[Psychological test studies of symptoms in patients with chronic prostatitis and prostadynia].

A total of 123 men with the symptoms of chronic prostatitis, who had been classified as suffering from either prostatitis or prostatodynia on the basis of infection diagnosis, were asked to complete two psychological test forms: the Giessen Symptom Check List (GSCL) and a prostatitis questionnaire. The most striking result was that in the GSCL both groups, in comparison with the test standardization sample, showed a relatively high degree of symptoms (subjective discomfort), particularly in the scales "Tendency to Fatigue" and "Pain in Limbs." The symptoms in the prostatitis questionnaire could be grouped into 4 scales, whereby the main finding was that the patients with prostatitis complained of greater discomfort on the scale "Vegetative Genital Complaints" than those with prostatodynia.

Ultrastructural analysis of sheep lungs after increased intracranial pressure and development of pulmonary edema.

The effect of neurogenic pulmonary edema on the ultrastructure of the gas exchanging region of the mammalian lung is unclear. The present study reports a morphometric and ultrastructural analysis of the alveolar-capillary septa of the lungs of anesthetized sheep subjected to elevated intracranial pressure during hydrostatic recruitment of pulmonary microvascular surface area. In experimental animals septal interstitial thickness was increased and evidence of interstitial edema was presented.

Skin exposure to I blocks thyroid uptake of 131I.

Radioisotopes of I pose an important health risk to man in nuclear accidents associated with electric power generation due to their uptake by the thyroid glands. Topical application of tincture of I or povidone-iodine to the skin of rats has been found to be as effective as oral administration of potassium iodide in blocking thyroid uptake of parenterally administered 131I. If the same effectiveness can be demonstrated in humans, this may be an attractive alternative method of mass protection from radioisotopes of I following nuclear accidents.

Dissecting aneurysms of head and neck.

We analyzed four personal cases and 51 reported cases of dissecting aneurysms of the arteries of the head and neck. Subintimal dissection more commonly affects the intracranial vessels before age 40. In contrast, medial dissection tends to affect extracranial vessels after age 30.

Use of transrectal ultrasonography of the prostate gland and seminal vesicles in andrology--3 years experience.

Benign and malignant prostatic diseases are very common and give rise to significant morbidity and mortality. The Author describe the technical equipment and the procedure of transrectal ultrasonography introduced for investigation of diseases of the prostate gland and seminal vesicles; ultrasonically guided biopsies give important diagnostic indications not only for the oncologist, but also for the specialist in andrology.

Comparison of NMR imaging and aortography for preoperative evaluation of abdominal aortic aneurysm.

Seven patients (five male and two female, age range from 50 to 88) with angiographic proven abdominal aortic aneurysms were evaluated with magnetic resonance (MR) imaging (1.5-kG system) of the abdomen. Images were obtained in transverse, coronal, and saggital planes with three radiofrequency pulse sequences [saturation recovery (SR), inversion recovery (IR), and spin echo (SE)].

Intraarterial ethanol as a long-term occlusive agent in renal, hepatic, and gastrosplenic arteries of pigs.

The renal, hepatic, or gastrosplenic arteries of eleven juvenile pigs were selectively injected intraarterially with 95% ethanol to evaluate its efficacy as an agent for use in permanent occlusion and infarction of the vascular bed supplied by the injected artery. A dose of 2.2 cc/5 kg (1 cc/5 lb) of 95% ethanol was injected over 30-45 sec.

Ureaplasmal infections of the male urogenital tract, in particular prostatitis, and semen quality.

Ureaplasma urealyticum is considered an etiologic agent in urogenital tract infections, especially prostatitis. Using the 'four-specimen technique', diagnosis can be based upon significant numbers of these microorganisms. In ejaculate, the critical number seems to be 10(3) cfu/ml of semen to discriminate between real infection and contamination during urethral passage.

Magnetic resonance imaging in leukodystrophies of childhood.

Magnetic resonance imaging (MRI) is particularly valuable in the diagnosis of childhood brain disorders with abnormal myelination because MRI may identify lesions not always seen with x-ray CT scans. We report the clinical and magnetic resonance findings of six children with leukodystrophy. T2 weighted (spin-echo) images disclosed striking asymmetric involvement of cerebral white matter, particularly in periventricular white matter and visual radiations.

Therapy of priapism in high counting myeloid leukemia--a combined oncological-urological approach. Two case reports.

Two cases of leukemic priapism are described. Both patients underwent a combined oncological (antileukemic chemotherapy, cell depletion by leukapheresis) and urological (transglandular cavernosum-spongiosum shunt, heparin lavage of the corpora cavernosa) therapy. Cytologically necrobiotic tumor cells could be identified in the corpus cavernosum aspirates causing blood stasis in the corpora cavernosa initiating priapism.

[Prostatitis diagnosis. Studies on objectivation and differential diagnosis of various forms of prostatitis].

In 233 patients suffering from chronic prostatitis, increased granulocyte counts in prostatic secretions revealed real inflammation in 111 patients (47,6%): four patients (1,7%) suffered from specific and 22 (9,4%) from chronic bacterial prostatitis. In 85 men (36,5%) "non-bacterial" prostatitis was evident, whereby in 22 (9,4%) ureaplasma-associated prostatitis was obvious. 26 men (11,2%) showed increased granulocyte counts in prostatic secretions, in these cases the mere microbiological finding was C.

