Heterogeneous Interface Design with Oxygen Vacancy-Rich Assistance High-Capacity Titanium-Based Oxide Anode Materials for Sodium-Ion Batteries.

Researchers are paying more attention to sodium-ion batteries (SIBs) because of their abundant supply of sodium resources and affordable price. TiO offers excellent safety and a long lifespan as an anode material for SIBs. However, the process kinetics is slow due to its limited Na storage efficiency, weak conductivity, and irreversible Na capture.

UBE2M forms a positive feedback loop with estrogen receptor to drive breast cancer progression and drug resistance.

UBE2M, a NEDD8-conjugating enzyme, is dysregulated in various human cancers and promotes tumor cell proliferation. However, its role in estrogen receptor-positive (ER) breast cancer remains unknown. We found that UBE2M expression was significantly higher in ER breast cancer tissues than in ER-negative (ER) breast cancer tissues.

Highly Reversible and Dendrite-Free Zinc Anodes Enabled by PEDOT Nanowire Interfacial Layers for Aqueous Zinc-Ion Batteries.

The aqueous zinc-ion batteries (ZIBs) have gained increasing attention because of their high specific capacity, low cost, and good safety. However, side reactions, hydrogen evolution reaction, and uncontrolled zinc dendrites accompanying the Zn metal anodes have impeded the applications of ZIBs in grid-scale energy storage. Herein, the poly(3,4-ethylenedioxythiophene) (PEDOT) nanowires as an interfacial layer on the Zn anode (Zn-PEDOT) are reported to address the above issues.

Inhibitory Effect of Evodiamine on Psoriasis Lesions and Itching in Mice.

Purpose: This study seeks to investigate the effect of evodiamine on psoriasis and psoriatic pruritus.

Methods: Imiquimod-induced psoriasiform dermatitis in mice was used as a model, and evodiamine was topically applied for seven days. The mice were observed daily for skin damage on the back, clinical score and their scratching behavior was recorded.

Enabling Further Organic Electrolyte Infiltration of Cellulose-Based Separators Defect-Rich Polypyrrole Modification for High Sodium Ion Transport in Sodium Metal Batteries.

Sodium metal batteries (SMBs) have high-density and cost-effective characteristics as one of the energy storage systems, but uncontrollable dendrite growth and poor rate performance still hinder their practical applications. Herein, a nitrogen-rich modified cellulose separator with released abundant ion transport tunnels in organic electrolyte was synthesized by in situ polymerization of polypyrrole, which is based on the high permeability of cellulose in aqueous solution and the interfacial interaction between cellulose and polypyrrole. Meanwhile, the introduction of abundant structural defects such as branch chains, oxygen-containing functional groups, and imine-like structure to disrupt polypyrrole conjugation enables the utilization of conductive polymers in composite separator applications.

Orbital angular momentum holographic multicasting for switchable and secure wireless optical communication links.

The physical dimension of orbital angular momentum (OAM) states of light has been successfully implemented as information carrier in wireless optical communication (WOC) links. However, the current OAM data coding strategies in WOC are mainly limited to the temporal domain, rarely involving the degree of freedom of spatial domain to transmit an image directly. Here, we apply OAM holographic multiplexing technology for spatial information encoding in WOC links.

Long-Cycle-Life Sodium-Ion Battery Fabrication via a Unique Chemical Bonding Interface Mechanism.

Titanates have been widely reported as anode materials for sodium-ion batteries (SIBs). However, their wide temperature suitability and cycle life remain fundamental issues that hinder their practical application. Herein, a novel hollow Na Ti O microsphere (H-NTO) with a unique chemically bonded NTO/C(N) interface is reported.

Dual Doping of Titania for Enhanced Na Storage Performance.

The sluggish sodium-ion diffusion kinetics and low electronic conductivity have severely restricted the development of the TiO anode for sodium-ion batteries. Defect engineering, such as single-heteroatom doping and oxygen vacancies, has proven to be effective methods to improve the conductivity of TiO, but a comprehensive understanding of the synergistic effect of dual-heteroatom doping and oxygen vacancies on the sodium storage performance of TiO is still lacking. Herein, we design a synergistic strategy of dual doping via the in situ doping and hydrogenation treatment to improve conductivity and cycling stability of TiO.

