase producing strain B1213 isolated from soil was identified as based on 16S rRNA gene and recA sequeence analysis, making this the first report on the presence of a lipase from . Under an aqueous two-phase purification strategy, which included (ATPE)-ion-exchange chromatography (IEC)-gel and filtration chromatography (GFC), the specific activity of the 35-kDa lipase was determined to be 875.7 U/mg protein.
View Article and Find Full Text PDFCopper has been explored as an ideal candidate for replacing noble metals in organic synthesis, especially for practical large scale preparation. Recent decades have witnessed the renaissance and improvement of copper-catalyzed and copper-mediated organic reactions. Copper nitrate is a common inorganic copper salt which has been proved to be a ubiquitous reactant in organic synthesis due to its commercial availability, stability, inexpensiveness and environmentally benign nature.
View Article and Find Full Text PDFStud Health Technol Inform
April 2015
We demonstrate how data mining techniques can help recommend effective medications when physicians need to control the glucose level of patients with type 2 diabetes. We first identify the factors that may affect physicians' medication decisions and then develop a patient-similarity based approach to automatically recommend medications for a patient with the specific condition so that his blood glucose level (measured by HbA1C value) can be well controlled. The approach is validated through experiments on real data sets and compared with the recommendations by following a clinical guideline.
View Article and Find Full Text PDFStud Health Technol Inform
April 2015
Stud Health Technol Inform
April 2015
The system of electronic medical records (EMR) has been widely used in physician practice. In China, physicians have the time pressure to provide care to many patients in a short period. Improving practice efficiency is a promising direction to mitigate this predicament.
View Article and Find Full Text PDFIn this paper, we propose a data mining method for exploring the decision-making processes of physicians from electronic patient records and test it on the medical records of patients with type-2 diabetes mellitus. This method runs in two modes: general and partitioned. In the general mode, it mines rules from the whole medical records.
View Article and Find Full Text PDFStud Health Technol Inform
April 2015
This work proposes to leverage an advanced modeling technique, namely Markov Decision Process, to evaluate sequential clinical interventions in disease management. We have demonstrated our evaluation framework on a diabetes case study over two real data sets, and discovered valuable clinical insights towards better interventions during disease progression.
View Article and Find Full Text PDFStud Health Technol Inform
April 2015
Chronic disease care, e.g., care of type 2 diabetes mellitus, is a long-term, complex process involving collaboration and coordination among multiple healthcare providers.
View Article and Find Full Text PDFMed Image Comput Comput Assist Interv
November 2010
A video recording of an examination by Wireless Capsule Endoscopy (WCE) may typically contain more than 55,000 video frames, which makes the manual visual screening by an experienced gastroenterologist a highly time-consuming task. In this paper, we propose a novel method of epitomized summarization of WCE videos for efficient visualization to a gastroenterologist. For each short sequence of a WCE video, an epitomized frame is generated.
View Article and Find Full Text PDFIEEE Trans Inf Technol Biomed
March 2009
This paper presents a new method for segmenting medical images by modeling interaction between neighboring structures. Compared to previously reported methods, the proposed approach enables simultaneous segmentation of multiple neighboring structures for improved robustness. During the segmentation process, the object contour evolution and shape prior estimates are influenced by the interactions between neighboring shapes consisting of attraction, repulsion, and competition.
View Article and Find Full Text PDFMed Image Comput Comput Assist Interv
June 2006
This paper presents a novel approach for image segmentation by introducing competition between neighboring shape models. Our method is motivated by the observation that evolving neighboring contours should avoid overlapping with each other and this should be able to aid in multiple neighboring objects segmentation. A novel energy functional is proposed, which incorporates both prior shape information and interactions between deformable models.
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