A multimodal fluorescent probe for portable colorimetric detection of pH and it's application in mitochondrial bioimaging.

Mitochondria, as vital energy supplying organelles, play important roles in cellular metabolism, which are closely related with mitochondrial pH (∼8.0). In this work, a novel multimodal fluorescent probe was employed for ratiometric and colorimetric detection of pH.

A two-photon multi-emissive fluorescent probe for discrimination of Cys and Hcy/GSH via an aromatic substitution-rearrangement.

Cys (Cysteine), Hcy (homocysteine), and GSH (glutathione) are three important kinds of biothiols, playing crucial roles in the variety of pathological and physiological processes. It is greater challenges to simultaneously identify different biothiols due to their similar molecular structures and chemical characteristics. In this work, we employed a multi-emissive fluorescent probe by sulfonyl benzoxadiazole (SBD) with halogen chloride unit as the interaction site based on aromatic substitution-rearrangement strategy to discriminate Cys and Hcy/GSH.

Molecular engineering of a colorimetric two-photon fluorescent probe for visualizing HS level in lysosome and tumor.

As a multifunctional signaling molecule, hydrogen sulfide (HS) plays an essential role in diverse physiological and pathological processes. The two-photon fluorescence probes detecting HS selectively in vivo could be useful tools to better study the mechanism of diseases. Then, an efficient two-photon lysosome-specific probe 1 has been developed to detect endogenous HS in living cells and mice.

Three-dimensional Cu/C porous composite: Facile fabrication and efficient catalytic reduction of 4-nitrophenol.

Developing a facile method to fabricate new heterogeneous Metal-Organic Framework (MOFs) based catalysts with high catalytic activity and stability has drawn significant attention. Herein, we demonstrate a simple in-situ pyrolysis reduction strategy to fabricate a novel three-dimensional (3D) Cu-based catalyst, which displays an outstanding performance for the decomposition of 4-nitrophenol (4-NP). Detailed characterization including SEM, FTIR, XPS, ICP-OES, HRTEM, SAED, XRD and BET confirmed the formation of the Cu/C porous composites (Cu/C-PC).

A multifunctional two-photon fluorescent probe for detecting HS in wastewater and GSH in vivo.

A novel turn-on fluorescent probe, which coumarin-fused coumarin was used as fluorophore to link with 2, 4- dinitrodiphenyl ether moiety that has high selectivity and sensitivity for HS and thiols, was designed and synthesized. Our probe YB can sensitively react with HS and GSH to release free fluorophore with strong fluorescence signals. The probe YB could use as a significant molecular imaging tool to study the endogenous GSH in living cell and a practical detector for HS in the papermaking wastewater.

A resumable two-photon fluorescent probe for Cu and S based on magnetic silica core-shell FeO@SiO nanoparticles and its application in bioimaging.

A two-photon fluorescent probe for Cu and S has been strategically prepared with naphthalimide derivative platform (NPE) covalently grafted onto the surface of magnetic core-shell FeO@SiO nanoparticles. The probe (NPE-FeO@SiO) exhibits selective response to Cu with enhanced fluorescence and efficient separation of Cu with external magnetic field. The consequent product NPE-FeO@SiO-Cu of NPE-FeO@SiO and Cu can work as an excellent sensor for S by removing Cu from the complex with fluorescence decreased, recovering the fluorescence of the probe.

A two-photon ratiometric ESIPT probe for fast detection and bioimaging of palladium species.

A novel ratiometric ESIPT fluorescent probe, which is specific for palladium species of all the typical oxidation states (0, +2, and +4), has been designed. Notably, based on the excited state intramolecular proton transfer (ESIPT) process, the probe exhibits a ratiometric fluorescent response to palladium species with a low detection limit (9.0 nM, 0.

A reversible ratiometric two-photon lysosome-targeted probe for real-time monitoring of pH changes in living cells.

Lysosome pH is known to be acidic (4.5-5.5) and has emerged as a critical physiological factor for lysosome activities and functions.

A two-photon ratiometric ESIPT probe for the discrimination of different palladium species and its application in bioimaging.

A highly selective ratiometric ESIPT fluorescent probe has been designed for the detection of palladium species of all the typical oxidation states (0, +2, +4). The probe exhibits a ratiometric fluorescence response towards the palladium species in about 20 min at room temperature based on the excited state intramolecular proton transfer (ESIPT) process. Moreover, the probe can discriminate different palladium species (Pd, Pd, Pd) under different detection conditions.

A water-soluble colorimetric two-photon probe for discrimination of different palladium species and its application in bioimaging.

A novel water-soluble colorimetric and fluorescent palladium probe with excellent selectivity and sensitivity has been designed. Notably, based on a palladium triggered terminal allyl ether cleavage reaction, the probe could detect and discriminate Pd(0) and Pd(2+)/Pd(4+) in about 2.5 min at room temperature with a low detection limit (0.

A reusable ratiometric two-photon chemodosimeter for Hg detection based on ESIPT and its application in bioimaging.

A novel ratiometric fluorescent chemodosimeter has been developed for reusable detection of Hg. The chemodosimeter responds to Hg sensitively and selectively with a remarkable fluorescence change from green to blue through hampering the excited state intramolecular proton transfer (ESIPT) process. This recyclable chemodosimeter can remove Hg from water by forming a unique mercury-containing compound, which could be reused in the presence of NaBH.

Thermodynamic and kinetic characterization of hydrogen-deuterium exchange in beta-phase palladium.

A Sieverts' apparatus coupled with a residual gas analyzer (RGA) is an effective method to detect composition variations during isotopic exchange. This experimental setup provides a tool for the thermodynamic and kinetic characterization of H-D isotope exchange on Pd. The H or D concentrations in the gas and solid phases during the exchanges starting from (H(2) + Pd(x)D) and (D(2) + Pd(x)H) in beta-phase Pd were monitored over a temperature range from 173 to 298 K.

Equilibrium isotope effects in the preparation and isothermal decomposition of ternary hydrides Pd(HxD1-x)y (0 < x < 1 and y > 0.6).

A Sieverts' apparatus coupled with a residual gas analysis is used to measure the concentration variations of hydrogen isotopes in the gas and solid phases during exchange and isothermal decomposition of mixed hydrides. beta-phase palladium hydrides with known ratios of H:D, Pd(H x D 1- x ) y (0 < x < 1, y > 0.6), are prepared by H 2 with PdD y or D 2 with PdH y exchange, and their desorption isotherms are reported here at 323 K.

Mechanistic investigations on the heterogeneous solid-state reaction of magnesium amides and lithium hydrides.

Isothermal and non-isothermal kinetic measurements on the chemical reaction between Mg(NH2)(2) and LiH, as well as the thermal decomposition of Mg(NH(2))(2), give apparent activation energies of 88.1 and 130 kJ/mol, respectively, which reveal that the thermal decomposition of Mg(NH2)(2) is unlikely to be an elementary step in the chemical reaction of Mg(NH2)(2) and 2LiH. The H-D exchange between H(delta+) in Mg(NH2)(2) and D(delta-) in LiD gives evidence for the coordinated interaction between amide and hydride.