Synergistic effect of corn straw and mulberry leaves fermantation in vitro and effects on growth performance and antioxidant capacity of sheep.

This study was to determine the synergistic effect of corn straw and mulberry leaves in sheep diet. Corn straw and mulberry leaves were mixed as culture substrate for six groups: 100:0 (T0), 80:20 (T20), 60:40 (T40), 40: 60 (T60), 20:80 (T80) and 0:100 (T100). The in vitro culture indicated that mulberry leaves exhibited a positive correlation with theoretical gas production (GP), cumulative GP, microbial crude protein concentration, and organic matter digestibility.

Integrative transcriptogenomic analyses reveal a regulatory network of rice eating and cooking quality and unveil a role of alpha-globulin in modulating starch and sucrose metabolism.

Rice eating and cooking quality (ECQ) is significantly influenced by the physicochemical properties of its starch. This study integrates whole-genome resequencing, transcriptomic data, and phenotypic analysis to identify the genetic factors that regulate transcript expression levels and contribute to phenotypic variation in rice ECQ traits. A TWAS (transcriptome-wide association study) identified 285 transcripts linked to six ECQ traits.

A multifunctional hydrogel of cellulose nanofiber/microfibrillated cellulose hierarchical network for photothermal antibacterial and all-solid supercapacitor assembly.

In recent years, flexible-hydrogel wearable devices have undergone rapid development while photothermal therapy, energy storage/conversion, and other fields have been widely developed and used. However, the poor mechanical properties of hydrogels can affect their stability and reliability in practical applications, and it is often difficult to achieve both excellent mechanical properties and multifunctional characteristics. This study prepared a hierarchical cellulose network/PVA multifunctional composite hydrogel (MCPH) using cellulose nanofiber as fine fibers and microfibrillated cellulose as coarse fibers.

A flexible multifunctional sensor with a conductive network based on silk nanofibers and MXene for monitoring physiological activity, capacitive pens, photothermal conversion and antibacterial.

Flexible electronic sensors that can capture subtle physical, chemical and biological signals and generate real-time stimulus responses are of great importance in the fields of human-computer interaction, biomedicine, etc. Herein, a multifunctional sensing hydrogel was developed by tightly adhering two-dimensional rigid conductive MXene nanosheets to the surface of vimineous silk nanofibers (SNFs) and assembling them into an SNF@MXene network structure. Polyvinyl alcohol (PVA) was then in situ polymerized in SNF@MXene as a filling matrix.

Marein alleviates the development of atherosclerosis through targeting miR-126/lipoprotein-associated phospholipase A axis.

As a classical precious medicine, Coreopsis tinctoria Nutt. (C. tinctoria) is widely utilized for treatment of cardiometabolic diseases, while the important compound of C.

High-efficiency mass-transfer Marangoni cellulose hydrogel reactor for the degradation of pollutants.

Noble metal nanoparticles have been widely used in catalysis, environmental studies, and other fields. However, the loading of noble metals is challenging because of their unfavorable mass transfer. Herein, a simple, green dual-template method was developed for the synthesis of a Marangoni cellulose hydrogel rotor catalytic reactor (MCR).

Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function.

In periparturient dairy cows, high non-esterified fatty acids (NEFAs) caused by a severe negative energy balance induce oxidative stress and metabolic dysfunction, which pose a severe challenge to the dairy industry. Resveratrol (RES) is a polyphenolic compound with antioxidant, anti-inflammatory and multiple other physiological effects. However, its effect on oxidative damage triggered by NEFAs in bovine mammary epithelial cells is rarely reported.

Biological Characteristics and Fungicide Screening of Causing Mulberry Anthracnose.

Mulberry is an important economic crop in China that is widely planted and has important edible and medicinal value. Anthracnose, a critical leaf disease, severely compromises the yield and quality of mulberry trees. However, there are many kinds of pathogens causing mulberry anthracnose and it is difficult to control.

High-performance supercapacitors based on coarse nanofiber bundle and ordered network hydrogels.

