Temporal Analysis Reveals the Transient Differential Expression of Transcription Factors That Underlie the Trans-Differentiation of Human Monocytes to Macrophages.

The activation of monocytes and their trans-differentiation into macrophages are critical processes of the immune response. Prior work has characterized the differences in the expression between monocytes and macrophages, but the transitional process between these cells is poorly detailed. Here, we analyzed the temporal changes of the transcriptome during trans-differentiation of primary human monocytes into M0 macrophages.

Gravity-driven high flux filtration behavior and microbial community of an integrated granular activated carbon and dynamic membrane bioreactor for domestic wastewater treatment.

A gravity-driven dynamic membrane bioreactors (DMBR) with GAC addition (G-DMBR) was operated under constant pressure filtration mode (using 20 cm water head) for real domestic wastewater treatment. During the stable operation period, the treatment performance, DM filtration behavior and mechanism as well as microbial properties were studied and compared with a control DMBR (C-DMBR). Both DMBRs showed stable removal of chemical oxygen demand (COD) and ammonia (NH-N) with average removal rates over 88% and 98%, respectively.