Brownian non-Gaussian polymer diffusion in non-static media.

In nature, essentially, almost all the particles move irregularly in non-static media. With the advance of observation techniques, various kinds of new dynamical phenomena are detected, e.g.

Energy-Level Alignment at TiO@NH-MIL-125 Interface for High-Performance Gas Sensing.

Metal oxide (MO)-based chemiresistive sensors have great potential in environmental monitoring, security protection, and disease diagnosis. However, the thermally activated sensing mechanism in pristine MOs leads to high working temperature and poor selectivity, which are the main challenges impeding practical applications. Precise modulation of the band structure at the heterojunction interfaces of MOs offers the opportunity to unlock unique electrical and optical properties, enabling us to overcome these challenges.

A smartphone-based supramolecular biosensor for portable and rapid detection of buprofezin in real food samples.

Buprofezin (BUP) is an insect growth regulator widely used in agriculture to control hemipteran pests, particularly the melon aphid, Aphis gossypii, due to its efficiency and low toxicity. Although approved by the Chinese government, its maximum residue limit (MRL) in food is strictly regulated, and conventional techniques for detecting BUP have several limitations. Our study reports successful BUP detection using a supramolecular fluorescent probe DP@ALB, constructed with chalcone-based fluorescent dye DP and albumin as the host.

Boosting smartphone-assisted on-site monitoring capacity for nitroxynil using synergistic fluorescent sensing system.

A novel ratiometric analytical method based on a quantum dot (QD)-integrated supramolecular sensing system successfully achieves the portable on-site detection of nitroxynil.

Discovering Facet-Dependent Formation Kinetics of Key Intermediates in Electrochemical Ammonia Oxidation by a Electrochemiluminescence Active Probe.

Facile evaluation of formation kinetics of key intermediate is crucial for a comprehensive understanding of electrochemical ammonia oxidation reaction (AOR) mechanisms and the design of efficient electrocatalysts. Currently, elucidating the formation kinetics of key intermediate associated with rate-determining step is still challenging. Herein, 4-phtalamide-N-(4'-methylcoumarin) naphthalimide (CF) is developed as a molecular probe to detect NH intermediate during AOR via electrochemiluminescence (ECL) and further investigated the formation kinetics of NH on Pt catalysts with different crystal planes.

Harnessing a simple ratiometric fluorescent probe for albumin recognition and beyond.

A commercially available naphthalene fluorophore serves as a ratiometric indicator for albumin, showcasing its applications in albumin-based supramolecular recognition.

Anti-cancer drug axitinib: a unique tautomerism-induced dual-emissive probe for protein analysis.

A commercial anti-cancer drug, axitinib, exhibits very stable dual emissions for discrimination of human serum albumin.

A novel dual-color fluorescent sensor with two pKas for on-site detection of pH in food.

Tracking pH fluctuations in food samples is important for ensuring food freshness. Fluorescent probes have been widely applied as promising tools for the on-site detection of pH changes; however, most of them can be applied only at either lower or higher pH ranges because their response structures commonly have a single acid dissociation constant (pKa). To address this problem, we designed a fluorescent sensor, called HMB, containing a methylpiperazine group with two pKa values, which exhibited a unique dual-color response to pH changes over a wide pH range.

Melt-quenched glass formation of a family of metal-carboxylate frameworks.

Metal-organic framework (MOF) glasses are an emerging class of glasses which complement traditional inorganic, organic and metallic counterparts due to their hybrid nature. Although a few zeolitic imidazolate frameworks have been made into glasses, how to melt and quench the largest subclass of MOFs, metal carboxylate frameworks, into glasses remains challenging. Here, we develop a strategy by grafting the zwitterions on the carboxylate ligands and incorporating organic acids in the framework channels to enable the glass formation.

Rational design of a FA1-targeting anti-interference fluorescent probe for the point-of-care testing of albuminuria.

Albuminuria is a crucial urine biomarker of human unhealthy events such as kidney diseases, cardiovascular diseases, and diabetes. However, the accurate diagnosis of albuminuria poses a significant challenge owing to the severe interference from urine fluorescence and urine drugs. Here, we report a novel flavone-based fluorescent probe, DMC, by incorporating the FA1-targeting methylquinazoline group into a flavone skeleton with the extend π-conjugation.

Legacy and emerging per- and polyfluoroalkyl substances in the Shuidong bay of South China: Occurrence, partitioning behavior, and ecological risks.

With the phase-out of legacy per- and polyfluoroalkyl substances (PFASs), PFAS alternatives have been increasingly used in industrial production and daily life. However, available information on the occurrence of PFASs and PFAS alternatives in semi-enclosed bays remains limited. As a representative semi-enclosed bay in Guangdong Province, China, Shuidong Bay has experienced severe anthropogenic pollution (industrial, shipping, cultural, and domestic) in recent decades.

Photo Responsive Electron and Proton Conductivity within a Hydrogen-Bonded Organic Framework.

Rational design of crystalline porous materials with coupled proton-electron transfer has not yet been reported to date. Herein, we report a donor-acceptor (D-A) π-π stacking hydrogen-bonded organic framework (HOF; HOF-FJU-36) with zwitterionic 1,1'-bis(3-carboxybenzyl)-4,4'-bipyridinium (H L ) as acceptor and 2,7-naphthalene disulfonate (NDS ) as donor to form a two-dimensional (2D) layer. Three water molecules were situated in the channels to connect with acidic species through hydrogen bonding interactions to give a 3D framework.