Most of the developed flexible hydrogel supercapacitors struggle to maintain their electrochemical stability and structural integrity under tensile strain. Therefore, developing a flexible supercapacitor with excellent mechanical properties and stable electrochemical performance under different strains remains a challenge. Based on the previous cartilage-like structure, we designed a new coarse nanofiber bundle and ordered network.

Effects of 1-Deoxynojirimycin Extracts of Mulberry Leaves on Oxidative Stress and the Function of the Intestinal Tract in Broilers Induced by HO.

The poultry industry struggles with oxidative stress affecting gut health and productivity. This study examined using 1-Deoxynojirimycin (DNJ) extracts from mulberry leaves as an antioxidant in broilers feed to combat this issue. We divided 240 broilers, aged 16 days, into six groups, including a control and groups exposed to oxidative stress through HO injections, with different supplement levels of DNJ-E (40, 80, 120, and 160 mg/kg of the basal diet) lasting until the broilers reached 42 days old.

Thermostability improvement of the glucose oxidase from Penicillium amagasakiense for efficient antimicrobial performance through computer-aided molecular design.

Glucose oxidases (GODs) induce the catalyzation from β-d-glucose to gluconic acid in an oxygen-consuming process, providing a potential antibiotic substitution strategy. However, the inadequate properties of existing GODs in parallel hinder the antimicrobial capacity for industrial applications. In this study, PaGOD (WT) from Penicillium amagasakiense was enzymatically improved through computer-aided design based on energy optimization.

Effect of electro-stimulated Bacillus subtilis and Lactobacillus casei on ensiling quality, anti-nutrients, and bacterial community of mulberry leaf silage.

Background: There are few studies on the effects of electrically stimulated bacteria on anti-nutritional factors and microbial communities in mulberry leaf silage. This study aimed to examine the impact of the combined use of electrically stimulated Bacillus subtilis (EB) and Lactobacillus casei (LC) on the quality and degradation of anti-nutritional factors in mulberry leaf silage.

Results: The results revealed that the synergistic effect of EB and LC significantly enhanced the nutritional value of mulberry leaves, as evidenced by the promotion of lactic acid synthesis, the reduction of anti-nutritional factors, and the augmentation of lactic acid bacteria following a 60-day silage period.

The Mechanism of the Development and Maintenance of Sexual Dimorphism in the Dioecious Mulberry Plant ().

Intersexual differentiation is crucial for the speciation and maintenance of dioecious plants, but the underlying mechanisms, including the genes involved, are still poorly understood. Here, we focused on a typical dioicous plant , to explore the molecular footprints relevant to sex evolution by revealing the differentially expressed genes (DEGs) between two sexes and the testing signals of selection for these DEGs. From the results, we found a total of 1543 DEGs.

Metabolomics and physio-chemical analyses of mulberry plants leaves response to manganese deficiency and toxicity reveal key metabolites and their pathways in manganese tolerance.

Introduction: Manganese (Mn) plays a pivotal role in plant growth and development. Aside aiding in plant growth and development, Mn as heavy metal (HM) can be toxic in soil when applied in excess. is an economically significant plant, capable of adapting to a range of environmental conditions and possessing the potential for phytoremediation of contaminated soil by HMs.

UFL1 regulates cellular homeostasis by targeting endoplasmic reticulum and mitochondria in NEFA-stimulated bovine mammary epithelial cells via the IRE1α/XBP1 pathway.

Elevated levels of NEFA caused by negative energy balance in transition cows induce cellular dyshomeostasis. Ubiquitin-like modifier 1 ligating enzyme 1 (UFL1) can maintain cellular homeostasis and act as a critical regulator of stress responses besides functioning in the ubiquitin-like system. The objective of this study was to elucidate the UFL1 working mechanism on promoting cellular adaptations in bovine mammary epithelial cells (BMECs) in response to NEFA challenge, with an emphasis on the ER and mitochondrial function.