768-ary Laguerre-Gaussian-mode shift keying free-space optical communication based on convolutional neural networks.

Beyond orbital angular momentum of Laguerre-Gaussian (LG) modes, the radial index can also be exploited as information channel in free-space optical (FSO) communication to extend the communication capacity, resulting in the LG- shift keying (LG-SK) FSO communications. However, the recognition of radial index is critical and tough when the superposed high-order LG modes are disturbed by the atmospheric turbulences (ATs). In this paper, the convolutional neural network (CNN) is utilized to recognize both the azimuthal and radial index of superposed LG modes.

Porous Sb with three-dimensional Sb nanodendrites as electrode material for high-performance Li/Na-ion batteries.

The increasing demand in energy consumption and the use of clean energy from sustainable energy sources have driven the research in the development of advanced materials for Li-ion and Na-ion batteries. In this work, we have developed a simple technique to synthesize a porous Sb structure through a galvanic replacement reaction between Sb and Zn particles. The porous Sb structure consists of a three-dimensional-hierarchical structure with tree-like nanoscale Sb dendrites.

Sb nanocrystal-anchored hollow carbon microspheres for high-capacity and high-cycling performance lithium-ion batteries.

There is a great need to develop sustainable and clean energy storage devices and systems of high-energy and high-capacity densities. In this work, we synthesize antimony (Sb) nanocrystal-anchored hollow carbon microspheres (Sb@HCMs) via the calcination of cultivated yeast cells and the reduction of SbCl in an ethylene glycol solution on the surface of hollow carbon microspheres. The Sb@HCMs possess hollow and porous structure, and the Sb is present in the form of nanocrystals.

Nano Pd-Decorated Manganese Dioxide Nanosheets for Effective Photothermal Chemotherapy.

A drug delivery system based on the palladium and manganese dioxide composite (FP-Pd@MnO) is designed and prepared for the first time. The FP-Pd@MnO allows doxorubicin (DOX) loading as high as 58% in weight. The rapid release of DOX from FP-Pd@MnO is regulated via pH reduction, ascending glutathione concentration, and near-infrared (NIR) stimulus, which is advantageous to control drug release in the tumor site.

Synthesis and Evaluation of Aminothiazole Derivatives as Hedgehog Pathway Inhibitors.

A series of aminothiazole derivatives bearing the benzimidazole moiety were synthesized and evaluated in Gli luciferase reporter assays. Lead optimization led to the discovery of potent hedgehog pathway antagonist 18 (2-[3-(1H-benzimidazol-2-yl)-4-chloroanilino]-N-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxamide), with IC values in nanomolar range. The molecular basis ascribed to hindering sonic hedgehog-driven Smoothened (Smo) localization within the primary cilium (PC).

Lycofargesiines A-F, further Lycopodium alkaloids from the club moss Huperzia fargesii.

Six undescribed Lycopodium alkaloids (LAs) comprising four lycodine-type (lycofargesiines A-D), one lycopodine-type (lycofargesiine E), and a phlegmarine-type (lycofargesiine F), together with 16 known ones were isolated from the club moss Huperzia fargesii. Their structures and absolute configurations were determined by extensive spectroscopic methods, electronic circular dichroism (ECD) analysis, and density functional theory (DFT) calculations. (7S,8R,12R,13R)-Lycofargesiine A is a rare naturally occurring LA possessing an exocyclic double bond between C-15 and C-16, with ring A being a rare 2,3-dihyropyridone motif.

Nonenzymatic glucose sensor based on Ag&Pt hollow nanoparticles supported on TiO nanotubes.

This study was dedicated to develop a nonenzymatic glucose sensor based on Ag&Pt hollow nanoparticles supported on TiO nanotubes. The Ag&Pt-TiO/(500°C) was synthesized by a simple reduction and galvanic replacement method in an aqueous solution. The surface morphology and structure of Ag&Pt-TiO/(500°C) could be examined by transmission electron microscopy, scanning electron microscopy and energy dispersive spectrometer.