Publications by authors named "Weihao Mu"
Article Synopsis
- The study aims to explore how lncRNA SNHG12 influences the transition of macrophages to myofibroblasts in cancer-associated fibroblast-derived extracellular vesicles in non-small cell lung cancer (NSCLC).
- Researchers isolated extracellular vesicles from NSCLC tissue and examined their composition, while also investigating the interactions among lncRNA SNHG12, miR-181a-5p, and Smad3.
- The findings revealed that lncRNA SNHG12 promotes the transformation of M2 macrophages into myofibroblasts, significantly increasing Smad3 expression through its interaction with miR-181a-5p.
Effect of hepatocyte growth factor on mice with hypoxic pulmonary arterial hypertension: a preliminary study.
Zhongguo Dang Dai Er Ke Za Zhi
August 2022
Objectives: To study the association between hepatocyte growth factor (HGF) and treatment response in mice with hypoxic pulmonary arterial hypertension (HPAH) and the possibility of HGF as a new targeted drug for HPAH.
Methods: After successful modeling, the HPAH model mice were randomly divided into two groups: HPAH group and HGF treatment group (tail vein injection of recombinant mouse HGF 1 mg/kg), with 10 mice in each group. Ten normal mice were used as the control group.
To study the effects of aluminum alloys processed by a laser in air and water and at different water velocities, corresponding experiments were conducted and the impacting effects of different water velocities on the surface of the workpiece were simulated, respectively. The results show that when laser processing aluminum alloy materials in air, there is more slag and a recondensation layer on both sides of the groove, the heat-affected zone is larger and the surface processing quality is poor. When laser processing aluminum alloy materials in water, the processing quality is improved.
View Article and Find Full Text PDFThis paper studies the compound effect of liquid medium and laser on the workpiece and analyses the law of material surface temperature change during the processing. Taking 7075-T6 aluminum alloy as the research object, the surface temperature field of aluminum alloy processed using water-jet-assisted laser machining under different process parameters was simulated using finite element software. In addition, the temperature field of the material surface was detected in real-time using the self-built water-jet-assisted laser machining temperature field detection system, and the processing results were observed and verified using an optical microscope, scanning electron microscope, and energy spectrum analyzer.
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