Comparative Physio-Biochemical and Transcriptome Analyses Reveal Contrasting Responses to Magnesium Imbalances in Leaves of Mulberry ( L.) Plants.

Magnesium (Mg) deficiency is a major factor limiting the growth and development of plants. Mulberry ( L.) is an important fruit tree crop that requires Mg for optimal growth and yield, especially in acid soils.

Microvascular Decompression Plus Partial Resection of Trigeminal Nerve Motor Root for Hemimasticatory Spasm Combined With Hemifacial Atrophy: A Good Choice or Not?

Hemimasticatory spasm (HMS) combined with hemifacial atrophy is a rare clinical entity with an unclear etiology. The authors report a 58-year-old female suffering from HMS and hemifacial atrophy, which performed microvascular decompression plus partial resection of the trigeminal nerve motor root, which is the first report in worldwide. The vascular compression of the trigeminal nerve motor root was found in surgery, the authors completed the aforementioned surgical method.

Predicting rectal cancer prognosis from histopathological images and clinical information using multi-modal deep learning.

Objective: The objective of this study was to provide a multi-modal deep learning framework for forecasting the survival of rectal cancer patients by utilizing both digital pathological images data and non-imaging clinical data.

Materials And Methods: The research included patients diagnosed with rectal cancer by pathological confirmation from January 2015 to December 2016. Patients were allocated to training and testing sets in a randomized manner, with a ratio of 4:1.

Genome-Wide Analysis of the Xyloglucan Endotransglucosylase/Hydrolase () Gene Family: Expression Pattern during Magnesium Stress Treatment in the Mulberry Plant ( L.) Leaves.

Mulberry ( L.), a significant fruit tree crop, requires magnesium (Mg) for its optimal growth and productivity. Nonetheless, our understanding of the molecular basis underlying magnesium stress tolerance in mulberry plants remains unexplored.

Decoding the effects of varied peer victimization forms on depression and anxiety among Chinese adolescents: An exploration through latent transition analysis.

This study aims to examine co-occurrence patterns of depression and anxiety among Chinese adolescents and their associations with various forms of peer victimization. We collected longitudinal data from 1005 middle school students using the Multidimensional Peer Victimization Scale, Center for Epidemiological Studies Depression Scale, and State-Trait Anxiety Inventory. Then we conducted latent profile analysis, latent transition analysis, and logistic regression analysis.

Alternations of Blood Pressure Following Surgical or Drug Therapy for Prolactinomas.

Several subtypes of pituitary neuroendocrine tumors (PitNETs), such as acromegaly and Cushing's disease, can result in hypertension. However, whether prolactinoma is associated with this complication remains unknown. Moreover, the effect of treatment with surgery or drugs on blood pressure (BP) is unknown.

Associations of nirmatrelvir-ritonavir treatment with death and clinical improvement in hospitalized patients with COVID-19 during the Omicron wave in Beijing, China: a multicentre, retrospective cohort study.

Background: The effectiveness of nirmatrelvir-ritonavir has mainly been shown in non-hospitalized patients with mild-to-moderate coronavirus disease 2019 (COVID-19). The real-world effectiveness of nirmatrelvir-ritonavir urgently needs to be determined using representative in-hospital patients with COVID-19 during the Omicron wave of the pandemic.

Methods: We performed a multicentre, retrospective study in five Chinese PLA General Hospital medical centers in Beijing, China.

Optimizing the Probabilistic Neural Network Model with the Improved Manta Ray Foraging Optimization Algorithm to Identify Pressure Fluctuation Signal Features.

To improve the identification accuracy of pressure fluctuation signals in the draft tube of hydraulic turbines, this study proposes an improved manta ray foraging optimization (ITMRFO) algorithm to optimize the identification method of a probabilistic neural network (PNN). Specifically, first, discrete wavelet transform was used to extract features from vibration signals, and then, fuzzy c-means algorithm (FCM) clustering was used to automatically classify the collected information. In order to solve the local optimization problem of the manta ray foraging optimization (MRFO) algorithm, four optimization strategies were proposed.