Diffusion of ciprofloxacin into prostatic fluid.

To determine whether ciprofloxacin might be efficacious in therapy for chronic bacterial prostatitis, its diffusion into prostatic fluid was studied in ten healthy volunteers. One hour after administering 500 mg ciprofloxacin, the concentration of ciprofloxacin was measured by the agar diffusion method and bioassay. Serum levels were twice as high as in seminal fluid; however, 12 and 24 hours later concentration in seminal fluid was tenfold higher than in serum.

[Epididymitis. Studies on its etiology and pathogenesis with special reference to Chlamydia trachomatis and Ureaplasma urealyticum].

A standardized clinical and microbiological diagnostic examination was conducted on 137 patients with acute or chronic epididymitis (cardinal symptom: painful swelling of the epididymis). Patients with spontaneous secretion from the urethra were examined according to the methods of urethritis diagnosis, patients without it with the four-glass test. Gram-negative bacteria and enterococci were responsible for 27.

Assessment of pulmonary microvascular permeability in acutely prepared sheep.

We hypothesized that the apparent difference in base-line lymph-to-plasma protein concentration ratios (L/P) between acutely and chronically prepared sheep is due to an underlying difference in pulmonary microvascular permeability. Therefore, we sought to determine the pulmonary microvascular osmotic reflection coefficient for acutely prepared sheep, in a manner similar to that used by Parker et al. (Circ.

Computed tomographic findings in akinetic mutism.

Brain-injured children who progress from coma to a sleeplike state of akinetic mutism are often misinterpreted by their parents as having improved. In children with akinetic mutism caused by extensive destruction of the cerebral gray matter, the computed tomographic scan may demonstrate the irreversible nature of the pathologic changes.

Leber's congenital amaurosis. Relationship of structural CNS anomalies to psychomotor retardation.

Three patients (two of them siblings) had Leber's congenital amaurosis and cerebellar disease. Despite blindness and severe motor deficits, all three patients have achieved relatively normal intellectual and psychosocial milestones. Computed tomographic scans, performed in two patients, demonstrated hypoplasia of the cerebellar vermis in both.

Effects of sequential periods of intracranial hypertension on lung fluid balance.

Pulmonary hemodynamics and fluid and protein exchange were examined in dogs subjected to three successive periods of intracranial hypertension. Results indicate that the alteration in lung fluid balance is due to increased microvascular surface area following capillary recruitment. The relationship to the mechanism of neurogenic pulmonary edema is discussed.

Rheumatoid factor-negative arthritis, especially ankylosing spondylitis, and infections of the male urogenital tract.

146 men with rheumatoid factor-negative (sero-negative) arthritis, i.e., 97 patients with ankylosing spondylitis, 36 patients with Reiter's syndrome, and 13 patients with reactive arthritis, were examined for infections of the urogenital tract by following recently established criteria.

[Enzyme-linked immunosorbent assay (ELISA) for IgG- and IgM antibodies in chlamydial infections of humans].

The development and evaluation of an indirect ELISA for IgG and IgM antibodies in human sera against the genus-specific chlamydial antigen is described. Application of commercial anti-immunoglobulins for production of conjugates usually resulted in direct conjugate/antigen reactions. Therefore, all immunoreagents had to be prepared by the authors.

Quantitative studies on the role of Ureaplasma urealyticum in non-gonococcal urethritis and chronic prostatitis.

Quantitative determinations of U. urealyticum and M. hominis have been performed in 164 men with non-gonococcal urethritis (NGU) and 597 patients with chronic prostatitis.

[The diagnosis of sexual function disorders. Screening studies of angiological factors in disorders of sexual function].

106 outpatients, visiting our department because of sexual disturbances, underwent a standardized examination program. The following anamnestic data and clinical and laboratory findings were recorded: Details of the vita sexualis, evidences for genital and vascular diseases, endocrine abnormalities including diabetes mellitus, drug consumption. Genital organs were judged by clinical examination, blood-pressure, oscillography and penis-flow-index were measured, hormones, sugar and lipids in blood serum were determined, with respect to a special indication, cavernosography and pelvic angiography were performed, and prostatic inflammation was excluded.

Significance of Chlamydia trachomatis in "abacterial" prostatitis.

Chlamydia (C.) trachomatis was isolated in McCoy cell cultures from urethral swabs after prostatic massage, of 43 out of 233 patients (18.5%) with symptoms of "abacterial" prostatitis, but also from 5 out of 65 control persons (7.

Studies on the role of Ureaplasma urealyticum and Mycoplasma hominis in prostatitis.

It has definitely been demonstrated that Ureaplasma urealyticum is one etiologic agent of nongonococcal urethritis, a sexually transmitted disease. For this reason it seemed possible that the organisms might cause ascending inflammatory reactions of the prostate. Quantitative determinations of ureaplasmas and Mycoplasma hominis, together with localization studies, were therefore performed to elucidate the importance of these microorganisms in patients with chronic prostatitis.