A Humidity-Induced Large Electronic Conductivity Change of 10 on a Metal-Organic Framework for Highly Sensitive Water Detection.

The electronic conductivity (EC) of metal-organic frameworks (MOFs) is sensitive to strongly oxidizing guest molecules. Water is a relatively mild species, however, the effect of H O on the EC of MOFs is rarely reported. We explored the effect of H O on the EC in the MOFs (NH ) -MIL-125 and its derivatives with experimental and theoretical investigations.

Illustrating new understanding of adsorbed water on silica for inducing tetrahedral cobalt(II) for propane dehydrogenation.

Highly dispersed metal sites on the surface of silica, achieved from immobilization of metal precursor within hydroxyl groups, has gained increasing attention in the field of heterogeneous catalyst. However, the special role of adsorbed water derived by hydroxyl groups on the silica is generally ignored. Herein, a new understanding of adsorbed water on the formation of highly dispersed tetrahedral Co(II) (T-cobalt(II)) sites is illustrated.

Hydrogen Bond Activation by Pyridinic Nitrogen for the High Proton Conductivity of Covalent Triazine Framework Loaded with H PO.

Under high temperature anhydrous conditions, it is still a formidable challenge to improve the performance of proton-conducting materials based on H PO and elucidate its proton conduction mechanism. Herein, a highly stable covalent triazine frameworks (CTFs) based on H PO is reported. The more pyridinic nitrogen CTFs contain, the higher proton conductivity is.

The Growth Mechanism of a Conductive MOF Thin Film in Spray-based Layer-by-layer Liquid Phase Epitaxy.

The layer-by-layer liquid-phase epitaxy (LBL-LPE) method is widely used in preparing metal-organic framework (MOF) thin films with the merits of controlling thickness and out-of-plane orientation for superior performances in applications. The LBL-LPE growth mechanism related to the grain boundary, structure defect, and orientation is critical but very challenging to study. In this work, a novel "in-plane self-limiting and self-repairing" thin-film growth mechanism is demonstrated by the combination study of the grain boundary, structure defect, and orientation of Cu (HHTP) -xC thin film via microscopic analysis techniques and electrical measurements.

LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.

Background: Beryllium and its compounds are carcinogenicity, but the mechanisms through which this occurs have yet to be clarified. Accumulating evidence exists that long noncoding RNAs (lncRNAs) play an important role in occurrence and development of cancer.

Aims And Methods: To explore the carcinogenic mechanism of beryllium, human bronchial epithelial cells (16HBE) were treated with 50 μM beryllium sulfate (BeSO) for 45 passages (~23 weeks).

METTL3 plays a crucial function in multiple biological processes.

The N6-methyladenosine (mA) refers to the methylation of the N6 position of adenosine of RNA adenine. The modification of mA is one of the most abundant epigenetic modifications in eukaryotic mRNA and non-coding RNA and is controlled by methyltransferases and demethylases. The biological mechanism and significance of mA have been discovered with the development of mA sequencing.

Whole transcriptome analysis of long noncoding RNA in beryllium sulfate-treated 16HBE cells.

Beryllium and its compounds can cause pulmonary interstitial fibrosis through mechanisms that are not yet clear. Long non-coding RNA (lncRNA) is implicated in various diseases. The molecular toxicity of beryllium sulfate (BeSO) was investigated through the RNA-seq analysis of the lncRNA and mRNA whole-transcriptome of BeSO-treated 16HBE cells.

Identifying molecular functional groups of organic compounds by deep learning of NMR data.

We preprocess the raw nuclear magnetic resonance (NMR) spectrum and extract key features by using two different methodologies, called equidistant sampling and peak sampling for subsequent substructure pattern recognition. We also provide a strategy to address the imbalance issue frequently encountered in statistical modeling of NMR data set and establish two conventional support vector machine (SVM) and K-nearest neighbor (KNN) models to assess the capability of two feature selections, respectively. Our results in this study show that the models using the selected features of peak sampling outperform those using equidistant sampling.

Ellagic acid attenuates beryllium sulphate-induced oxidative stress and histopathological alterations of spleen in rats.

Context: Ellagic acid (EA) is a phenolic constituent in certain fruits and has largely been recognized for its role as an antioxidant compound.

Objective: To evaluate the effect of EA on beryllium sulphate-induced splenic toxicity in rats.

Materials And Methods: Male Sprague-Dawley rats were divided into four groups.

Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.

Inhalation of beryllium and its compounds can cause lung injuries, resulting from inflammation and oxidative stress. Multivesicular bodies (MVB), such as exosomes, are membrane vesicles produced by early and late endosomes that mediate intercellular communications. However, the role of exosomes in beryllium toxicity has not been elucidated.

Lévy Walk Dynamics in an External Constant Force Field in Non-Static Media.

Based on the recognition of the huge change of the transport properties for diffusion particles in non-static media, we consider a Lévy walk model subjected to an external constant force in non-static media. Since the physical and comoving coordinates of non-static media are related by scale factor, we equivalently transfer the process from physical coordinate into comoving coordinate and derive the master equation governing the probability density function of the position of the particles in comoving coordinate. Utilizing the Hermite orthogonal polynomial expansions, some statistical properties are obtained, including the asymptotic behaviors of the first two moments in both coordinates and kurtosis.